The Cytogenetic Effects of Crude Ethanol Extracts of Petroselium Crspum Leaves on Bone Marrow In Mice (Mus Musculus)

Abstract

This study aimed to investigate the cytogenetic effects of ethanol extractof Petroselium crispum leaves on somatic cells of albino mice Mus musculus.Fourdoses (250,500,1000,2000)mgkg were used.Three tests,mitoticindex,micronucleus formation and chromosomal aberration.Results indicated that the extracts have significant effects p<0.05 wereused. which inhibit somatic division in 250 and 500mgkg doses after 21 and 28days (P<0.05) of treatment by comparison with the control. Ethanolic leavesextract showed little effect on micronucleus formation and chromosomalaberration.It can be concluded that the crude extract of leaves for the above plant canbe used in cancer treatment of cancer since it has the ability in inhibition ofsomatic division which has.