Effect of different doses of mercury chloride on the device Almithlee proliferative eggs in Male Mice

Abstract

This study was achieved in order to study the effects of methyl mercury chloride, injected subcutaneously on the some of the reproductive parameters of the strain: Balb C. The following biological parameters were studied in the animals that received either one are several injection of zero (contral), 1. 2, 2 and 2.8mg of methyl mercury chloride/ Kg body weight: 1-Morphology and body weight of the testes.2-Diameter of seniniferous tubules and percentage of affected tubules.3-Numbers of different spermatogenic cells in each tubule such as spermatogonia, primary and secondary spermatocytes, spermatids and sertali- cells.Treatment with methyl mercury chloride have produced significant degress of damage in the testes & that these effects were proprtionated with the concentration.Histological studies of these testes showed that methyl mercury chloride induced significant reductions in the diameters of the seminiferous tubules particulary in the testes of animals that received the highest concentration. Methyl mercury chloride was also found to induce a conspicuous damage in these tubules.The study showed that treatment with methyl mercury chloride coused significant reductions in the mean number of the different spermatogenic cells (spermaogonia, primary and secondary spermatacyts, speratides and sertoli- cells). These reductions were proportionated with the concentration of the injected substance.