بعض التاثيرات الماعية لمستخلص زهرة الدفلة الحمراء Nerium oleander في ذكور الفئران البيض Mus musculus .

Abstract

The present study was designd to shed some light on the immunological effects of the flower extract of Nerium oleander.The effects of the extract on the immuno- suppressive action of the drug Mytomicine-C were also investigated in vivo using albino muose (Mus musculus) . The immunological tests included total and differential counts of leucocytes, phagocytic index of peritoneal cells and specific activity of adenosine deaminase in thymic cell homogenate.Three doses of flower extract were tested , they were (11,22,33mg/kg) did not show negative effects on the activity of immune system of laboratory animals. In contrast, an obvious ectivating effects of this extract were observed regarding the activation of the immune system. This effect was dose – dependent as shown above.