Effect of prostaglandin and PMSG on prolificacy and some serum biochemical changes of Hamdani ewes synchronized with intravaginal progestagen

Abstract

The study was designed to evaluate the efficiency of three different hormonal treatment of estrous synchronization in Hamdani ewes reared in northern Iraq (Kardstan). During the breeding season July 2006, 40 adult Hamdani ewes were randomly allocated to four equal groups. The first group T1was treated with inravaginal progestagen sponges containing 40 mg (FGA) for 14 days. whereas second group T2 was treated as T1 group but injected with 500IU PMSG at the sponges removal, while the third group T3 was treated with progestagen intravaginal sponges for 10 days, at time of sponges withdrawal prostaglandin F2ά 5mg (Dinoprost) was injected, the last group left as control group C. The estrous response was comparable in treatment, T1 (90%) T2 (100%), T3 (100%) as compared with group C (80%) The T2 and T3 were the higher estrous response than the other groups. The highest and lowest number that lamed was 100% in groupT2 and 70% in group C. Lambing rate and twin born lamb was higher in group T2. The biochemical examined were included Aspartate transaminase (AST), Alanine transaminase (ALT), and Alkaline phosphatase (ALP), also concentrations of total protein, albumin, total cholesterol, ionized calcium, inorganic phosphor and serum glucose. Data show that there was no significant effect of hormonal treatment .There were significant (P≤0.05) increased in activities of AST, ALT and ALP enzymes also concentration of total protein and concentration of total cholesterol, during late pregnancy and at parturition. The concentrations of serum glucose and inorganic phosphor were significant decreased during late stage of pregnancy and at parturition there were no significantly effects of pregnancy and parturition on the concentrations of serum glucose and ionized calcium. Its concluded from these results that the administration of an impregnate intravaginal sponges for 14 days plus a dose of 500IU PMSG was increased, lambing rate and litter size as compared to the other hormonal treatment Considered.