Physiological and epidemiological studies on Kala- azar disease in Missan

Abstract

Summary:The present study was made to known the effect of Kala-azar disease on some biochemical parametersin children. The GOT, GPT ALP, total protein and total bilirubin were measured in 50 infected children forboth sex (21 male and 29 female). The research also included the study of (number of infected children andtheir ages during the 16 last year and months of year).The results showed significant increase (P<0.005)in male and high significant (P<0.005)in female in GOTin the infected children compared with health children .The value of GPT didn’t show significant differ inmale ,but its show high significant increase (P<0.001) in the infected female.The value of ALP show significant increase (P<0.005) in infected male, while its value didn’t showsignificant different in female. The values of total protein and bilirubin don’t reach to significant level ininfected children compared with control. The percent of infection differ during the last 16 years ago. Highpercent in the infected male were record in 2007 (64%) and low percent in 1995 (41%), high percent of theinfected female were record in 1995 (59%) and low percent in 2007 (36 %.)The age of children between 1-2 year recorded high number of infection about (961) case , while the agegreater than 5 year recorded low number of infection ( 31) case. The month of year also effect on thenumber of infection, high percent of the infection were recorded during Jenuary (17.7%) and low percent inAugest (2.4%).