Effect Of Selenium Supplementation On Humeral Immune Response Against Infectious Bursal Disease Vaccine In Broiler Chicks.

Abstract

Supplementation of Selenium in diets of field animals enhances the immune status and ability of the immune system to respond to disease challenges. The objective of the present study was to know the impact of selenium supplementation on humoral immune response against IBD vaccine in broiler chicks. A total of (160) commercial broiler male chicks were raised up to 50 days of age under controlled experimental conditions. The chicks were randomly divided into four equal groups (A, B, C and D) at age of day one. Fourty chicks for each. Chicks of groups (A and B) were not supplemented with selenium, while those of groups (C and D) were given selenium 0.05 mg/Kg of feed from day one to day (50). Chickens of groups (B and D) were vaccinated against (IBD) using live attenuated (IBD) vaccine at the age of day (10) then, boosted at (25, 35,45) days of ages. The effect of selenium on humoral immune response was evaluated by recording antibody titres against IBD through indirect (ELISA) test in the sera of chicks of treated groups. These results indicate that there were significant differences (P<0.05) in the mean values of titer of antibodies against (IBDV) among all the treated groups at (15, 30, 40, 50) days of age. So that; the results showed a significant increasing (P<0.05) in the mean values of titer of antibodies against (IBDV) of chickens of group (D) in comparsion with other treated group at (30, 40, 50) day of age. It is concluded that selenium supplementation in diets of poultry help to increase humoral immune response post vaccination against live attenuated infectious bursal disease (IBD) in broiler chicks.