The Study of Hormons and Biochemical in the Women with Polycystic Ovary Syndrome in Tikrit city and its Suburbs

Abstract

This study has taken change occurred in some biochemical characteristics and their relation with the blood components which take place to women infected with polycystic ovary syndrome which was considered as gynecology that effect apparently the infected ones and same side effects could accompany this kind of chronic disease like Hypertention, Dialbetes, Dislipdimia in the body and sometime Cardias –arteries.This study has been carrird out (189)blood sample of these infected women who has polycystic ovary syndrome .After diagnosis of their cases has been known from the clinical and laboratorial test ,they also undergo the Uiter Sound pictures. These women aged (17-45)years. They sexual hormones concentrations have been measured (LH, FSH, PROL, Testos) .They level of the lipid component concentrations in the blood plasma of these infected women was also measured .As well as the measurment of the blood sugar ,performed there is also field study to each patient by asking her some questions including :Age,arriage, Discipline of menstrual cycle ,the relationship between the menstrual cycle and nursery , weight ,height ,and chronic disease ,the druge used and operations in the ovary .The results of the research have shown significant rise of the (LH, FSH, PROL, Teston )compared with controlling group with significant levels of 0.001)which shown that the highest concentrations of prolactin (20.61+9.73) < p )ng/ml within these suffering patients of the Hypertention and Diabentes ,and the lowest concentrations was (9.55+0.51) ng/ml. This shows that the highest lowe of the LH(19.96+3.30)MLU/ml .within the patients who suffer from Hypertention and Diabetes. and the lowest one of (6.61+1.12)MIU/ml ,Asfor the FSH the highest level was (2.83+1.2)MIU/ml .Whilst the highest concentrations of Testos. (1.33+0.13) ng/ml within these suffering patients who suffered from Hypertention and the lowest one was (0.33+0.02)ng/ml. The results in lipid level in (p 0.001) where the highest concentrations of Cholesterol (7.19+4.1) mmol /L of the Hypertention and Diabetes .Patients while the lowest one was (4.01+1.99)mmol/L of the some Patients ,while the highest concentrations of Tighlyceride (mmol/L ,and the lowest one was (1.1+0.01) mmol/ L. As for the concentrations of HDL, the highest one was (0.71+0.27) mmol/ L, and the lowest one was (0.32+0.022) mmol/L of the Hypertentionand patients. For the one VLDL, LDL, the highest conentrations was successigely (0.44+0.18), (5.67+2.69) mmol /L and the lowest one was (0.24+0.14), (2.11+1.87) mmol / L. The results of the late study have referred to f pregnancies occurrence in patient when they have taken the Metformin druge in an arranged way ,the concentrations of prolactin has been lowered when they take Parlodel druge .The average obesity has been lowered too as well as Hirsutismin the chin and most achareras .It was also found that the P.C.O. cases have been risen within the married women rather than the un married .This study also showes the increase of the amenorrhea for several months of the patients of this disease ,through the field study ,it was shown that more than one patients of P.C.O.S were found in the same family .