Effect of Leaves and Fruits Extracts of Melia azedarach Against Some Pathogenic Fungi Isolated from Human

Abstract

Study of the effect of aqueous extract of leaves and fruits of Melia azedarach against growth of Aspergillus niger and A. fumigatus isolated from external ear swabs had been infected with Aspergillosis, Showed that aqueous extract of fruits was more effective than its leaves extracts, Which its inhibition percent was 100% with concentrations 30 and 25 mg/cm3 on growth of A. fumigatus and on concentration 30 mg/cm3 on A. niger, It was also showed that minimum inhibition concentration (MIC) was 11.1% and 11.7% on A. niger and A. fumigatus respectively in concentration 5 mg/cm3, The study also showed significant differences between all treatments and control, The inhibition percent in leaves extract was 100% on A. fumigatus with concentration 30 mg/cm3 while the effect were less on fungal growth against A. niger which the inhibition percent was 64.2% with the same concentration above