Histological changes of the submandibular Salirary gland of mice maintained on a liquid diet

Abstract

The purpose of this study was to examine the histological alterations that occurred in the submandibular glands of mice fed a liquid diet compared to a solid diet. Thirty-six mice were randomly divided into two groups. The control group received a solid diet, and the experimental group received a liquid diet. The mice were killed after 21 days. The glands were prepared in paraffin and analyzed with a light microscope. The results showed a statistically significant reduction of the submandibular gland acini of the mice from the experimental group compared to the control group, in which the diameter of serous acini in experimental group was (25.2), mucous acini (30.6 ), while for the control group the diameter of serous acini was (35.24), mucous acini (39.55). There was no significant reduction in the diameter and volume of both the straited ducts and the interstitial connective tissue