Effect of Obesity on Some Liver Functions , Biochemical and Blood Parameters in Adult

Abstract

This research has been designed to study the effect of obesity on some liver functions , biochemical and blood variables for adult ( males and females ) . The sample was 300 persons ranging in age from ( 20- 60 + 2) years , they have been classified into three weight groups depending on the BMI . The normal weight group 92 persons are regarded as a control group for the two other groups , the over weight group 100 persons and the obese group 72 persons . 36 persons having chronic diseases were excluded , so the sample under study has become 264 persons divided into 165 males and 99 females forming three age groups the first group 20-29 years , the second group 30 -39 years and the third group is 40 years and above . The results of the study showed high level of alanin aminotransferase (ALT) and alkaline phosphatase (ALP) enzymes in the obese persons group compared with the control group for males and females . As for the aspartate aminotransferase (AST) enzyme , no significant change has been shown compared with the control group . The level of the three enzymes in the over weight and obese groups showed significant increase compared with the control group as the persons get older . As for as the biochemical variables are concerned , the results showed a significant blood glucose increase in the obese group compared with the control group for males and females . As for the lipids , the results showed significant changes in all levels of variable for the obese group , males and females compared with the control group except for the cholesterol and HDL which did not show a significant change for females. The blood tests , in this study showed that the total number of WBC had a significant change in the over weight and obese groups compared with the control group . As for the hemoglobin , the results showed no significant quantity change in females , and for both groups compared with the control group . It was suggested , through this study , that the ALT enzyme is the most significant indicator in demonstrating liver diseases .