Certain hematological values of the ß-thalassaemia major among Mosul population

Abstract

Ninety seven blood samples of the Beta-thalassemic patients were collected from patients registered in Mosul thalassemic center for the period 2001-2002 distributed in (52 males with 64% and 45females with 46% ratio) aged 3.5-24 years old, and 87 blood samples of apparently healthy volunteers aged 3.5-24 years old too distributed in (56males with 65% and 31females with 35% ratio) for the same age and period time collected from Ibn Al-Ather Teaching Pediatric Hospital in Mosul City. From Hemoglobin (Hb), Packed Cell Volume (PCV %) and blood groups determined two trails, analysis showed, there were no significant differences (p<0.05) between and within groups of age, sex and Hb values for normal and B-thalassemic major patients, while there was a significant differences (p<0.05) between and within groups of, PCV and Hb values. The B-thalassemic index was less than 0.75, this equal to about 8.50g/dl Hb value. Beta-thalassaemia major can classify in the first time to four levels as: very sever, sever, mild and moderate status, those have hemoglobin values as: less than 7.50, 7.50-8.00, 8.00-8.50 and 8.50-9.30g/dl. The blood group of Beta-thalassemic can be arranged in decreasing order O+, A+, B+, AB+, O- and A- with samples distribution 48.61, 23.61, 22.22, 2.28, 1.39 and 1.39% respectively. The good and preferred Beta-thalassaemic life time of patient was in the age group 6-12 yrs old (higher Hb value, hemoglobin ratio and PCV).