Hormonal Contents of Two Types of Black Seed (Nigella sativa) Oil: Comparative Study

Abstract

The use of black seed (Nigella sativa) capsules as a herbal therapy to lower blood glucose in diabetic patients are associated with menstrual cycle irregularities. The present study was designed to analyses and to compare between two types of Nigella sativa (N.sativa) agricultures in Mosul region and those imports from Saudi Arabia Kingdom, and to investigate the levels of hormones in volatile oil of black seed that regulate menstrual cycle that might be present in Nigella sativa. Volatile oil of N.sativa was extracted by steam distillation using diethyl ether as an organic solvent.Then, hormones analysis were done using (miniVIDAS software version) instrument. Results of present study showed a presence of considerable amount of sex hormones estradiol, progesterone, prolactin, testosterone, FSH and LH .This might interpret the cause of menstrual cycle irregularities occur when black seed capsule was taken as a herbal therapy to lower blood glucose in diabetic patients.