The in vitro Antibacterial actiyity o f Citrus aurantifolia var acidica fruits

Abstract

The r, rrto anribacreriat acrivity of Crrrr auruntilotia fruirs (CA) is being reDorred..lheeextraction methods were tried as : Hot water (HWCA I cotd warer (CWCA) , and aico-noljc 1aCAl .The $reening ofantibdcreriat ,rclivi[ {AA) was done b) agar diffu.ion lechnique (ADTj . MrnrmLmrnnrb,lory ( oncentrnlion fMtC).tudiec $ere made by dgar drluLion lechniqu; (ADT). Ll. ne uoaMIC studies were conducted on Muller - Hinton agar (NaHA) . fhe i, vr'lro Ae frora hishest to thelowest_effective were as fo olvs, ACA, CWCA,;d HWC,{ respectivety. lr" uri, "7*":.rzs ,6.25 ,6-25 and 12.5 mg/nt for ,S. aureus , prcteus wtsaris , rseiaonoits aeruginosa artd E. c,Jtirespecrlv.ely . K. peneumarlae was unaffecied by ACA, CWCA and HWCA . Such'finding may be dueto capsul€ permeability masking effecLACA can be re€ommended or a in ,itro basis as antibacterial agent in topical pharmac€uticalpreparations and as canned food preseNative