INFLUENCE OF SOME WEAK ACIDS, WEAK BASES AND SALTS AGAINST SOME PATHOGENIC MICROORGANISMS

Abstract

ABSTRACT: This study was designed to investigate of antibacterial activity of many chemical compounds includes : 4 % imidazole, 2 % imidazole, 1% imidazole , 2.5% sodium citrate, 5% sodium citrate, 5% sodium acetate,2.5% acetic acid, 5% acetic acid, 5% citric acid, 5% magnesium chloride (MgCl2.6H2O2), 5% magnesium sulphate (MgSo4), 5% sodium carbonate (Na2Co3), 5% potassium dichromate (K2Cr2O7), 5% potassium permanganate (KMnO4) and 5% sodium hydrogen carbonate (NaHCO3 ) have been carried out against (Escherichia coli, Pseudomonas aeruginosa , Klebsiella oxytoca , Proteus mirablis and Serratia liquefaciens ) that diagnosed by API 20 E technique and Staphylococcus aureus , Pathogenic fungal strains (Aspergillus niger, A. flavus, A. fumagatus, Fusarium sp. and Candida albicans ). The results showed 4 % imidazole, 2 % imidazole, 1% imidazole, sodium acetate , 2.5% acetic acid, 5% acetic acid, 5% citric acid , 5% Na2CO3, K2Cr2O7 have different antibacterial activity according to types of bacteria, whereas 4 % imidazole, 2 % imidazole , 2.5% acetic acid, 5% acetic acid and 5% Na2Co3 only have antifungal activity, and showed compounds: 4 % imidazole & K2Cr2O7 have antimicrobial activity more than standard positive control antibiotic.