THE ONE MONTH OUTCOME OF PATIENTS WITH ACUTE CORONARY SYNDROME IN RELATION TO WBC COUNT

Abstract

ABSTRACTBACKGROUND:Inflammation has been shown to play a role in atherosclerosis and CHD .an elevated leukocyte count is associated with adverse hospital outcome in patients presented with acute coronary syndrome.OBJECTIVE:This study was designed to determine the association between baseline total WBC count and the hospital mortality and complication (heart failure) in patients with ACS including STEMI, NSTEMI, and UAnd to verify if this parameter has significant predicative power pf cFinica{ severity and out come.PATIENTS AND METHODS:The relationship between baseline total WBC count. with hospital mortality and complication (heart failure) and clinical outcome in 57 patients with ACS admitted to the CCU in AL-SADAR teaching hospital from the first of April to the 30th of august 2007has been tested ,diseases were evaluated for seventeen (17) patients with STEMI ,twenty(20) patients with NSTEMI , twenty (20) patients with UA , venous blood samples were taking from each patient for baseline total WBC count ,fasting lipid profile ,random blood sugar .comparison between those patients with STEMI, NSTEMI,UA were conducted includes one inflammatory marker (WBC).RESULTS: High total baseline WBC count was associated with high cardiovascular risk, heart failure and mortality (19.2%, 12.2 %, and 8.77 %) among patients with STEM I, NSTEMI, and UA respectively.CONCLUSON:In patients with ACS, initial leukocyte count is predictive of outcome and as the level increased the complications increase and the clinical out come adversely affected.