Effect of watery extract for the roots of Salvadora persica on the concentration of the sexual hormones and number of fertility parameters of white mice females

Abstract

AbstractThe research has been applied on (70)Mouse females related to (Balb/C) age from(10-12) weeks , and their weight (19-25)g. As well as (7) of white mice males had used after being tested as fertile to do the mating : The mice had been divided in to three groups depending on the number of estrus cycle . Where as , the group (A) included female in the first estrus cycle . While the group (B) included females in the second estrus cycle.The group(C) included females in the third estrus cycle with (20) mice females for each group ,and these groups had been re-divided in to two sub-group for each one depending on the given dose to (10) mice females for each sub-group, where the first group has been given the dose (50)mg/kg from the body weight of watery extract for roots of Salvadora persica,While the second sub0group has been given (100)mg/kg of watery extract for roots of Salvadora persica for all groups above all the period of experience.The Concentration of sexual hormones have been estimated and count of numbers of breedings and the weights of breedings , and the numbers of corporus lutei and the percentage of fertility to know the effect of the watery extract for roots of Salvadora persica on the function and efficiency of reproductive system of mice females . The results of the research showed significant decrease of number of breedings, corporus lutei and fertility percentage of the examined groups as compared with control group , while , has not found any slight differences in the weights of the breedings for all groups as compared with control group ,The concentrations of hormones (FSH, LH ,Estrogen ) has decreased of all groups compared with control group , while the concentration of progesterone has increased in all groups compared with control group , and also the concentration of prolactin has increased in the groups (B,C) compared with control group.

Keywords

Extract, roots, mice