IMMUNIZATION TRIAL OF SHEEP AGAINST HYDATID CYST INFECTION

Abstract

This study was conducted to evaluate the role of vaccination trial of sheep with different types of hydatid cyst antigens (hydatid cyst fluid, protoscolecses and laminated layer ).in the prevention and control of hydatid cyst infection .The animals in all groups received Echinococcus granulosus egg as challenge after the third injection of antigens . Serum antibody responded of vaccinated animals with different antigens studied during the period of study , the results revealed that ,the titer of antibodydepend on indirect heamagglutination test after 21 days and 6 months were 640 and 320 respectively when hydatid cyst fluid antigen was used Also it was 320 and 160 respectively when protoscolisces and laminated layer antigen was used .The animals observed over a year after vaccination and the observation show reduction in the hydatid cyst growth in the vaccinated groups, whears the control group show growth of small cyst in the liver and lung.