Effect of oil Newcastle disease vaccine on thyroid gland hormones T3,T4

Abstract

This research was conducted to investigate the effect of vaccination by oil Newcastle disease vaccine on T3 and T4 level of thyroid gland in broiler chicken. For this purpose 100, one day old chicks, Hubbard were used in the experiment, chicks were allocated randomly in to two groups, and each group was containing 50 chicks. Chicks in the first group were vaccinated by oil Newcastle disease vaccine during 10th day old, were as, chicks in the second group was left with out vaccination, regarded as control group. Body weight and weight gain were recorded every two weeks of the experiment. Antibody titer level was evaluated by HI test. Mean while, T3 and T4 level were evaluated by ELISA. Result were indicated an increase of antibody titer ( p<0.01) and T4 level (p<0.05) in chicks which were vaccinated oily ND vaccine. Where as, T3 level was non significant difference in to two groups, in addition, there no significant difference in mean Body weight and weight gain in the two groups. It was concluded that oily Newcastle disease vaccine resulted in elevation of Antibody titer and T4 in broiler chicken.