Study the Correlation of Anti-gliadin IgA & IgG with Iron & Total Iron Binding Capacity & Albumin in sera of Patients with Celiac Disease

Abstract

Celiac disease (CD) is characterized by malabsorption of nutrients , chronic inflammation and damage of small intestinal mucosa caused by the ingestion of gliadin fraction of wheat gluten and barley . Since the anemia its diagnosis the CD, therefore were measured iron, total iron binding capacity(T.I.B.C.) , and its relationship with antigliadin IgG,IgA and serum albumin. Thirty patients with CD were studied and compared with twenty healthy individuals. Significant elevation of iron and albumin and anti-gliadin IgG,IgA were observed in the sera of patients with CD compared with the control group. Also a significant negative correlation between anti-gliadin IgG,IgA and iron were found in the sera of patients with CD while a non significant correlation were found between albumin and anti-gliadin IgG,IgA in the sera of patients with CD.