Study the effects of toxic mushrooms also Bipolaris holmii in some systems vital to the male rat White

Abstract

The included this studying of known on ability B.holmii to production mycotoxins were effect thought studying in liver system in white rat males .The results indicated that fungus produced one to phenolic toxic compound that was contained on phenolic cycle with aldehyid methyl group .The toxic compound that caused influence of physiological parameters of white blood cells ( W.B.Cs) were increased intreated blood animal of dose (1) mg/Kg to (4900) cell/mm3 .In the same time of the level of Hb also decreased to 100gm/mL , that dose caused increased for enzymes normal level which reach GPT , GOT to (33 , 31.2 ) IU/L in respectively .That comparated with control treatment that reached white Blood cell and Hb with enzymes level that (3100) cell/mm3 , (13) gm/mL, and (6.4 , 7.7 ) IU/L in respectively .The animal were treated by with increased doses a compounding the count of white blood cells were decreased in P.C.V that reach (46 ) % in (1) mg/ Kg .In addition for sever toxic influence in some organic animal tissue and represented of caused between vascular congestion and central vascular adhesive in liver and accumulation of inflammatory cells due to liver damage .The Section was gaved showed from white rat males treatment by phenolic extract compound from B.holmii that presented pathology changing that represented of analysis villi in small intestines and atrophy acompared with vill dise function .