Inhibitory Effect Of Oxadiazooles And Thiadiazoles In Vitro On Serum Alkaline Phosphatase Enzyme Of Pregnant Woman

Abstract

Abstract:To assess the inhibitory effect of oxadiazole and thiadiazole derivativeson serum alkaline phosphatase level of pregnant in vitro. A cross-sectional studyon 34 pregnant women was carried out at Al-Kadhumia Teaching Hospital. The mechanism of Inhibitory effect of Oxadiazoles and Thiadiazoles derivatives in vitro on alkaline phosphatase enzyme of pregnant women due to thedephosphorylation reaction which block the ALP activity.Key Words: Oxadiazoles, Thiadiazoles, serum alkaline phosphatase