In Vitro Inhibitory Effect of Cyperus rotundus L Crude Extracts on Mouth Isolates of Streptococcus mutans and Candida albicans

Abstract

Abstract:Streptococcus mutans is a normal flora bacteria found in human oral cavity,which cause dental caries and bad breathe oder. This project considered as an explorerstudy for the inhibitory effect of Cyperus rotundus L. crude extract on S. mutans andCandida albicans by agar well diffusion method.Extract of plant with three concentrations (8,16and 32 fold dilution of the MIC)were prepared and investigated for antibacterial activity. The minimal inhibitoryconcentration (MIC) against S. mutans of crude extract was 5 mg/ml. Crude extractalso tested for antimicrobial susceptibility compared with standard antibiotickanamycin. The three concentrations of the extract showed high effect on the growthof Streptococcus mutans. The means of inhibition zone diameters were 20.1, 23.4, and25.2 mm for Streptococcus mutans. The largest inhibition zone 25.2 mm in diameter