Synthesis and Studies The Biological Activity of New Azo Compounds
Abstract
The cyclohexanone was subjected to Hantzsch synthesis by treating with iodine and thiourea to give an intermediate 2-amino-4,5,6,7- tetrahydrobenzothiazole. This was then diazotized and coupled with various phenols and naphtholes derivatives to give a series of new disperse dyes. These azo derivatives were characterized by spectral methods 1HNMR , FT-IR, UV-VIS.. These derivatives were tested against three microorganisms Klebsiella, Pseudomonas aeuroginosa and Escherichia Coli. Some of azo compounds was slightly and non active while azo-2-naphthol was highly acive against all the bacteria species tested.
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