Serum total sialic acids concentrations in hyperprolactinimic infertile women and their relations to some reproductive hormones

Abstract

The study consist of 24 hyperprolactinimic women (patients), age range 17-38 (mean 25.4±1.1) and fifteen healthy women (control), age range 18-36 (mean 28.8±1.1) were included in this study. Prolactin (PRL) and reproductive hormones (FSH and LH) were measured by enzymatic immunoassay (EIA) method, and resorcinol method for serum TSA. Serum PRL, LH and TSA levels in hyperprolactinimic women were significantly elevated in compare to normal women, while FSH was showed no significant different. There is no relationship between TSA and hormones levels, but there is positive relation between PRL and FSH (r= 0.578) in control group, FSH and LH (r=0.419) in patients. It can be concluded that there is an elevation in TSA levels, but not affected by hormonal levels, and the causes of this elevation may be caused by other reasons.