Study of Some Trace Elements and Antioxidant Vitamins in Sera of Iraqi Women with Toxoplasmosis


Toxoplasmosis is a common infection that occurs in humans and other warm-blooded animals usually caused by the parasite Toxoplasma gondii (T. gondii). It causes serious problems to the pregnant women that lead to incidence an abortion. This study was aimed to investigate the alterations in the levels of vitamins (A, B6, C, D and E) and some trace elements Zn, Cu, Fe, and Mg in the sera of women with toxoplasmosis with a history of congenitally infected new born, and compare them with the results of age matched healthy volunteers as control group. Thirty five patients with positive anti-T gondii (IgG) antibodies and 15 healthy individuals were included in this study. The levels of serum vitamins were measured using high performance liquid chromatography technique, while serum Zn, Cu, Fe and Mg concentrations were measured using atomic absorption spectrophotometry. Although, there was no significant variations in serum Zn, Cu and Mg levels, serum Fe exhibited significant depression in its concentration in the patients group compared to the control. However, serum vitamins (A, B6, C, D and E) were observed to be decreased significantly in patients when compared with those of control group. In conclusion, the results indicated that the levels of antioxidant vitamins and Fe may have an important role to increase possibility of exposure to toxoplasmosis in women.