Evaluation of plateletpheresis procedure in blood component separation unit of Bone Marrow Transplant Center

Abstract

AbstractBackground: Platelet concentrate can be harvested by apheresis using blood cell separator. In this study; plateletpheresis was evaluated , regarding the safety and clinical effect of the procedure , and quality of the product Methods: The study carried out in blood separation unit of Bone Marrow Transplant Center (BMTC) in Children Welfare Teaching Hospital using blood cell separator. The donors selected according to the criteria for whole blood donor selection with limited clinical examination. Hb estimation, WBC counting and platelets counting were carried out on the donors , pre and post donation , and platelets counted in the product. Results: The results reflect the safety of the procedure; there were no significant clinical changes between pre and post donation regarding pulse rate, blood pressure and temperature, beside that there were no significant changes in Hb concentration and WBC count between pre and post donation , while the drop in platelet count of the donors after donation was of no clinical effect. Only 30% of donors show numbness around mouth . Regarding the quality of the product, 20% of platelet units contain more than 3x1011 platelets, while the other units contain less than that slightly. Conclusion: The procedure of platelet pheresis in blood separation unit of BMTC was safe and effective in harvesting platelet from platelet donors in short time.Key Words: Plateletpheresis , platelet concentrate , blood components separation unit