THE EFFECT OF TAURINE ON REPRODUCTIVE EFFICIENCY IN MALE RATS FED HIGH CHOLESTEROL DIET
Abstract
The study designed to use high cholesterol diet to male rats(Rattusnorvegicus) and asses the ability of the different concentrations of taurine to protectthe reproduction from the harmful effect of hypercholesterolemia during 4 weeks oftreatment .Thirty six adult male rats were used, randomly divided into six equalgroups (six for each)as control and five treatment groups. Control of animals were fedon the standard ration. First treated group was supplied with the standard ration inaddition to 1.5% taurine . Second treated group was supplied with standard ration inaddition to 1.5% cholesterol .Third, Fourth and Fifth treated groups were suppliedwith standard ration in addition to 1.5% cholesterol and 2,3and 4% taurine /kg rationrespectively and were handled for four weeks. At the end of the experiment the bloodserum samples were collect and FSH, LH, testosterone and estrogen levels were takenand sperm vitality was recorded in addition to the weight of testis and epididymiswere recorded. The results revealed to the positive role of taurine in protection ofreproductive from the pad effect of hypercholesterolemia in male rats .The taurine ledto increase in Gonadotropin hormones FSH and LH in addition to the testosteroneafter it has been reduced due to cholesterol in the ration and as a results togonadotropin and testosterone hormone improvement ,the sperm viability wasimproved as well after it was decline due to high cholesterol addition in experimental
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