Synthesis and Identification some of heterocyclic compounds from imidazole derivatives

Abstract

Abstract This reserch involved hetrocyclic compounds such as ( β-Lactam derivatives , Thiazolidine-4- one derivatives , midazolidin-4-one derivatives) were prepared by reaction between 4 -( 1H–benzo [d]imidazol -2-yl aniline (1) with p-amino acetophenone to get N-( 1- ( 4-aminophenyl ) ethylidene ) -4-(1H - benzo[d] imidazol -2-yl)aniline(2) which reacts with substutid aromatic aldehyde to get 4-(1-(( 4-( 1H-benzo [d] imidazol -2- yl ) phenyl ) imino )ethy l) -N-( derivative benzylidene) aniline . The cyclization of (3-6) with chloroacetylchloride , thioglycollicacid and α-aminoacid such as glycine and aniline give the corresponding β-lactam (7-10) , thiazolidine-4-one (11-14) and imidazolidine-4-one (15-22) derivatives..All this compounds characterized by means of FT- IR , 1H-NMR, and follow reaction by Rf - TLC and Measure melting point .