Hematological and Biochemical Changes in Albino Rats Receiving Aqueous Extract of O. basilicum Leaves

Abstract

The present study had been designed to determine The effect of oral administration of aqueous extract of 0ccimum basilicum leaves on some Hematological and biochemical parameters and on the level of blood proteins(total protein , albumin and immunoglobulin) of adult rats . 20 adult albino rats (10 males and 10 females) weighting between 100-150 g obtained from the disease free stock of the animal house ,biology Department, University of Babylon were used for the study The rats were divided according to sex into four groups with five rats each, as follows: Group Mc (Male control group receiving distilled water); Group Fc (Female control group receiving distilled water); Group Mt (Male test group receiving aqueous extract of O. basilicum leaves); Group Ft (Female test group receiving aqueous extract of O. basilicum leaves). There was increase in the amount of hemoglobin, PCV and neutrophils levels (P > 0.05). lymphocytes level was decreased on administration of the extract in both male ( 58.17 ± o.81 ) and female ( 60.76 ± 0.36 ) Serum biochemical results showed significant increase of serum total protein , albumin and immunoglobulin .