Table of content

Medical Journal of Babylon

مجلة بابل الطبية

ISSN: 1812156X 23126760
Publisher: Babylon University
Faculty: Medicine
Language: English

This journal is Open Access

About

Medical Journal of Babylon (MJB) is a quarterly medical journal concerned with clinical and basic medical researches. MJB follows the Publication Ethics Statements suggested by Committee on Publication Ethics (COPE) and International Committee of Medical Journal Editors (ICMJE).

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العنوان البريدي: العراق-محافظة بابل- الحلة –ص ب 473 جامعة بابل –كلية الطب – مجلة بابل الطبية
عنوان البريد الالكتروني medjbabylon2004@gmail.com

Table of content: 2008 volume:5 issue:3-4

Article
Evaluation of ponseti method in treatment of congenital idiopathic clubfoot

Authors: Adel H.Al-hindawi
Pages: 325-329
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Abstract

Idiopathic congenital talipes equinovarus is the most common deformity of the foot. we report our initial experience in using ponseti method for conservative treatment of club foot .we studied 42 patients with 62 club feet from July 2002-to-december 2006-in orthopaedic clinic in Al-Hilla teaching hospital and in private clinic, age from 1 st day to 10 months ,by serial correction and casting (2-8 times, for 7-10 days in each times).tendoachilles tenotomy is used in 6 cases only(with local or general anesthesia),with follow up after treatment for one year, four patients(6feet were lost from follow up) . we achieve 82% success rate, failure of correction is mainly related to poor compliance of the patients to the cast , late presentation of the patient to the orthopaedic clinic, and the severity of deformity is the third cause. Complications are only 5 cases including, fore foot swelling, cast slippage and skin necrosis, all complications are treated. We think that ponseti method is a safe and effective treatment for congenital idiopathic club foot and decreases the need for extensive surgical correction.

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Article
BURN TRAUMA IN BABYLON

Authors: Mohammed B. Hatif
Pages: 330-334
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From Feb. 1999 to Feb. 2001, There were 1000 patients to be treated for burn in Hilla Surgical Teaching Hospital burn unit in Babylon. -596 male patients (59.6 %), 404 female (40.4 %). -66o (66%) of cases were children, young adults 330 (33%), and old age group form 10 (1%).The vast majority of cases fall in the group of moderate to major burns. Flame burn formed 653 (65.3 %), 332 ( 33.2 % ) cases hotliquid ,and 15 (1.5 % ) sustained electric burn .-100 patients (10 %) treated surgicaly.Hospital stay extended from 1-12 weeks.Bacterial study showed 54% psuedomonas, staph. Aureus 22%, Klebsiella 13 %Proteus 9 % and E coli 2 %,175 patients died due to : - inhalation injury 55%, septicemia 44%, G. I. bleeding one case. The study has shown the burn injury problem as amajor national health problem , and prolonged morbidity and temporary or perminant disability associated with it to result in astaggering economic drain on social resources and finantial support is required.Prophylaxis against burn is better than treatment.Teamwork approach to burn care is found to be of great importance.This study can be regarded as amessage to whome it may concern.

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Article
Spinal Hydatid disease in Iraq "endemic area”

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spinal hydatid disease is rare, even in endemic areas that considered hydatid disease a significant problem. Twelve cases of spinal hydatid were presented, and their management discussed. The authors reviewed most of the recent literatures and proposed a simple classification for hydatid lesions in the spine. The study stressed on consideration of this disease in the differential diagnosis of backache and spinal cord compression in endemic areas before surgical intervention so that measures can be taken to decrease complications and rate of recurrence.

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Article
BURN TRAUMA IN BABYLON

Authors: Mohammed Brisam Hatif
Pages: 343-346
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From Feb. 1999 to Feb. 2001, There were 1000 patients to be treated for burn in Hilla Surgical Teaching Hospital burn unit in Babylon. -596 male patients (59.6 %), 404 female (4o.4 %). -66o (66%) of cases were children, young adults 330 (33%), and old age group form 10 (1%).The vast majority of cases fall in the group of moderate to major burns. Flame burn formed 653 (65.3 %), 332 ( 33.2 % ) cases hotliquid ,and 15 (1.5 % ) sustained electric burn .-100 patients (10 %) treated surgicaly.Hospital stay extended from 1-12 weeks.Bacterial study showed 54% psuedomonas, staph. Aureus 22%, Klebsiella 13 %Proteus 9 % and E coli 2 %,175 patients died due to : - inhalation injury 55%, septicemia 44%, G. I. bleeding one case. The study has shown the burn injury problem as amajor national health problem , and prolonged morbidity and temporary or perminant disability associated with it to result in astaggering economic drain on social resources and finantial support is required.Prophylaxis against burn is better than treatment.Teamwork approach to burn care is found to be of great importance.This study can be regarded as amessage to whome it may concern.

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Article
EVALUATIVE STUDY FOR THE BIOCHEMICAL & PHYSIOLOICAL EFEECTS OF ORAL CONTRACEPTION IN IRAQI WOMEN

Authors: HUDA M.SHACKER
Pages: 347-364
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Abstract

Objective: This is study to evaluate the effects of combined oral contraception, low esterogen type on some liver function , other physiological and biochemical charecterstics of the blood. Study design&Setting: prospective b study atBabylon medical college teaching maternity hospital,Department of Obstetric s& Gynecology,from july 2006 to june 2007. Materials&methods: the study enrolled 330 women ,attending family planning center of the hospital. They were divided into 2 groups, The study group of 250 women ( they were all pills usres for a variable time), the control group of 80 healthy women ( were using natural methods of contraception),Liver enzymes ALT,ALP, serum bilirubin , serum cholesterol, blood sugar , blood pressure, body mass index were compared between both group , statistical analysis was carried out using student t test, p value was calculated , any value more than 0.005 was considered not significant. Results: The study revealed: Ahighly significant (p0.005) when compared with the control group, There was ahighly significant reduction ( p< 0.01) in HDL in the study group when compared with the control group. There was ahighly significant elevation ( p<0.01) in total cholesterol for the study group when compared with the control group. There was apositive correlation but it was non significant between the total cholesterol, HDL level ( R=0.2, P=0.001). There was also ahighly significant elevation ( p<0.01) in the glucose level in the study group, and there is apositive correlation between the mean glucose and total cholesterol in the study group. There is a significant increase (P

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Article
Isolation and characterization of Raoultella ornithinolytica from Clinical Specimens in Hilla City

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A total of 720 clinical samples were collected from three main hospitals in Hilla city/ Babylon province. Samples were screened for the presence of Raoultella spp., as well as studying their expression of virulence factors. A total of 144 bacterial isolates were recovered and identified as Klebsiella-like organisms. Out of these, 11 isolates were identified as Raoultella ornithinolytica, which represent 7.6% of all Klebsiella-like organisms found. Many virulence factors expressed by R. ornithinolytica were studied in vitro. All isolates produced capsule and expressed CFA/I, and CFA/III. Nine isolates (81.8%) were able to produce siderophores. Four isolates (36.6%) were able to produce bacteriocin. All R. ornithinolytica isolates were unable to produce extracellular protease, hemolysin, and histamine. All isolates of R. ornithinolytica were resistant to penicillin, ampicillin, gentamicin, chloramphenicol, rifampin, cephalothin, cephotaxime, streptomycin, amoxicillin.,but they showed high sensitivity to nitrofurantoin and ciprofloxacin, and all them were completely sensitive to meropenem. R. ornithinolytica expressed a high degree of sensitivity to the effect of human serum when they grew in human serum at 37 o C for 3 hrs. The present study represented the first record of occurrence of R. ornithinolytica in human clinical samples in Iraq.

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Article
Probiotic effects of feeding live Lactobacillus acidophilus to Candida albicans-colonized oral cavity of rats

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This study investigates the antagonism activity of Lactobacillus acidophilus against the yeast Candida albicans in vitro. Results revealed that L. acidophilus with high antagonism activity and inhibited growth of C. albicans. Amodel for oral candidiasis in BALB/c rats was established . After inoculation with 1×10 8 C. albicans yeasts, these rats displayed increased levels of oral colonization , oral thrush appeared after 4 days of infection . Rats were fed live L. acidophilus for assessing its capacity to control the oral infection by elimination the yeast from the oral cavity. Data showed that feeding live L. acidophilus for 15 days significantly shortened the duration of oral colonization compared to control animals.

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Article
Etiologic agents of Bacteremia among Newborns in Hilla City

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A prospective study was carried out on 304 cases of bacteremia in newborn less than one year of age with fever. Cases of gastroenteritis, respiratory tract infections, and suspected sepsis in children seen or admitted to the Babylon Maternity and Children Hospital in Babylon Province - pediatric wards were studied from October /2007 to March /2008. Clinical and microbiological data were recorded in a questionnaire or obtained from patient medical records. Most of the newborn with bacteremia (78 %) were less than 12 months old. After culturing the blood samples the results indicated that 240(78%) blood samples revealed positive cultures consisting of 166 (69.2 %) Gram-positive bacteria isolates and 74 (30.8 %) Gram-negative isolates, represented by Streptococcus pneumoniae consist of 36.7%, Staphylococcus aureus accounted for 18.1%, Viridians streptococci 14.5%, Staphylococcus epidermidis 13.3%, Streptococcus spp. 7.2%, Bacillus spp. 6% and Clostridium spp. 4.2% and Gram negative bacteremia causes represented by E. coli 40.5%, Pseudomonas aeruginosa 20.3%, Salmonella typhi 16.2%, Acinobacter 5.4%, Proteus vulgaris 2.8%, Haemophilus influenzae 4% and Klebsiella pneumoniae 10.8%, major infections of bacteremia in Newborns was in age between 1-8 months, consisting of 77%. The rate of infection in newborns living in rural area was found to be (62.1%) while it was (37.9%) in urban newborns. The rate of infection with bacteremia in newborns feeding on breast was found to be (25.4%) while it was (74.6%) in newborn whom artificial feeding newborns.

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Article
A simplified method for DNA extraction from human blood clot: A familiarized diagnostic tool in forensic analysis

Authors: Israa Adnan Ibraheam --- Sahib Ahmad --- Muhammed Baqur
Pages: 395-399
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We have simplified the conventional techniques used to extract DNA from clotted blood by salting out technique, in such away some simple chemical treatments (SDS and NaCl) of cellular lysate of clot substituted the hazardous organic solvents such as phenol. Distilled water played an important role in eliminating almost all RBCs contaminating the specimens. Differences were not identified between clotted blood procedure and non-clotted blood procedure. Therefore, this method might be used in routine clinical laboratories for forensic analysis such as finger printing and other tests.

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Article
Evaluation of ponseti method in treatment of congenital idiopathic clubfoot

Authors: Adel Hassan Ali al-hindawi
Pages: 400-404
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Abstract

Idiopathic congenital talipes equinovarus is the most common deformity of the foot. we report our initial experience in using ponseti method for conservative treatment of club foot .we studied 42 patients with 62 club feet from July 2002-to-december 2006-in orthopaedic clinic in Al-Hilla teaching hospital and in private clinic, age from 1 st day to 10 months ,by serial correction and casting (2-8 times, for 7-10 days in each times).tendoachilles tenotomy is used in 6 cases only(with local or general anesthesia),with follow up after treatment for one year, four patients(6feet were lost from follow up) . we achieve 82% success rate, failure of correction is mainly related to poor compliance of the patients to the cast , late presentation of the patient to the orthopaedic clinic, and the severity of deformity is the third cause. Complications are only 5 cases including, fore foot swelling, cast slippage and skin necrosis, all complications are treated. We think that ponseti method is a safe and effective treatment for congenital idiopathic club foot and decreases the need for extensive surgical correction.

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Article
The Effect of N-Acetylcysteine (NAC) on bacteria isolated from Patientswith Chronic Obstructive Pulmonary Disease (COPD)

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Twenty patients with COPD have been included in this study who were admitted at Mirjan teaching hospital for Internal medicine, where the disease diagnosed by the physicians according to the criteria of chronic bronchitis with productive cough in a period of three successive months in each of two consecutive years in absence of identifiable causes of sputum production with their age group ranged from 45 up to 86 years at a period from January up to February 2007. N-acetylcysteine was performed to detect its effect on the growth of twenty bacterial isolates, 90% of these isolates had no growth in the presence of this material, whereas, 10%gave positive growth even in the presence of this substance.

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Article
Bacteriological assessment of water samples obtained from water supplies of Babylon hospital for Gynecology and Paediatrics

Authors: Ashwak A.A.Al-Khafaji
Pages: 410-414
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In this study 128 tap water samples from 14 sites in Babylon hospital for gynecology and pediatrics being obtained. The results of bacterial investigations have showed that all water samples are free from any pathogenic bacteria, however certain bacteria which are considered as contaminants, non harmful bacteria,were isolated such as Lactobacillus and Micrococcus.Chlorine conce- tration is detected in all water samples and it was seen that chlorine concentrations were ranged from (1.2-1.6 ) P.P.M.

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Article
The immune functions and immune profiles of human bacterial persistent pyuria

Authors: Baha. H. H. Al- Amedi --- Ibrahim. M.S. Shnawa
Pages: 415-422
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One hundred twenty five uropathy patients were with clinically proven persistent pyuria (PP). Bacterial culture studies for their clean catch midstream urine samples showed that they were of bacterial causes (BPP). Mucosal and serum globulin concentrations, specific agglutinins and mucosal as well as peripheral leucocytes inhibition index were made to these patients. Results of these immunologic investigations have shown, that the associated bacterial uropathogens (ABUs) were of both gram negative and gram positive types. These ABUs may have one or more than one of the antigenic epitopes. The patient immune responses were dependent on the nature of the immunodominant epitope of the antigen. Thus antibody responses may be scored alone or antibody and cell mediated responses can be scored among these patients. Immunocompromy, no matter of its origin reduce the outcome of the immune function . Five immunoprofiles were deduced as; Profile I: The infection stimulate mucosal and systemic humoral and cellular immune responses. Profile II: The infection stimulate mucosal and systemic humoral immune rcsponses. Profile III: The infection stimulate reduced mucosal and systemic humoral and cellular immune respones. Profile IV: The infection stimulate low grade mucosal and systemic humoral immune responses. Profile V: The aetiogen nonrecoverable with low globulin levels.

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Article
Study of phagocytosis in diabetic patients

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This study deals with the host resistance to infection in diabetes and the influence of an acute infection on the endocrinologic- metabolic status of the diabetic patient, while it is well known that acute infection lead to defecting in controlling blood sugar levels and that infection is the most frequently documented cause of ketoacidosis. The patient with diabetes mellitus are more susceptible to infection than age and sex matched non diabetic subject “the data were being studied as phagocytic activity or (leucocytes function) to ingest bacteria (This study consist of 72 diabetic patients and 19 apparently healthy individuals. These samples in this study have been grouped according to the severity of diabetes, duration of disease , insulin non insulin dependant, controlled and noncontrolled for all patient and control sample. Phagocytic activity is done as well as bacterial cells per neutrophil and rate of ingestion of phagocytic cells to the bacteria among time of incubation). The result among 72 diabetic patients showed a highly significant decreased(P<0.01) in phagocytic activity of neutrophil among this patients and direct correlation between the phagocytic activity of polymorphonucleur neutrophil (PMN) (P< 0.05) and the mean glucose level after comparsim with the control samples. The effect of duration of disease give a highly significant differences (P< 0.01) with the phagocytic activity after comparism with control group as well as less than 5 years and more than 5 years. There is a significant diminution in phagocytosis of staphylococcus aureus in subject poorly controlled diabetes in comparism with the control group. The result from these study suggest that good control of blood sugar in diabetic patient is a desirable goal in the prevention of continuous infection (Bacterial, Viral, Fungal….etc) and to ensure maintenance of normal host defense mechanism that determine resistant and response to such infections.

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Article
Parasitic etiology of newborn gastroenteritis in Babylon governorate

Authors: Raad A. Kadhim --- Ali Hussain M. Al-Marzoqi
Pages: 501-506
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In the present study, 173 children stool specimens less than 12 months of age suffering from diarrhea collected in suitable clean containers and examined firstly macroscopically and then microscopically from Babylon hospital for children and maternity from January/2008 to May/2008. Presenting acute diarrhea was examined to identify associated parasitic Enteropathogens agents. Parasitic causes formed (56%) from all cases represented by; Entamoeba histolytica 41.2%, Ascaris lumbericoides 32%, Giardia lamblia 18.6%, Trichuris trichura 6.2% and Hymenolepis nana 2%. Parasitic infections in rural newborn revealed (68%) higher than urban cases (31.9%), Parasitic infections with breast feeding are less infected than whom artificial depending feeding (42.2%) and (57.7%) respectively. Most parasitic infection like Entamoeba histolytica, Ascaris lumbericoides, Giardia lamblia and Trichuris trichura was higher in patients aged from (9-12 months) formed 70%, 64.5%, 55.5% and 100% respectively.

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Article
H. pylori as a risk factor for IHD in male at Hilla province

Authors: Osama .F. Al-Jubori --- Amir .S. Al-Mumin
Pages: 507-514
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In the present study the aim was to determine whether there is an association between H. pylori infection and IHD or not , which was demonstrated in Hilla province patients, thirty male patients admitted to c.c.u. complaining of acute MI Their Age range ( 35 – 45 ) was estimated for anti H. pylori antibodies in their sera with thirty healthy persons as control . The study revealed that twenty one patients with acute MI shows positive test for anti H. pylori antibodies while only nine of them shows negative test, using a chi square statistical method we found a significant association of H.pylori infection with IHD ( P<0.05), in relation to control. The sensitivity of the test in general 70 % while the specificity is 30 % , using percentage and according to the type of MI , ant MI shows the highest percentage (50%) while the lat. MI shows the lowest percentage (3.3%).suspect to idea of possible relation of site of myocardial infarction with H. pylori infection.

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Article
Study of Nonspecific Cellular Immune Function (Leucocytospermia) on Asthenozoospermic , Oligozoospermic & Azoospermic Infertile Patients

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Many studies had been established to detect the affects presence of leucocytes on semen quality and sperm function tests . Than after their effects on men fecundity. This study had been occure on infertile (48) asthenozoospermic , (18) oligozoospermic & (13) azoospermic patients as well as to (10) control subjects . Results study of this work obvious that presence of leucocytes in seminal fluid can be explained as : 1-Inflammatory response . 2- Nonspecific cellular immune response . 3- Cooperation and / or inverse cooperation of natural and adaptive Immune responses to foreign antigenic epitopes.

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Article
Incisional local anesthesia for pain control after abdominal surgery

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Bach ground:-The optimizing of postoperative pain control is an important aspect in perioperative patient care the use of inscional local anaesthesia in post operative pain control after abdominal operations was proved effective method of analgesia Aim:-to evaluate the efficacy of postoperative incisional infusion of local anaesthesia (bupivicain) in reduction of postoperative pain in abdominal surgical wounds as well as the need for systemic analgesia and possible side effects of local anaesthesia. Patients and method:- aprospective randomized placebo controlled clinical trial on 80 patients (39 male 41 female) between 13 –54 years old of different abdominal operations, admitted to El- furat hospital in kufa city from December 2005 to October 2006.The patients were divided in tow groups, intervention group 40 patients and placebo group: 40 patients. The study involve the use of incisional intermittent injection of local anesthesia bupivacaine 0.25% via thin subfascial catheter ( B/BRAUN Melsungen AG), in intervention group , for relieve of postoperative pain and assess need for systemic analgesia ( especially opiate) as compared to placebo group in which we inject normal saline via the incisional catheter. Result:-The study had been discusses age, sex distribution, types of incision, pain assessment by visual analogue score, the need for systemic analgesia & complications of local anesthesia. The mean visual analogue score of pain was measured in 1 st 6 th , 12 th , 18 th , 24 th hours after surgery in every patient in both groups were significantly decreased in bupivacaine group in comparism to normal saline group P<0.005. There is significant decrease for systemic analgesia requirements after operation in intervention group as compared with placebo group (P<0.05). There is only one minor complication (seroma or wound infection) was reported in each group (2.5%). Conculsion:-Study concludes the effectiveness of incisional bupivacaine intermittent injection in relieve of postoperative pain and decrease need for systemic analgesia. Key words: incisional local anesthesia, abdominal surgery.

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Article
Civilian and non-civilian leg injuries in Iraq before and after Iraqi ´freedom`

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Aim of study: To compare civilian and non-civilian leg injuries (fractures and soft tissue injuries) in patients admitted to the orthopedic ward in Al-hilla general hospital in peace and war times. Methods: A retrospective study of patient's records in two periods: from 1 January 2002 to 31 August 2002 and from 1 January 2005 to 31 August 2005 taking into consideration patient age, sex, type of injury, mechanism of injury, associated neurovascular injury, associated other limbs and body parts injuries, type of operations, and length of stay. Results: In the peace period there were 30 patients vs. 176 in the war period. The rate of civilian injuries has been duplicated 2x, while that of non-civilian 60x: 60% of them were minor fragment injuries; 89% of open fractures were Gustillo П &Ш; 68% of open fractures were stabilized definitely by external fixator. The rate of amputation in the " freedom" period has been duplicated 12 x. Conclusion: Increased violence in Iraq following `freedom´ with the occurrence of the ever seen before terror attacks has resulted in many massacres among innocent Iraqi civilians. These disasters, in view of limited medical care facilities in our hospitals, create many problems that partly should be solved by organized and accurate triage.

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Article
The Behavior of the Plasma Homocysteine and Selenium Concentrations in Patients with Acute Myocardial Infarction
سلوك مستويات الهوموسيستين والسيلينيوم في بلازما دم المصابين باحتشاء العضلة القلبية الحاد

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Background: Increased concentrations of plasma total homocysteine and decreased concentrations of plasma selenium are separately associated with cardiovascular disease. Objective: Investigate the correlation between plasma total homocysteine and selenium in patients with acute myocardial infarction (AMI). Methods: Patients of present study was thirty nine men with AMI admitted to Marburg Hospital in Marburg city, Germany on 2007. Plasma total homocysteine was determined using HPLC. Plasma selenium was determined using atomic absorption spectrometry. Results: Plasma homocysteine of patients found to be increased, whereas plasma selenium found to be decreased when compared with reference range . The correlation between plasma homocysteine and selenium found to be negatively correlated. Conclusion: The negative correlation between plasma tHcy and selenium may indicate that they have a significant impact on the process of atherogenesis. The change in the levels of plasma total homocysteine and plasma selenium might be result from oxidative stress associated with AMI.

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Article
Early Transbdominal Trans peritoneal Omental flap repair for vescovaginal sistula

Authors: Emad Hassan Mahmood
Pages: 551-555
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Aim of the study : To evaluate patients selection for early of vesicovaginal fistula by transbdaminal transperitoneal approach with omental flap interposition . Patients and methods :twenty four female patients with vesicovaginal fistula underwent repair by transabdminal transperitoneal approach in Al-Hilla Teaching hospital department of urology between 2000-2006 their ages between 23-45 years , the cause of the fistula was cesarean section in 20 patients (83.8%) and 4 patients (16.2%) the cause was hysterectomy . Results : The indications for cesarean section were midwife interference in 16 patients , were rupture uterus identified , other indications were placenta previa 2 patients , fetal distress 1 patient and previous cesarean section in 1 patient , while the indications for hysterectomy were dysfunctional uterine bleeding in 3 patients and big uterine fibroid in 1 patient . Over all success rate were 22 patients (88.3%) had successful repair with only 2 patients (11.7%) were failed. Conclusion : Early repair of vesicovaginal by the transabdominal transperitoneal omental flap give good results in patient with first time fistula and no vaginal infection present and inflammatory process at fistula site has resolved.

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Article
Echocardiographic evaluation of Cardiac Involvement in Myeloproliferative Disorders

Authors: Hassanain H.Hassan --- Alaa S.Alawad --- Nabeel S.Murad
Pages: 556-574
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Thromboembolic events are common cause of death in patients with myeloproliferative disorders (MPD) especially those with cardiac involvement . In previous studies, cardiac involvement, including coronary arterial thrombosis, myocardial infarction, pulmonary hypertension (PHT), asymptomatic pericardial effusion, cardiac tamponade, intractable cardiac failure due to intraventricular thrombosis, and stenosis of aortic, mitral valves, even requiring surgical treatment had been reported in MPD This cohort study was carried out in three Iraqi teaching hospitals for Medicine including Al-Kadhimyya Teachginmg Hospital , Al-Yarmook Teaching Hospital (including National haematology Centre) and Merjan Teaching hospital in Babylon. The study groups were 26 patients (mean age female and male) with MPD and 30 age-matched healthy controls. MPD group included sixteen cases chronic phase chronic myelogenous leukemia (CML), two idiopathic myelofibrosis (MF) , seven polcythemia vera and one essential thrombocythemia . History regarding thrombotic and bleeding complications, examination and lab investigations are evaluated for these patients and transthoracic echocardiographic study was done for them and for the control subjects. The results are compared by statistical methods. Mitral regurgitations were present in 9 patients (34.6%) and two controls (6.7%) (P < 0.05). Aortic regurgitation were present in 3 patients (11.5%) and no control (0.00%) (p < 0.05%) . Rates of regurgitations of other valves were not different in-between MPD subgroups and control (P>0.05). The rates of annular calcifications and valvular thickening were not different between MPD and control groups. Pulmonary hypertension (PHT) was not detected in patients or control. Measurements of ejection fraction, fractional shortening of left ventricle, E/A ratio and aortic root dimension are significantly different between MPD and control (P<0.05). Left atrial dimension of patients with MPD was larger than controls (P>0.05). Left atrial dimension was the

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Article
Study of systemic cellular immune responses in smokers

Authors: Azhar Ammran
Pages: 575-578
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Phagocytic activity by using nitroblue tetrazolium reduction (NBT) and leukocyte migration inhibitory factor (LIF) were studied in thirty health persons (20 smokers and 10 in nonsmokers ) .Blood with anticoagulant were collected from them and used to study NBT and LIF .The results found that there is no significant differences between smokers and nonsmokers in NBT test . The main of LIf in smokers was 0.528 while in nonsmokers was 0.86 and high significant differences at level P < 0.05.this study found that smoking effect on specific cellular immune response but no effect on innate immune response

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Article
Etiology and Antimicrobial Sensitivity of Common Uropathogens in Hilla Infants

Authors: Ali H. Al-Marzoqi
Pages: 579-586
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In this study, 100 febrile infants suffering from Urinary tract infection (rectal temperature > 38°C) who presented to the Pediatric Clinic or Emergency Department of Babylon Maternity and Children Hospital from February2008 to June2008 underwent a history and physical examination. In this study, Escherichia coli formed the major causative agent (49%) followed by Pseudomonas aeruginosa (25%), Klebsiella pneumoniae (18%) and Proteus species (8%). E. coli isolates showed sensitivity to Amikacin, Chloromphenicol, Nitrofurantoin, Ofloxacin, Norfloxacin, while Pseudomonas aeruginosa shows sensitivity with Norfloxacin, Ofloxacin, Piperacillin, Tobramycin, Proteus species shows sensitivity with Amikacin, Amoxicillin , Cefodizime, Cefoxitin, Cephalexin, Gentamycin, , Norfloxacin, Piperacillin, Tobramycin and Klebsiella pneumoniae isolates shows sensitivity with Amikacin, Norfloxacin, Piperacillin, Tobramycin. Our investigation showed that from the 100 febrile infants with UTI, 57 had pyuria > 5 WBCs/hpf, 90 had pyuria >10 WBCs/mL, 77 had CRP >24 mg/L, 82 had ESR >35 mm/hour, and 44 had WBC >15 000/mL.

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Article
Study of Gram Positive Infantile bacteremia using some Physiological markers and Antibiotics Susceptibility patterns

Authors: Ali H. Al-Marzoqi
Pages: 587-594
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130 blood samples were obtained from febrile infants who admitted to Babylon Maternity and Children Hospital during the period from February 2008, until June 2008. This study investigated the distribution and the most causative agents (Gram Positive Bacteria), the elevation of (CRP, ESR and WBCs count) with the infections and antibiotic susceptibility patterns of bacterial pathogens isolated from patients with bacteremia. Results showed that Staphylococcus aureus formed (57%) from all bacteremia causative agents followed by Streptococcus pneumoniae (32.3%) and Bacillus spp. (10.7%). Staphylococcus aureus showed sensitivity for Amikacin, Nitrofurantoin, Norfloxacin and Ofloxacin, while Streptococcus pneumoniae were sensitive to Amikacin, Amoxicillin, Cefodizime, Chloromphenicol, Clarithromycin, Gentamycin, Kanamycin, Lincomycin, Nitrofurantoin, Norfloxacin, Ofloxacin, Oxacillin, Oxytetracyclin, Penicillin and Rifampim, Bacillus spp. Revealed sensitivity with Amikacin, Chloromphenicol, Gentamycin, Kanamycin, Nitrofurantoin, Norfloxacin, Ofloxacin, Piperacillin, Tetracycline, Tobramycin and Vancomycin. From 130 infants with bacteremia 88 had C-Reactive Protein >24 mg/L, 82 had ESR >35 mm/hour, and 73 had WBC >15 000/mL.

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Article
Sensitivity , Specificity and predictive values of ultrasonography in the diagnosis of acute appendicitis

Authors: Kassim Amir Hadi Taj-Adean
Pages: 595-604
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objective: To evaluate the sensitivity and specificity, negative predictive value (NPV), and positive predictive value (PPV)of ultrasonography (US) in the diagnosis of acute appendicitis. PATIENTS AND METHODS A cross sectional study of 125 patients with suspected appendicitis was performed .. The appendiceal diameter (normal, less than 6 mm), compressibility of the appendix ,intraluminal fluid and echogenicity of surrounding fat were the primary criteria used to determine the status of the appendix by ultrasound and compare with histopathological examination as confirmative test RESULTS: The prevalence of real confirmed appendicitis by histopathology examination is 46% .while the sensitivity of sonographic examination in detecting appendicitis is 85%, the specificity is 53%, . The positive predictive value of sonography is 60 %; while the negative predictive value is 81%.The most accurate appendiceal finding for appendicitis was a diameter of 6 mm or larger 95% while 81% of confirmed cases have lack compressibility while only 28% of confirmed cases of true appendicitis have intraluminal fluid . CONCLUSION: Sonography is useful in detecting acute appendicitis and can clearly show the abnormal appendix more frequently .with high sensitivity and low specificity

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Article
The Rule of Degital Rectal Examination and Prostatic Specific Antigen in Diagnoses of Prostate Carcenoma

Authors: Muhammad Redah Judi
Pages: 605-610
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Abstract

25 treated in urology department in al hilla teaching hospital in a period 2004-2007 all of them had prostatic nodule, all of them send for PSA ,and all of them undergone prostatic biopsy from the nodule only 15 patients had prostatic carcinoma, 6 patients had BPH, 4 patients had chronic non specific nodule. 17 patients of all suspicious DRE had PSA more than 10ng/ml, an 5patients had PSA range 4ng/ml to less than 10ng/ml , and only 3 patients had PSA less than 4ng/ml. 12 patients from a patients with carcinoma of prostate had PSA more than 10ng/ml , tow patients with prostate carcinoma had PSA (4-10ng/mle), only one patient had PSA less than 4 ng/ml. So we must recommend combination of PSA and DRE in diagnoses of prostatic carcinoma.

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Table of content: volume:5 issue:3-4