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مجلة ذي قار الطبية

ISSN: 19929218
الجامعة: جامعة ذي قار
الكلية: الطب
اللغة: English

This journal is Open Access

حول المجلة

مجلة ذي قار الطبية, تصدر من كلية الطب / جامعة ذي قار. تأسست في سنة 2002, تهتم بالابحاث العلمية والطبية

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معلومات الاتصال

Email: thi_unv_medi@yahoo.com

جدول المحتويات السنة: 2011 المجلد: 5 العدد: 1

Article
Effect Of Brca1 After Uv-B-Irradiation In Cell Cycle Progression Between Human Melanoma Cell Lines Determined By Flow Cytometer
تأثيرا لجين المسوؤل عن سرطان الثدي بعد التعرض لأشعة فوق البنفسجية(ب) في تعاقبِ دورةِ حياة الخليةِ لخلاياِ الورم ألقتامي لاانسان قدرت بطريقة الفلوسايتومتري.

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الخلاصة

The aim of the current study was to evaluated the effect of BRCA1(breast cancer 1 early-0nsent) after UV-B-irradiation in a panel of human malignant melanoma cells using flow cytometry method. Different human melanoma cell lines (SK-MEL28,SK-MEL93, ,SK-MeL93/shBRCA1 and SK-Mel93/shplKO.1) were cultured for triplicaten experiments. Cells were exposed to UV-B (10mJ/cm2)for different point time(1/2,1,3,6,9,12,and 24h). Cells at 0hr were a non-irradiation control. The cell cycle was evaluated by flow cytometry. SK-MEL28 cell line seemed to be synchronized at the G1/S boundary phase until 12h after UVB-irradiation. a decrease in the fraction of S cells and a reciprocal increase of cells in Sub-G1 phase was observed , from 12 to 24h.While, the SK-MEL93 a rapid increase (about 35%) of cells in Sub-G1 phase was observed already 6h after UVB irradiation. Moreover, we found that the SKMel93/shBRCA1 cells seemed an increase (about 15%) of cells in Sub-G1 phase already 12h after UVB irradiation compared with cells infected with the empty lentiviral vector (SK-Mel93/shplKO.1). we conclude that an important role played by BRCA1 providing new insights into the molecular mechanisms underlying UV-induced melanomagenesis

الكلمات الدلالية


Article
Explorative Laparotomy Versus Conservative Management In Acute Pancreatitis
مقارنة بين العلاج التحفظي وبين فتح البطن في التهاب البنكرياس الحاد

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الخلاصة

BACKGROUND Acute pancreatitis is common disease, the two major etiological factors responsible for acute pancreatitis are alcohol and cholelithiasis . Patients and methods This study was done in the emergency department (ED) in AL- Hussein. teaching- hospital ( Al Nassyria ) during 2 years (between 1st junuary 2009 to 31st December 2010) about 39 patients presented as acute abdomen proved later on as acute pancreatitis , all patients were presented to the emergency department with acut abdominal pain .19 patients had reports suggested that they had features suspected perforated viscus[a history of more than 72 hours of sever abdominal pain with abdominal distention,free fluid in the peritoneal cavity] so their conditions were mandated exploratory laparotomy . While the other ( 20 patient ) had less feature of abdominal distention, not dehydrated and near normal vital sign so they were postponed to the early morning and re-evaluated by C.T scan of the abdomen and complete evaluation of Ransons criteria which confirm that they had a cute pancreatitis and treated conservatively. Aim of study Comparison between conservative versus operative management in acut pancreatitis. Results Patients in group 1 (Conservatively managed patient ) required relatively less hospital stay than the patient in group 2 (explored patient),but complications like pseudo cyst of pancreas,bilateral pleural effusion occurs mores in group 1. Conclusion Early washout of abdominal cavity by explorotive surgery or other minimal access pruceduers was advocated in management of acute pancreatitis.

الكلمات الدلالية

Acut pancreatitis --- conservative vs operative management


Article
The Role Of Pcr Amplification Of 16s Rrna In Early Diagnosis Of Neonatal Sepsis
دور البي سي ار في التشخيص المبكر لخمج الطفال الرضع

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الخلاصة

Neonatal sepsis is a major cause of death in newborns despite sophisticated neonatal intensive care. This cross-section study was done on 69 neonates with suspected sepsis who were admitted in Neonatal Intensive Care Unit (NICU) of Maternity and Child Teaching Hospital at AL-Diwaniya city, and 20 healthy neonates as a (control group) in the period from March to October 2009.This study was conducted to evaluate the diagnostic value of polymerase chain reaction (PCR) for bacterial DNA component encoding 16S rRNA in the early diagnosis of neonatal sepsis prior to the blood culture ( the golden standard test). The investigation protocol included blood culture and 1 mL of venous blood for molecular analysis by polymerase chain reaction (PCR) for bacterial DNA component encoding 16 s RNA in all cases, We compared the results of PCR with blood culture. The culture positivity rate 20 (28.9%) among suspected sepsis neonates, with sensitivity of (29%)and specificity of(100%).The male more affected than female among proven sepsis with ratio 3:2. It was found a high sensitivity (100%), high specificity (87.5%) and positive predictive value of (98.6), negative predictive value of (100%)for PCR analysis for bacterial DNA component encoding 16S rRNA .Blood culture is the most reliable method for diagnosis of neonatal sepsis. Polymerase chain reaction is useful and superior to blood culture for early diagnosis of sepsis in neonates.

الكلمات الدلالية


Article
Glycaemic Control In Diabetes Mellitus
السيطرة الأيضية عند مرضى السكر

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الخلاصة

Objective: To evaluate the degree of glycaemic control among diabetic patients. Methods: The study included 156 diabetic patients (64 with insulin – dependent diabetes mellitus (IDDM) and 92 with non insulin – dependent diabetes mellitus ( NIDDM) ), and 120 control subject. The parameters measured were fasting blood glucose (FBG) and the level of glycated haemoglobin (Hb A1c). Results: HbA1c level was significantly higher among diabetic patients (both IDDM and NIDDM) compared to controls (P<0.001). Also, 43.8% of IDDM patients and 63.0% of NIDDM patients were in poor glycaemic control. Conclusion: substantial proportion of diabetic patients are in poor metabolic control , and hence, more prone to early diabetic complications.


Article
Reduction Of Inferior Turbinate By Radiofrequency
اختزال المحارة السفلية للأنف بواسطة جهاز الترددات الراديوية

المؤلفون: Dr.Shamil A. Hilal د. شامل عبود هلال
الصفحات: 30-34
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الخلاصة

Objective : A prospective study was done at the period of 3rd July2009 - 4th Seb.2010 to see the effectiveness of radiofrequency in inferior turbinate reduction regarding nasal obstruction,morning sneezing , snoring, headache and nasal discharge. Method : Thirty-seven patients had been underwent radiofrequency turbinate reduction under local anesthesia and follow up them regarding their complaints. Results : We found that radiofrequency inferior turbinate reduction is very simple, effective, and relatively complication free as out patient procedure. Conclusion : Radiofrequency for inferior turbinate reduction can be held as outpatient procedure with minimal time & relatively simple cost and give the same results as other procedure that held to reduce the inferior turbinate bulk . So it is preferable over them when the equipments are available.

الكلمات الدلالية

radiofrequency --- inferior turbinate reduction


Article
Study Of Oxidant-Antioxidant Status In Recurrent Spontaneous Abortion
دراسة حالة الجهد المؤكسد و المواد المقاومة للتأكسد لدى النساء الحوامل اللواتي يعانين من إسقاط الحمل العفوي المتواتر

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الخلاصة

ABSTRACT Objective: To evaluate the association of oxidative stress and impaired antioxidant defense system with the occurrence of recurrent spontaneous abortion (RSA) . Study design : Case –control study consisting of 100 pregnant women with a history of RSA (study group) and 100 healthy pregnant women (control group) , their age ranging (15-45yr.) and both groups are classified into many subgroups according to maternal age , gestational age , parity and number of previous abortions . Fasting blood samples were collected and tested for measurement of serum vitamin C , vitamin E , albumin , oxidative stress biomarker malondialdehyde (MDA) and some essential trace elements (zinc and copper) by using spectrophotometric methods .Student t-test , chi-square and correlation analysis were used for statistical analysis . Results : Serum level of vitamin C , vitamin E , Cu and Zn were significantly lower (p<0.05) and serum level of MDA was significantly higher (p<0.05) in study group as compared with control group but no significant difference of serum albumin (p>0.05) between the two studied groups .Also no significant differences (p>0.05) of all measured biochemical parameters among different age , gestational age, parity and no. of abortions subgroups of patients (study group) except serum albumin, Zinc and Cu/Zn ratio were significantly changed in the last parity subgroup (>P5) as compared with (P1) for albumin level and with other parity subgroups of the same study group for Zinc and Cu/Zn ratio . While there was a significant increase (P<0.05) of MDA level in the (≥7 abortions) as compared with other no. of abortions subgroups of the study group . The linear regression analysis demonstrated a significant ( r=0.61 , 0.85 , 0.3 , 0.73 , 0.47 , p<0.05) negative correlation for vit.C , vit. E , Zn , Cu and Cu/Zn ratio respectively and significant ( r= 0.83 , p<0.05 ) positive correlation for MDA values with no. of previous abortions of study group . Also there is a significant ( r= 0.18 , 0.19 , 0.25 , 0.2 , p<0.05 ) negative correlation for vit.C , vit.E , Cu and Cu/Zn ratio respectively and significant ( r= 0.2 , p<0.05 ) positive correlation for MDA values with the age of pregnant females of both control and study groups . while there is a significant positive correlation (r=0.16, 0.18, 0.19 , p<0.05) of serum vit.C , vit.E and Zn respectively and a significant negative correlation (r=0.17, p<0.05 ) of serum MDA with parity in both control and study groups . Conclusions : Our data demonstrate that elevation of lipid peroxides (MDA) together with impaired antioxidant defense and status of trace elements and the presence of possible interrelationship between those parameters may be related at least partly to the pathogenesis of RSA .


Article
Alteration Of Trophoblastic Tissue Apoptosis And Their Role In Toxoplasmosis Induce Miscarriage
تغييرات موت الخلايا الفسلجي في النسيج المغذي للجنين (التروفوبلاست) ودوره في حث الإجهاض في داء المقوسات الكوندية

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الخلاصة

ABSTRACT: Toxoplasma gondii ( T. gondii) , a common protozoan parasite. T. gondii infection occurs worldwide and it is one of the most common infections in humans. The infection is mainly acquired by ingestion of undercooked or raw meat containing viable tissue cysts or by ingestion of food and water that is contaminated with oocysts shed by cats . In addition, it has been established that T. gondii can be transmitted from a recently infected mother to her fetus. During pregnancy the primary infection may lead to severe if not fatal complications for the fetus. These direct effects can lead to spontaneous miscarriage, stillbirth or congenital anomalies .apoptosis in villous trophoblast is increased in pregnancy complications such as Toxoplasmosis infection. From our study we found that Toxoplasma gondii downregulated apoptosis when caspase 3 and caspase 9 levels were investigated using immunohistochemistry technique . Aims of Study: So the aims of this search are to investigate the levels of Caspase 3 and Caspase 9 expression within T.gondii infected trophoblastic cells and their association with infection. Method: Fifty patients (aborted women), Their range age between (16 − 46) years, were included in this study. All patients sera were subjected to Enzyme Linked Immunosorbent Assay (ELISA) to detect specific Toxoplasma gondii IgM and IgG . In addition , trophoblastic tissues from the same patients were taken to confirm the infection of the T.gondii and to evaluate the expression of caspase 9 and caspase 3 using immunohistochemstry method. Results : Immunehiostochamical technique is more sensitive than ELISA in diagnosis of T. gondii when 18 patients were positive for Toxoplasmosis by immunohistochemistry While in ELISA only 16 patients were positive for specific anti – Toxoplasma IgM. The levels of Caspase3 and caspase 9 were downregulated in infected group. Conclusion : Caspase 9 expression and Caspase 3 expression are significantly highly decreased in women with spontaneous miscarriage in T.gondii positive group compared to patients control group indicating that Toxoplasma gondii downregulated apoptosis.

الكلمات الدلالية

Toxoplasma gondii --- apoptosis --- miscarriage


Article
Regular Physical Activity: Correlation With Conventional Cardiovascular Risk Factors
الفعالية البدنية المنتظمة: الترابط مع العوامل التقليدية القلبية الوعائية

المؤلفون: Dr. Salman K. Ajlan د. سلمان كاظم عجلان
الصفحات: 56-65
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الخلاصة

ABSTRACT Objective: To correlate regular physical activity (RPA) with conventional cardiovascular (CV) risk factors. Methods: In this study, 116 young adult males , 56 physically active and 60 physically inactive (sedentary), were included. Measurement of body mass index (BMI), basal energy expenditure (BEE) systolic and diastolic blood pressure (SBP, DBP ) and serum concentrations of fasting blood glucose (FBG), total cholesterol (TC) , triglyceride (TG) , low density lipoprotein-cholesterol (LDL-C), and high density lipoprotein-cholesterol (HDL-C) were performed. Results: Correlation and regression analysis revealed significant negative correlation of RPA with BMI (r: -0.414, P: 0.000), BEE (r: - 0.388, P: 0.000) SBP (r: -0.418, P: 0.000), DBP (r: -0.439, P: 0.000) ), FBG (r: -0.425, P: 0.000), TC (r -0.291, P: 0.002) , TG (r: -0.408, P: 0.000) , LDL-C (r: -0.305, P: 0.001), and significant positive correlation with HDL-C ( r :+0.430, P: 0.000). Conclusion: The study demonstrated a strong inverse relationship between RPA and CVD risk. Therefore, practicing moderate RPA is crucial to maintain healthy life and improve cardiovascular fitness, and this considerably reduces the future risk of CVD and its adverse clinical consequences.


Article
Doppler Evaluation Of Erectile Dysfunction In Diabetic Patient With Intracavernousal Alprostadil (Caverject®) Injection
تقييم الدوبلر لضعف الانتصاب في المرضى المصابين بالسكري باستخدام الحقن الجوفي بعقار البروستاديل

المؤلفون: Dr.Tayseer Ali Talab د.تيسير علي طلب
الصفحات: 66-75
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الخلاصة

ABSTRACT Objective: Erectile dysfunction (ED) is a common enough male problem. It is secondary to organic, psychogenic and combined causes. This study described the normal sonographic anatomy of the penis, sonographic technique for evaluation of ED and the normal phases of erection with intracavernousal injection (ICI) of alprostadil (coverject®). Patients and methods: Twenty five diabetic patients (on oral hypoglycemic drugs for at least 10 year) complaining of prolonged history (>2 years) of ED, aged 35 to 45 years, were included in this study. The treatment started with a minimal dose of 1.125 micrograms and the dosage was titrated to achieve rigid erection. Following the establishment of the effective dose, Doppler US examinations were performed. Results: 21 patients (84%) had a grade IV erectile response, the remaining 4 patients (16%)have grade III. A significant increase in peak systolic velocity between baseline and 20 µg PGE1 (p<0.001) was observed in all cases. Following ICI of Coverject there was a significant increase in grade of erection (p<0.001) and a significant reduction in the end diastolic volume (EDV) (p<0.001). A reduction of the EDV to below 5 cm s–1 was observed in all patients. Four patients with EDV <5.0 cm s–1 but >0.0 cm s–1 had poor erectile response following ICI while 21 showed persistent EDV reduction <5 cm s–1 with good rigidity. Conclusion: the important cause of ED in the diabetic patient is psycogenic factor and Intracavernous injections of Caverject are effective therapy for erectile dysfunction

الكلمات الدلالية


Article
The Use Of Avastin (Becacizumab) For The Treatment Of Diabetic Macular Edema In Iraqi Patients
دراسة استخدام الافاستين (بيفاسيزوماب) لعلاج وذمة الشائبة الصفراء للشبكية السكرية عند المرضى العراقيين

المؤلفون: Dr Salah Zuhair Al-Asadi د. صلاح زهير الأسدي
الصفحات: 76-83
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الخلاصة

ABSTRACT Purpose: To evaluate the effect of intravitreal bevacizumab on visual acuity in patients with diabetic maculopathy, clinically significant macular edema (CSME). Methods: Thirty eyes of twenty-eight patients (mean age, 57.9±13.8 years) with CSME were included in this study. Complete ophthalmic examination, including determination of best corrected visual acuity (BCVA), stereoscopic biomicroscopy with +90D lens was done at baseline and at each follow-up visit. All patients were treated with a 0.1 mL intravitreal injection containing 2.5 mg of bevacizumab (Avastin). Results: All patients completed 3 months of follow-up with a mean follow-up period of 5.26±2.39 months. The mean BCVA at baseline was 0.73±0.36 logMAR, which significantly improved to 0.63±0.41 (p=0.02), 0.58±0.36 (p=0.003), and 0.61±0.40 logMAR (p=0.006) at 1 week, 1month, and 3 months. Final BCVA analysis demonstrated that 15 eyes (50%) remained stable and 12 (40%) improved ≥2 lines on BCVA. No ocular toxicity or significant side effects were observed. Conclusions: Intravitreal bevacizumab injection resulted in significant improvement in BCVA as early as 1 week after injection in patients with CSME, and this beneficial effect persisted for up to 3 months. However, the slight reduction in this improvement at 3 months suggests that repeated bevacizumab injections might be necessary. To evaluate the long-term safety and efficacy, further prospective randomized controlled clinical trials will be needed.

الكلمات الدلالية


Article
Vaginal Ph As A Marker For Vaginitis And Menopausal Status
استخدام مؤشر حامضية المهبل كدليل عل التهاب المهبل وحالة سن اليأس

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الخلاصة

ABSTRACT Vaginal PH was determined by universal indicator PH paper in 182 patients seen in Al-Zahara`a Hospital in Najaf city for routine speculum examination. None of the patients were pregnant. Measurements were made of serum levels of follicle – stimulating hormone and estradiol for 81 menopausal patients and vaginal culture were taken for all 182 patients. Vaginal PH was correlated with vaginal cultures and serum follicle – stimulating hormone and estradiol levels by use of statistical analysis. Vaginal PH was elevated in all premenopausal patients with documented bacterial pathogens. Serum estradiol levels showed an inverse and serum follicle – stimulating hormone levels a direct statistical correlation with vaginal PH in postmenopausal patients. Aim of the study: The study had two objectives : (1) to confirm the elevations of vaginal PH in patients with bacterial pathogens in premenopausal women and (2) to examine the relationship of serum FSH and estradiol levels to vaginal PH in postmenopause patients without bacterial pathogens .

الكلمات الدلالية


Article
Amnioinfusion In Labor Induction Of Term Pregnancies With Premature Rupture Rupture Of The Membranes And Low Amniotic Fluid
بزل السائل الأمينوسي الوقائي في حالات الولادة المكتملة التي تعاني من انطلاق الامينوسي مع قلة السائل

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الخلاصة

ABSTRACT Objective: To evaluate the effect of prophylactic amnioinfusion in term pregnancy with (PROM) and low (AF) volume prior to labor induction. Method: 120 women with amnioinfusion and 136 in a control group with term pregnancy and low (AF) were admitted for induction of labor in Basra maternity hospital were studies. Amnioinfusion of normal saline (N/S)37C◦ was realized in the study group of about 500ml/hr through trancervical catheter, while the control group received identical obstetric care except in aminoinfusion. Results: Both studies groups were similar in age, parity, gestional age and interval from rupture membranes until induction while we found that the studied group had less length of labor with decrease risk of (C.S), low maternal complications and less neonatal complications such as apgor score, admittion to (NICU), MAS and neonatal death and the difference was statistically significant. Conclusion: We concluded that prophylactic amnioinfusion improve neonatal outcome and decrease the maternal complications when used in labor induction of term pregnancy with PROM and low AF volume.

الكلمات الدلالية


Article
Pattern Of Infant Feeding
أنماط تغذية الرضع في ذي قار , العراق

المؤلفون: Dr. Tariq Kkudair Hussien د. طارق خضير حسين
الصفحات: 97-103
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الخلاصة

ABSTRACT The aims of this study were to find the prevalence of different patterns of infants feeding in relation to the back ground characteristics of their mothers and to explore the causes of breast feeding failure in Thi-Qar. Across sectional study was conducted in four primary health care centers in Thi- Qar .Total sample of 512 mothers ,whose infants less than two years were included in the study . Data about feeding practices were collected by interviewing the mothers using standard questionnaire designed for the study. The rate of different infants feeding practices were (90.8%) breast feeding, (55.1%)exclusive breast feeding , (35.7%) mixed feeding and (9.1%) bottle feeding among infants less than 6 months old. The rate of breast feeding decreased rapidly among other age groups reaching (72.2%) at age 1-2 years . There was no significant association between patterns of infants feeding and age, parity and educational level of mothers .However, going to work , oral contraceptive use and delivery by caesarean section were significantly associated with bottle feeding . The main reasons for bottle feeding were insufficient breast milk (53.4%) and going back to work (18.2%),and Pediatricians (45.6%) were found to be the main persons prescribing infants formula for mothers. In conclusion, breast feeding was common practice of infants feeding among mothers in Thi-Qar regardless their age, parity and level of education ,while pediatricians , going to work oral contraceptive use and delivery by caesarean section were the main contributors to breast feeding cessation and switch to bottle feeding. Therefore, the health educational programs to promote breast feeding are necessary for both mothers and health care providers ,and the health care providers should also take into consideration the negative impact of caesarean section deliveries and early oral contraceptive use on breast feeding practice.

الكلمات الدلالية


Article
A Study Of Familial Alcoholism
دراسة الإدمان الكحولي العائلي

المؤلفون: Dr.Karim Nasir Hussain د. كريم ناصر حسين
الصفحات: 104-117
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الخلاصة

ABSTRACT Background: Alcoholism hasn’t been a problem just for individuals,but it also has been a problem for families of the affected individuals.In recognizing such a result many studies have been produced to examine the genetic aspect of alcoholism. Objectives: To determine the importance role of genetic in alcoholism and to study the difference between those with positive and negative family history of alcoholism. Methods: A cross sectional study that enrolled( 61) patients who met the diagnosis of alcoholism according to diagnostic criteria of structural clinical interview for diagnosis and statistical of mental disorder text revision (DSM-IV-TR). The patients who attended the psychiatric unit in Al-Diwaniya Teaching Hospital for the period 1st July, 2008 – 1st June 2010. Results: This study revealed that (61) alcoholics admitted to hospital for treatment met the diagnosis of alcoholism according to the (DSM-IV-TR) were evaluated. The study revealed that 90% of the patients with positive family history of alcoholism reported antisocial behaviour, while those without family history reported only 16.13% antisocial behaviour. Patients with family history of alcoholism showed more family problems and the reverse regarding psychiatric disorders. Conclusions: This study proveds that the association of psychiatric disorders as depression, severe anxiety and social phobia may occur with those without family history of alcoholism. We also noticed that patients with positive family history of alcoholism are of younger age of onset, with more symptoms of alcoholic dependence, tended to drink more, run more severe course and reported more antisocial behaviour.

الكلمات الدلالية


Article
Bacteriology And Antibacterial Susceptibility Of Tonsillopharyngitis And Chronic Suppurative Otitis Media Cross Sectional Study In Al.Habobi Hospital-Thi-Qar
دراسة مقطعية حول البكتريا المسببة لالتهاب اللوزتين و البلعوم والتهاب الاذن الوسطى المزمن في مستشفى الحبوبي-ذي قار

المؤلفون: Dr.mushtaq N.almalki د. مشتاق نعمة
الصفحات: 118-125
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الخلاصة

ABSTRACT: Antibacterial resistance is a great problem on proper management of tonsillopharyngitis and chronic otitis media.To determine the antibacterial susceptibility of the common causative bacteria throat and ear swabs were sent for culture and antibiotic sensitivity testing from out patients attending AL.Habobi hospital over aperiod from September 2009 to September 2010. Of 102 patients with tonsillopharyngitis , Beta haemolytic streptococcus type A ,was the commonest cause accounting for 59.8% of all isolated bacteria, followed by 29.4% was staphylococcus.On other hand pseudomonas represent the top of the list of bacterial causes of chronic suppurative otitis media(46%) ,followed by staphylococcus aureus (27.6%). Amikacin has the greater chance of action among most isolated bacteria in this study.Sensitivity to commonly used antibacterial agent like amoxicillin, cephalosporin, pencillin, erythromycin and co-trimazole were less.


Article
In Vitro Assessment Of Antifungal Potential Of Apple Cider Vinegar And Acetic Acid Versus Fluconazole In Clinical Isolates Of Otomycosis
التقييم المختبري لقابلية خل التفاح و حامض الخليك المضادة للفطريات مقارنة بالفلوكونازول في عزلات سريرية لفطريات الاذن.

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الخلاصة

ABSTRACT Background: There has been an increase in the prevalence of otomycosis in recent years. This has been linked to the extensive use of antibiotics, use of immunosuppressant drugs and steroids for a variety of malignant and immunological diseases. Treatment of otomycosis is challenging, and requires a close follow-up; in addition treatment with topical or systemic antifungal drugs might be associated with problems of resistance, mucosal irritation, and systemic toxicities. Candida albicans and Aspergillus niger are the most commonly identified organisms. Aim: the aim of this study is to investigate the antifungal potential of apple cider vinegar and acetic acid in a hope to find a safer alternative to traditional antifungal drugs in treatment of otomycosis. Patients and methods: ear swaps were collected from 18 patients attending otolaryngology outpatient clinic-Al-Habboobi Hospital who presented with aural symptoms suggestive of otomycosis.fungal identification was done depending on microscopical and colonial morphology. Antifungal effect of the tested agents was assessed by agar well-diffusion assay. Results: 18 samples were examined, 13 (72%) of them were positive for fungal growth, 6 were Aspergillus niger , 1 was Aspergillus flavus, 2 were Candida albicans, and the other 4 were Non- Candida albicans. Apple cider vinegar(5%) inhibits growth of Aspergillus niger, Aspergillus flavus, Candida albicans and Non- Candida albicans with average diameter of inhibition zones of 15mm, 13mm, 17.5mm, 17 mm respectively, while the average diameters noted with acetic acid 2% were 10.5mm, 11mm, 13mm, 13.5mm respectively. Fluconazole (5mg/ml) inhibits growth of the Aspergillus niger, Aspergillus flavus with average diameters of 14mm,20mm respectively,while cause no inhibition of Candida albicans and Non- Candida albicans. Conclusion: Apple cider vinegar and acetic acid have significant antifungal activity at the tested concentrations against Aspergillus niger, Aspergillus flavus, and fluconazole resistant Candida albicans and Non- Candida albicans.


Article
Oral Pyogenic Granuloma In Thi Qar Governorate :Retrospective Study
أنتشار العقد الحبيبية الخمجية الفموية في محافظة ذي قار دراسة رجعية

المؤلفون: Dr. Nabra F. Salih د. نبرى فنر صالح
الصفحات: 134-138
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الخلاصة

ABSTRACT : Oral pyogenic granuloma is the most common inflammatory hyperplasia seen in the oral cavity the purpose of this study was to retrospectively analyze the clincopathologic feature , histologic pattern and relation to pregnancy in Al-Nasyriah governorate . A total of 100 cases of pyogenic granuloma (PG) during an 10 years period from 2000-2010 were examined. the data were reviewed and analyzed for age , gender , site , clinical and histopathologic features. The results shows that the age mean of occurrence was 29 years and the greatest degree of occurrence in third decade of life in young adult females. The gingiva was the most common affected site ( 38%) and the maxilla more affected than mandibule ( 24%) , the main complain was bleeding ( 65%) , the higher percent in females group was in pregnant women (66%). Non lobular capillary hemangioma (NLCH) (PG) were more fequentluy (73%) than lobular capillary hemangioma ( LCH) (PG) (27%). Because of the high frequency of PG in the oral cavity especially during pregnancy so need for proper diagnosis and treatment .

الكلمات الدلالية


Article
Detection Of Hemoglobinopathies In Hypochromic, Microcytic And Sickeled Cell Blood Films By Hemoglobin Electrophoresis
كشف اعتلالات الهيموغلوبين في الاشخاص حاملي كريات الدم الحمرالمنجلية والصغيرة الشاحبة بواسطة الترحيل الكهربائي للهيموغلوبين

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الخلاصة

ABSTRACT background: The hemoglobin molecule (Hb) is protein carries a negative charge that render it attracts to anode pole causing separate it and moving toward the positive pole of electric current, affected by the movement of this type of charge (negative or positive) and strength as well as the molecular weight of hemoglobin type. Until these days, there are more than 300 known genetic mutation may occur in hemoglobin molecule. Some of them with clear clinical implications that threat health, especially for heterozygous states. Objective: To detect some of hemoglobinopathies such as β- thalassemia and sickle cell anemia cases by hemoglobin electrophoresis technique in population sample identified from Nassiriyah governorate in Iraq. Methods: Eighty samples of blood were drawn from subjects who suspected to have hemoglobinopathies and examined by Hb electrophoresis technique in College of medicine – Thiqar University. The diagnosis of hemoglobinopathies was made on the basis of hemoglobin electrophoresis, sickling tests, and family studies. Persons, who have low level of hemoglobin concentrations, accompanied with elevation of abnormal hemoglobin percentage, were involved in this study. Fifty eight cases of hemoglobinopathies were diagnosed, 30 of 80 (37.5%) as β- thalassemia, and 28 of 80(35%) as sickle cell disease carriers. Results: Iraqi β-thalassemia and sickle cell anemia carriers were identified in hematology sections in Nasseriah governorate hospitals. Recent hemoglobin protein study revealed the presence of different common defected hemoglobin types associated with these disorders, distributed as the following: 15 subjects (18.7 %) were (HbAS) and 8 (10%) were (HbFS( sickle cell minor carriers, 7(8.8%) were (HbS) sickle cell disease, while thalassemic major were: 9 (11.3%) with (HbF) , and 12 (15%) with (HbAF) type. Thalassemia minor hemoglobin (HbA2) type represents 7 (8.8%). However, there are also 22 subjects were have normal Hb electrophoresis. Conclusion: The investigations described below manifested a rapid and simple method which allows quantitative analysis of the proportions of the various hemoglobins forms present. Hemoglobin gel electrophoresis is a simple and convenient technique for the study of the hereditary hemoglobimiopathies in alkaline pH (4.8 to 6.8). We suggest extending its usage to the detection of other hemoglobin disorders.

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Article
Isolation And Serotyping Of Salmonella Species In Diarrheal Children
عزل وتصنيف بكتريا السالمونيلاSalmonella من الاطفال المصابين بالأسهال

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الخلاصة

SUMMARY This study was carried out to isolate Salmonella species from children, 170 fecal samples were collected from children aged (5-12) years of both sexes that had suffering from diarrhea in Teaching laboratories of Al- Hussein Hospital in Thi-Qar governorate. Nineteen isolates were diagnosed as genus Salmonella and ensured by National center of Salmonella in Baghdad, five Salmonella serotypes were determined as (Salmonella typhimurium (8) (42.1%), S.braenderup (6) (31.58%), S.hadar (3) (15.78%), S.eneritidis (1) (5.27%), and S. munchen (1) (5.27%). The results revealed that the rate of Salmonella isolates in fecal samples of children was (11.17%). According to gender of children the rate of Salmonella isolates was (68.42%) in males and (31.58%) in females. In respect to the rate of Salmonella isolation in different age of children; age (5-8) years showed the highest rate respectively. This article is a part of master thesis

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