Table of content

Diyala Journal of Medicine

مجلة ديالى الطبية

ISSN: 97642219
Publisher: Diyala University
Faculty: Medicine
Language: English

This journal is Open Access

About

A scientific, medical journal published by medical college , diyala university at 2010
No. of issues per year(2)
No. of papers per issue(15-20)
No. of issue published (3) issue

Loading...
Contact info

djm.diyala@yahoo.com

Table of content: 2015 volume:8 issue:1

Article
Cardiovascular Autonomic Impairment in Parkinson Disease

Loading...
Loading...
Abstract

Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor dysfunction and several non-motor features. Dysautonomia is a significant non-motor feature as well as a neuropsychiatric symptom. Objective: To assess cardiovascular autonomic function in Parkinson patients. Patients and Methods: Samples were collected from Al Kadhimiya teaching hospital and Baquba teaching hospital in a period lasts from 1st January to 1st November 2013. Cardiovascular autonomic function had been tested in 44 Parkinson patients with autonomic dysfunction, 23 Parkinson patients without autonomic dysfunction and 25 healthy matched controls; using Valsalva maneuver, 30:15 ratio, and effect of posture on blood pressure. Results: The most frequent dysautonomic symptoms in parkinson disease were fainting and dizziness (postural hypotension) with a frequency of 26.8% with a P-value 0.015. The comparison between valsalva levels in three groups of study population was significant (P- value 0.04). The comparison between 30:15 ratio in three groups of study population was not significant statistically (P-value 0.344). Conclusion: Cardiovascular autonomic dysfunction is a common non-motor symptom associated with Parkinson's disease. It may precede the development of the cardinal motor symptoms in PD, making cardiovascular dysfunction an attractive target for early detection and potential neuroprotective strategies for PD. Valsalva maneuver and effect of changes in posture on blood pressure are affecting tests in cardiovascular autonomic study.


Article
Molluscum Contagiosum in Baquba City Epidimiological Study with Identification of Mc Viruses by Polymeras Chain Reaction

Loading...
Loading...
Abstract

Background: Molluscum contagiosum is a DNA virus, which may infect the mucous membrane, it is caused by Molluscipox virus and there are four types (MCV1-4). The sites of predilection of lesions are the face and neck, both genders equally affected and most commonly seen in childhood age group. Objectives: To study the epidemiological variables of Molluscum contagiosum and to confirm the clinical diagnosis and type of Molluscum cotagiosum virus (MCV) by Polymerase chain reaction (PCR) technique. Patients and methods: The present study was conducted for the period from 1st November 2011 to 30th April 2012 in outpatient clinic of Baquba teaching hospital in Baquba city. One hundred and sixty two patients with molluscum contagiosum were examined and diagnosed clinically and the diagnosis was confirmed by Polymerase chain reaction technique .The lesions of moluscum contagiosum were seen on different sites of the body, age of patients ranged from (1-80 years) with a mean age of 35+_9years . They were 114(70.6%) males and 48(29.4%) females. Results: The results showed that 72 (44.4%) patients of age group (31-40 years), of which 50 (70%) were males and 22 (30%) females, 35 (21.6%) of age group (ten years or less). This study revealed that 56(35%) of patients were illiterate, without statistical significant difference between MC infection and educational levels. In 78% of patients the lesions located on the head and neck, 70% on the right side and in 78% of patients the number of lesions was ≤10 lesions, 70% of patients lived in the urban areas and 30% in rural areas. Eighty five percent (85%) of patients give positive results for MCV, 58.8% of them shows positive results for MCV type 1 and 2 (73.3% MCV-2 and 26.7% MCV-1), while 41.2% shows negative results . Conclusion: We concluded that Molluscum contagiosum was a disease of adult, predominantly males and on the right side of the face and 73.3% of PCR positive results were MCV-2.


Article
The Effect of Bleaching Agents on the Shear Bond Strength of Recently Bonded Restorations to Enamel

Authors: Manal Hussain Abd-Alla
Pages: 14-20
Loading...
Loading...
Abstract

Background: Fuji II LC, one type of resin-modified glass ionomer cements, has an excellent bonding efficacy to both enamel and dentin. This material is considered the material of choice for treatment of cervical lesions located along the cementoenamel junction. Objectives: To evaluate the effect of post-operative bleaching on the shear bond strength of resin-modified glass ionomer cement to enamel. Methods: Enamel specimens of human molars were bonded with resin-modified glass ionomer (Fuji II LC) and divided into six groups: three control and three bleaching groups. Two bleaching groups were bleached with a 38% hydrogen peroxide either within one hour (B1) or after one week of bonding (B2). The third group (B3) was exposed to a 10% carbamide peroxide bleaching agent for two weeks. Shear bond strength was tested with a universal-testing machine and the data were analyzed by ANOVA test. Results: A significant difference in Shear bond strength was found between the groups (p=0.032). Tukey’s test revealed a significant reduction in the shear bonding strength of B3 compared with the control group (p< 0.05). Conclusions: Post-operative bleaching with 38% hydrogen peroxide did not compromise bonding efficacy to enamel. However, bleaching with 10% carbamide peroxide reduced bonding strength of resin-modified glass ionomer to enamel significantly.


Article
Is Grand Multiparity Still An Obstetrics Risk?

Loading...
Loading...
Abstract

Background: Grand multiparity has been known to be an obstetric risk because of the documented complications associated with the condition, and it is an indication for booking in a tertiary health institution. Patients and Methods: Cross – sectional study was conducted in Al-Batool teaching hospital during the period from July 2014 to November 2014. Total number of deliveries was 200. Samples (100 grand multipara women and 100 woman as control group), who were admitted to the maternity unit for labour and delivery, the two groups were matched for age, antepartum outcome, intrapartum outcome, postpartum outcome and fetal outcome to compare the risk between grand multiparity and control. Results: Two hundred of grand multiparous woman and control group were included in the present study the mean age was (32.32 ± 6.006) years. There was (56%) of grand multiaparity have anemia and other medical diseases such as hypertension, diabetes mellitus, epilepsy and urinary tract infection. Statistically significant differences noticed when compared with the control group (p- value ≤ 0.05). Also there were higher incidence of preterm labour and abruption placenta in grand multiparity comparing to control group. However higher incidence of caesarian section delivery in grand multiparous woman than control group (60%, 40%) respectively. The most common cause for caesarian section was due to previous scar, which was (58.8%) in control versus (51.6%) in grand multiparity. Regarding the perinatal outcome there was Apgar score ≤ 7 at 1 minute (61%, 28%) in grand multiparity and control respectively which was statistically significant. Conclusion: The grand multiparity still be considered a high risk in pregnancy due to medical and obstetrical complications, also it is necessary to provide a good health care for grand multiparous woman, and their neonates.


Article
Identification and Differentiation of Mycobacterium Avium Subspecies Paratuberculosis Isolates Using and pAM-3 as a DNA Probe

Loading...
Loading...
Abstract

Background: Mycobacteriu avium subsp.paratuberculosis (MAP) is the causative agent of Johne’s disease. It is a very slow growing bacterium on synthetic medium. The use of conventional methods for diagnosis is time consuming and not accurate. Objectives: The use of molecular biological techniques for fast and accurate diagnosis of Mycobacterium avium subsp.paratuberculosis isolates. Materials and methods: DNA was extracted and prepared from four Mycobacterium avium subsp.paratuberculosis and four Mycobacterium tuberculosis bovis isolates. The extracted DNA was subjected to PCR by using specific primers and the isolates were distinguished and differentiated by hybridization technique using pAM-3 specific probe developed in New Zealand. Results: The PCR products gave the requested DNA fragment of 163 base pairs. The probe reacted specifically with targeted DNA fragment of paratubreculosis bacterial isolates but not with tuberculosis bovis isolates. Conclusion: The use of PCR and specific DNA probe for the diagnosis of MAP is a fast and accurate method for diagnosis of MAP.


Article
Antibiotic Abuse in the Surgical Word in Baquba Teaching Hospital

Loading...
Loading...
Abstract

Background: The common use of antibiotics has led to at least two adverse consequences. One consequence includes unpleasant and occasionally lethal side effects resulting from changes in the normal microbial flora, these events leading to many problems sometimes require surgical removal or in some cases, lead to death. Objective: To investigate the usage and pattern of antibiotics in the surgical ward of Baquba teaching hospital. Patients and Methods: This is a retrospective study perform in Baquba teaching hospital during the period 2011-2013. The data collected from files of the patients who underwent different surgeries from the statistic unit in the hospital, recalled for which patient received the antibiotics and for how long. The types of surgeries involved in the study are those which belong to class one and two. Also prescribing advanced antibiotics instead of starting with the simple one is considered abuse. Results: Seven hundreds and ninety five case file of patients underwent clean and clean-contaminated surgeries in Baquba teaching hospital was reviewed for the use of antibiotics preoperatively and/or postoperatively, the type of antibiotic used and the duration, 541 (68%) patients were underwent clean surgeries. All of them received antibiotics postoperatively, 254 (32%) patients were underwent clean contaminated surgeries. None of them received prophylactic antibiotics and all of them received postoperative antibiotics in the form of parenteral antibiotics for 7-10 days (till removal of the stiches) and continue on enteral antibiotics for another 3-5 days following removal of the stiches.367 (67.8%) patients of those underwent clean surgeries prescribed third generation cephalosporene (Cefotaxime). 233 (91.7) patients of those underwent clean contaminated surgeries given a combination of antibiotics (Cefotaxime+Metronidazole+/- Gentamycin).Antibiotics were abused in 600 (75.47%) patients. Only 195 (24.52%) patients prescribed antibiotics in the scientific way. Conclusion: The random prescription of antibacterial is high leading to abuse of antibiotics. The number of antibacterials used and the duration shown to be increased. The combination of some antibiotics needs further evaluation.


Article
Possible Role of Biological Agent on Characteristics of Sperm in Patients with Spondiloarthritis

Authors: Atta AH. Mousa
Pages: 44-48
Loading...
Loading...
Abstract

Background: The role of TNF-α and TNF-α antagonists on seminal fluid parameters in men is controversial. TNF-α is a cytokine had a wide range of cellular effects. In testis, “TNF-α is produced by germ cells and it has a role in the regulation of spermatogenesis”. Objective: to study the effect of biological agent on sperm quality in a group of spondyloarthritis patients Patients and Methods: A prospective study was carried out in Baghdad teaching hospital during the period starting on 1st of January 2013 till the end of October 2013 .All semen samples of (60) spondyloarthritis patients and controls (60) was collected by masturbation after (72) hour of sexual abstinence. The semen samples was examined with regard to sperm concentration, motility, and morphology, according to WHO 1999 guidelines.. Results were compared with controls Results: According semen parameters such as Volume, PH, Count, Motility Morphology in two groups of spondyloarthritis there were no significant differences noticed between TNF blocking agents and semen parameters when compared to controls group on( baseline ) but after (40 weeks), Regarding motility and morphology significant differences (P<0.001) were found between cases and healthy controls. Conclusion: Biological agents (infliximab&enbrel) had no affect on seminal fluid parameters such as volume, PH and sperm concentration, but it decreased motility of sperm and percent of normal morphology

Keywords

Sperm --- Biological agent --- Semen --- arthritis --- TNF


Article
Occupational Irritant Hand Dermatitis among Nurses in Al-batool Teaching Hospital

Authors:
Pages: 49-53
Loading...
Loading...
Abstract

Background: Occupational irritant hand dermatitis (IHD) is frequent in hospital workers, especially in nurses. A comprehensive understanding regarding hand dermatitis is essential for establishing proper prevention and treatment strategies. Aims: The purpose of this study is to identify the prevalence of occupational irritant contact hand dermatitis in hospital nursing staffs and to identify the risk factors for hand dermatitis among nurses in Al-batool teaching hospital. . Patient and Methods: A Cross sectional study was conducted in Al-batool teaching hospital in Baquba city from 1st October 2013 to 30th March 2014. Completed questionnaires were obtained from 120 nurses (male and female) by face to face interview. In questionnaires we ask about the occurrence of the occupational hand dermatitis as diagnosed by dermatologist and the relation between hand dermatitis and the use of latex gloves and cleansing agent and the risk factor associated with this dermatitis. Results: Irritant hand dermatitis was diagnosed in 57 nurses. The prevalence of occupational irritant hand dermatitis was 48% (57 of the 120 nurses). We found hand dermatitis prevalence is of 54% (31 of 57) in Gynecological department nurses whereas the prevalence in pediatric department nurses was 46% (26 of 57). 60% (34 of the 57) of the cases presented with a hand dermatitis, the cause was latex gloves and in 25% (14 of 57) of nurses the cause was cleansing products, and the remaining 15% (9 of the 57) the cause was combined of both. 23% of nurses report a history of asthma (13 of the 57) and 33 %( 19 of 57) of nurses have allergic rhinitis. Also there was a family history of atopy in 44 % of nurses (25 of 57). There is increase in the occupational irritant contact hand dermatitis with increase period of work, 30% in nurse work more than 10 years. Conclusions: Our study indicates that it is necessary to provide nurse with specific skin care advice as part of their training. This might help to identify trainees at increased risk of developing occupational irritant contact hand dermatitis, encouraging the initiation of appropriate skin protection measures.


Article
Prevalence of Anemia among Pregnant Women Attending Primary Health Care Center in Bab-Al-Moudham

Loading...
Loading...
Abstract

Background: Anemia is define as decreased hemoglobin level, or circulating red blood cells and it is the most common hematological disorder during pregnancy. Objective(s): To identify prevalence of anemia, risk factors that contribute to the occurrence of anemia, and to explain the main types of anemia during pregnancy. Materials and methods: A descriptive cross- sectional study conducted at primary health care in Bab- Al-Moudham center in Baghdad city, the sample was selected by non- probability (convenient sampling) and sample size (150). The study started from 1nd March to 10th June 2012, the data was collected by direct interview technique. Previous questionnaire was structured by the researchers to measure the variable of the study; these information infants include (age, educational level, number of children, type of delivery, and type of feeding, .etc). Results: The results shows that most frequent age group was (2-29) years, (34.7%) of mothers were primary school graduate and about (54%) of the pregnant women with anemia had no abortion and no bleeding. Conclusions: The study concluded that higher percentage of pregnant mothers was low rate hemoglobin. Recommendations: The study recommended that encourage pregnant mothers to visit primary health care centers early and regularly and take drugs that prevent the occurrence of anemia during pregnancy period.


Article
Maternal Factors that Determining Birth Spacing Interval among a Sample of the Women at Child Bearing Age

Authors: Aqeel Abbas Noaman
Pages: 60-65
Loading...
Loading...
Abstract

Background: Birth interval is the length of time between two successive live births. It might be affected with socio-economic factors related to mother as age, education and parity. Objectives: To determine the rate of birth spacing interval for a sample of women at the child bearing age and to find out any association between maternal factors and birth spacing interval. Subjects and methods: A cross-sectional study was conducted in Al- Takia PHC center by using special questionnaire from 15th September 2012 to 15th September 2013. Sample size was 184 women at child bearing age. Results: Out of 184 women at the child bearing age (60.33%) had birth interval less than two years, (68.5%) below 25 years had birth interval shorter than two years, (60%) and (32.9%) of women with birth spacing interval < 2 years and ≥ 2 years respectively were primary school graduates, (83.8%) and (74%) of the studied women with birth spacing interval < 2 years and ≥ 2 years respectively were housewives, (45.9%) of women with birth interval < 2 years had high parity ( ≥ 5 live births). Conclusions: All studied maternal factors were significantly associated with length of birth interval except mother's work status.


Article
Microbial Contamination Associated with Computer Keyboards and Mouse Devices in Diyala University

Loading...
Loading...
Abstract

Background: Surface contamination of public user interface systems such as computer keyboards and mouse devices may play a role in community-acquired outbreaks by acting as an environmental vehicle in transmission of potential hazardous microorganisms. There is no economical way to test all keyboards and mice out there, but there is a common-sense way to prevent bacterial contamination or eliminate it if it exists. Objectives: To explore the bacterial contamination rates in multi-user and single-user computer accessories (keyboards and mouse devices) in certain colleges of the Diyala University. Materials and methods: This study was conducted in Bacteriology laboratory- Colleges of Veterinary Medicine- Diyala University for the period from October 2012 to April 2013. A total of 155 swabs were collected aseptically from 60 computers in 4 colleges, namely, College of Medicine, Veterinary Medicine, Science, and Education- Pure Science. Swabs were streaked on blood and MacConkey's agar plates then incubated for 24 hours at 37 ̊ C. Final identification of bacterial species was based on standard bacteriological and biochemical criteria. Results: The results showed that the overall contamination rate in the four colleges was (54.8%). The highest isolation rate of bacterial contaminant was Staphylococcus epidermidis (30.6%), followed by Escherichia coli (29.4%). Fungi constitute (17.6 %) of isolates. The College of Veterinary Medicine rank at the top with significant highest contamination rate (52.7%), followed by the College of Medicine with a contamination rate (21.2). Computers of the internet centers harbor the significant highest contamination rate compared to administrative units (71.8% and 28.2%) respectively. The contamination rate was higher in mouse devices compared to keyboards (57.6% vs 42.3%). Conclusion: The study concluded that continuous education of students and employees about the risk of bacterial contamination arise from using the computers, beside the periodic disinfection of computer accessories may aid the fight against transmission and spreading of infectious pathogens.


Article
Assessment of Treatment Response of Iraqi Patients with Membranoproliferative Glomerulonephritis with Emphasis on Renal Function and Proteinuria Regression

Authors: Faiz Rashid Abayechi
Pages: 73-85
Loading...
Loading...
Abstract

Background: Membranoproliferative glomerulonephritis (MPGN) is a pattern of glomerular injury with characteristic light microscopic changes. It can be primary idiopathic renal disease or secondary to chronic infections, autoimmune diseases and complements dysregulation. Objective: To evaluate treatment response in a group of patients with MPGN regarding renal function and proteinuria regression. Patient and Methods: Thirty three adult patients with MPGN (above the age of 18 years) were included in the study. Males were 19 and females were 14. All patients were followed up for two years. Laboratory investigations included complete blood counts, urine examination, renal function test, lipid profile, virology screen (hepatitis B virus and hepatitis C virus), collagen diseases screen (antinuclear Ab, anti double stranded DNA, extractable nuclear antigens, complements C3 and C4), also screening for multiple myeloma was done with serum protein electrophoresis and urine bence jones protein. All patients were given standard form of treatment (Anti platelets, statins, diuretics, angiotensin converting enzyme inhibitors/angiotensin receptor blockers), some patients were given steroids, others, immunosuppressive drugs.Their responses to treatment were studied and compared. Results: The cause of MPGN in this study was idiopathic in twenty six patients (79%). It was secondary to HBV, HCV, and systemic lupus erythematosus in seven patients (21%). Four (58%) out of seven patients with normal RFT have partial response to steroid therapy and they showed decreased proteinuria. The remaining three (42%) patients showed no response. Two Patients with normal RFT who received mycophenolate mofetil, responds by decreasing their proteinuria to less than 1 g / 24h. nine patients with impaired RFT received steroid treatment only or steroid plus MMF, four (44%) patients have stabilized renal function, the remaining five (56%) patients had progressive decline in renal function. Three patients with HBV infection who were given alfa interferon or lamivudine showed stabilized RFT and decreased proteinuria. One patient with HCV infection showed progressive decline in renal function, he was maintained on standard treatment only. Two patients with SLE and impaired RFT were given cyclophosphamide and steroid, their RFT stabilized during the follow up period Conclusion: Patients who presents with normal RFT have better response to treatment. Than patients who presents with impaired RFT. Also patients with secondary MPGN (HBV and SLE) have responded at least partially to antiviral and /or immunosuppressive therapy.

Table of content: volume:8 issue:1