Table of content

Muthanna Medical Journal

مجلة المثنى الطبية

ISSN: 2226146x
Publisher: Al-Muthanna University
Faculty:
Language: English

This journal is Open Access

About

Muthanna Medical Journal (MMJ) is the official journal of Muthanna Medical College, a semiannual peer-reviewed online and print journal. The MMJ allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional/subject-based repository.
The Journal follows the ICMJE's Recommendations for the Conduct, Reporting, Editing and Publication of Scholarly Work in Medical Journals.

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Contact info

Postal Mail
Muthanna Medical School
Samawah
Tel: 0782542-5669
Email: yousif_ghaly@yahoo.com

Table of content: 2015 volume:2 issue:1

Article
The physiological evaluations of C-reactive protein, anti-cyclic citrullinated peptide antibody and RF in the rheumatoid arthritis patients of Al-Nassyria hospital

Authors: Talib F. Abbas
Pages: 1-4
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Abstract

The assessment of autoantibody before clinical onset of Rheumatoid Arthritis, has been helped in establishing early diagnosis. Recent studies on RA described many inflammatory conditions that precede joints inflammations. Anti-CCP and IgM-RF were evaluated in 10-RA patients and in same number as control. Anti-CCP was detected by ELISA and IgM-RF using latex agglutination test, while the CRP was measured by latex turbi-imetric immunoassay, and the ESR was measured by Westergren method. The values of Anti-CCP antibody is more sensitive than the other tests, in 50% were positive, and 50% negative. CRP measures were fluctuated around 37% positive and 63% were negative. ESR values have been shown a significant increase in 90% positive, whereas 10% negative. RF show a significant increase by 60% positivity. The positive value was higher for anti-CCP antibodies in comparison to other markers for RA patients. Interestingly, there were not significant relation between anti-CCP antibody titers and inflammatory markers such as ESR and CRP. However, there is a tighten relation between Anti-CCP and RF had been confirmed.


Article
Bone marrow biopsy in uremic patients with erythropoietin therapy January 2009 – July 2012

Authors: Hassan Abdul Amir AL-Daghir
Pages: 5-9
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Abstract

The aimed of this study is identified the BM changes that associated with (CRF), especially in those patients, treated with the recombinant erythropoietin and secondly how was the hematological response to erythropoietin itself. We followed 75 uremic patients whom were on (RDP) and were treated with a recombinant erythropoietin and supplemented by a parenteral iron because of symptomatic anemia, by bone marrow biopsy through anterior superior an iliac crest approach. All the specimens had been submitted to a histopathological examination by the same well certified pathologist. We found that 50 patients (66.66%) were males and 25 patients (33.33%) were females. Regarding the BM biopsy results 35 patients (46.66%) got (EH) 30 patients (40%) got normal cellular BM 10 patients (13.33%) got hypoplastic BM. There was no evidence of granuloma, carcinoma, sclerosis osteomalacia or osteoporosis in any of our patients. Regarding the response to erythropoietin, we found that most of our patients got a frequently symptomatic anemia and needed a blood transfusion irrespective of the regular (HD) that was supplemented by erythropoietin with a parenteral iron. We concluded that there was no specific BM changes that can be attributed to CRF. As far as the matter of erythrpoietin therapy was concerned, we found that most of our patients were still in a real need for a blood transfusion because of the symptomatic anemia irrespective of the erythropoietin administration in addition to parenteral iron. So we think that we must search for other modalities of therapy for the anemia in CRF in addition or an alternative to erythropoietin which had not reduced remarkably the need for the blood transfusion in our patients.

Keywords


Article
MRI finding versus arthroscopic finding regarding ACL injury

Pages: 10-14
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Abstract

Abstract 25 patients, 20 male patients and 5 female patients with knee joint injury, all of them with single knee joint injury. 25 knee joints are examined during this study, all patients are perform MRI in different centers send with report of the MRI from expert radiologist. They perform arthroscopy in Al Sadder medical city from January 2013 – October 2014. The aim of this study is to confirmed or unconfirmed ACL injury after clinical examination and MRI which they perform to them either in our center or other centers. The majority of ACL injuries 70% occur while playing agility sports, and the most often reported sports are football. About 70% of ACL injuries are sustained through noncontact mechanisms, while the remaining 30% result from direct contact. The aim of this study is to assess the diagnostic value and compare the accuracy (sensitivity and specificity) of MRI to arthroscopic finding regarding the ACL injury.

Keywords

MRI --- ACL injury --- Radiologist


Article
Mouse monoclonal antibodies and immunohistochemical technique for determination of sex steroid receptors and human epidermal growth factor receptor in breast cancer

Pages: 15-22
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Abstract

Breast cancer is one of the most common malignancies in women. The current study was conducted with the objective of assessing estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (Her2/neu) reactivity patterns of breast cancers and to evaluate their association with clinicopathological features. Immunohistochemical (IHC) procedure was used to detect the expression of ER, PR and HER2/neu in postoperative paraffin blocks of breast tumors and statistically analyzed their correlations with clinicopathological characteristics. Most of the patients (66.0%) were ≤50 years at diagnosis. The left breast was more commonly involved (57%), tumor size ranged from 0.5 - 13.0 cm. The staining of Her2/neu was mainly localized in the membrane, whereas ER, PR, were localized in the nucleus. ER positivity was observed in 70% grade I, 48.2% grade II and 3.5% grade III carcinomas (P<0.05). Similarly PR positivity was observed in 70% grade I, 36.14% grade II and 1.75% grade III carcinomas (P<0.05). HER2/neu was positive in 1 (10%) case of grade I carcinoma, 31 (37.35%) cases of the grade II carcinoma and 24 (42.11%) cases of grade III carcinoma. In the HER-2/neu positive tumors, ER and PR expression in high grade tumors was significantly decreased compared with intermediate grade tumors (ER 5.6% vs 10.5; PR 0% vs 5.3%). Among the ER, PR and HER2/neu statuses, a significant correlation was observed between ER expression and PR status (P<0.05), whereas the expression of ER and PR exhibited a negative correlation with HER2 status (P<0.05). We also demonstrated a significant correlation between the HER2/neu subtypes with poor histological grade (P<0.05). In conclusion, there is a definite correlation between IHC indices and clinicopathological characteristics in breast carcinomas.


Article
Ocular complications following intravitreal Bevacizumab (Ava

Authors: Saif Abass AL-Shamarti
Pages: 23-26
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Abstract

To assess the rate of ocular complications in patients following intravitre albevacizumab (Avastine) injection for patients with proliferative Diabetic Retinopathy. The study was conducted IBSAR center in Al-NAJAF, IRAQ on 2014, 100 patients participated in the study, their age ranging from 50 years old to 63 years old and followed up for 6 months for observation of the complications. The results were; ten patients have subconjunctival hemorrhage, two patients have post-operative endophthalmitis, three patients have slightly increase in their IOP post operatively, five patients complain of post-operative ocular pain, Sterile uveitis occurs in 1 patient, No retinal detachment occurs, No vitreous hemorrhage occurs. Intravitreal (Avastin) injectionis generally safe with minimal risks, if we take good attention regarding sterilization, technique & surgical procedure.


Article
Tensile strength of repaired acrylic resin influenced by water aging

Authors: Firas Abd Kati Al-Shammari
Pages: 27-33
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Abstract

Acrylic resins are commonly used for fabrication of removable dentures. The aim of this study was to assess the effect of aging in water on tensile strength of acrylic after manipulation with chemical and mechanical surface treatments. 160 specimens were prepared from heat-cured resins and divided into 4 groups according to time of immersion in water. Acrylic samples were cut into two halves and then repaired with heat-cured acrylic resin. All acrylic samples were tested under tensile loads till fracture. The tensile strength was affected by water aging and surface treatments used. The acrylic samples reinforced by metal wire had the maximum tensile strength for all groups. In addition, the acetone group created a higher tensile strength than monomer and untreated group (P<0.001). Furthermore, the application of a liquid monomer increased significantly the tensile strength as compared to untreated group (P<0.001). Moreover, There were a highly significant differences between repaired groups (P<0.001). For water aging, there were a highly significant differences among all groups (P<0.001). The tensile strength of repaired samples which immersed in water for one day was greater than that of samples immersed for 7 days, two and 4 weeks. The present study concluded that the tensile strength of acrylic resin had been significantly affected by water aging and surface treatments used. The tensile strength of repaired acrylic resin had been significantly reduced when samples immersed in water for long time. It is recommended for the patients to repair their fractured dentures immediately.


Article
Assessment of risk factors in pregnant women in Al-Samawa city

Pages: 34-38
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Abstract

Aiming to assess the risk factors in pregnant women in Al-Samawah city, and to find out the relationship between these risk factors with certain variables factors. A cross sectional study was carried out during 1st of December 2013 through April 2014 including pregnant women attending the primary health care centers in Al- Samawah city. Data were collected through direct interview of pregnant women and from surveying their medical records using especial designed questionnaire form. A significant association has been detected between age groups of pregnant women and bleeding during pregnancy (P= 0.01). Old age pregnancy (more than 35 years) had the higher percentage of risk factors, and the degree of relatives between women and their husbands is (35.9%). Old age pregnancy had a higher percentage of anemia, hypertension and bleeding during pregnancy. The BMI higher percentage (49.5) of pregnant women were in the normal score, it was close to the international standards. The BMI is significantly association with D.M (p= 0.038). The Socio-Economic-Status (SES) of the most families in this sample were at low level (65). Further, a statistically significant association has been detected between (SES) of pregnant women and D.M (P = 0. 012). More than half (58) of women had in adequate visit to (PHCs), sixth of the deliveries was at home, one third of pregnant women had risk factors of them one quarter had more than risk.


Article
Objective assessment tool of pharmacist skills

Pages: 39-45
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Abstract

The objective of this study is to assess the pharmacist skills and focus on the certain important defects in pharmacist work up and possible causes for these defects and suitable resolution ways. A cross sectional study was involved fourteen pharmacists in two government hospitals in al-Muthana, Iraq. Ten pharmacist in hospital A and Four in hospital B and include collection of data over one week of April 2015. In this study we concentrate on following vital activities (VA.s) with high importance in production of sufficient health services: pharmacist daily tour with the specialist doctors and active participation in patient's management; observation of patient's records including prescribed treatment; with determination of any mistake e.g. (doses, interactions, presence of contraindications or cautions); regulation of drugs administration in proper way; helping of specialist doctors to find suitable substitution for unavailable drug; presentation or attending at the scientific lectures about medical treatments and new sorts of drugs. The assessment of these Vital activities (VAs) is presented as value from hundred percent. Regarding the hospitals A and B the study show poor (< 50 %) average results of the pharmacists five vital activities, that was mentioned in the methods above. There is significant defect in the pharmacist’s performance that is multifactorial in origin and assessment activities should be sequenced throughout effective program to produce most applicable resolutions

Table of content: volume:2 issue:1