Table of content

Muthanna Medical Journal

مجلة المثنى الطبية

ISSN: 2226146x
Publisher: Al-Muthanna University
Faculty:
Language: English

This journal is Open Access

About

Muthanna Medical Journal (MMJ) is the official journal of Muthanna Medical College, a semiannual peer-reviewed online and print journal. The MMJ allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional/subject-based repository.
The Journal follows the ICMJE's Recommendations for the Conduct, Reporting, Editing and Publication of Scholarly Work in Medical Journals.

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Contact info

Postal Mail
Muthanna Medical School
Samawah
Tel: 0782542-5669
Email: yousif_ghaly@yahoo.com

Table of content: 2016 volume:3 issue:2

Article
Association of methicillin and vancomycin antibiotics resistance in staphylococcus aureus isolated from wound infection patients

Authors: Mohammed Abdul Reda Yassen
Pages: 74-79
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Abstract

Methicillin-resistant Staphylococcus aureus is the major cause of healthcare-associated bacteremia in most of Hospital and it increased risk of infection, morbidity and mortality especially, when associated vancomycin resistance in same infection. In this study 42 S. aureus were isolated from wound infection patients in Diwaniya hospital and S. aureus was isolated by selective medium out form 50 swab samples. The PCR assay was used for direct detection of methicillin (mecA) and vancomycin (van) antibiotics resistance gene in 42 S. aureus isolates. The results show only 5 isolates (11%) were have single methicillin resistance and there no single vancomycin resistance in all isolates. While the PCR results show there found 3 isolates (7.1%) were have association resistance methicillin and vancomycin resistance. But all methicillin resistance was 12 isolates (19%). In conclusion, we conclude that PCR assay can be used as highly sensitive and specific in detection of methicillin and vancomycin resistance gene, and Vancomycin-resistant can be associated with Methicillin resistance in Staphylococcus aureus isolated from wound infection.


Article
The effect of adding micro zinc oxide filler to heat-polymerizing acrylic resin on some physical properties

Pages: 80-85
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Abstract

Statement of problem: In dentistry, the acrylic resins are the common materials used for fabrication of removable dentures to restore function, appearance, etc. However, such restorative substances have to be lacking some physical properties. The aim of the current study to assess the effect of zinc oxide filler on some physical properties of heat cured acrylic resin. A total of 40 acrylic specimens were fabricated. Depending on the type of test, they were divided into water sorption and porosity groups. For each group, 20 specimens were reinforced with zinc oxide particles at 1% by weight and the others were considered as control. The porosity and water sorption tests were carried out for each specimen. The specimen’s data were analyzed and comparison was made by independent t test. The results showed that there was a slightly reduction in water sorption and porosity after incorporation of zinc oxide filler. In conclusion; the addition of ZnO powder to heat cured acrylic resins affects slightly their physical properties.


Article
Safety and efficacy of ESWL lithotripsy as a primary modality of treatment for upper ureteric stones: A 5-year experience

Pages: 86-93
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Abstract

Urinary stone disease is a major health care problem due to its high prevalence and incidence. The aim of the study is to evaluate the safety and efficacy of ESWL lithotripsy as a primary modality of treatment for upper ureteric stones. From October 2011 to October 2016, 400 patients (300 male and 100 female) with upper ureteral stones were admitted to Al-Diwaniya teaching hospital, urology unit and enrolled in this study, their age range from 18 to 65 years with a mean age of 40 ± 3 years. All patients were evaluated by history, physical examination, laboratory investigation (including urinalysis, full blood count, coagulation profile and renal function tests). The stone size, location, opacity and degree of obstruction were assessed by preoperative radiographic imaging studies, including KUB, ultrasound and computerized tomography (CT scan). The overall stone-free rate at three months was 95% (380/400). Clearance after first sitting was 70% (280/400), after second sitting was 20% (80/400) and after third sitting was 5% (20/400). Clearance of stone in patients with stone size ≤ 1 cm was 97% (388/400), and in patients with stone size > 1cm was 5% (340/400). Five per cent (20) of cases did not have successful outcome. In conclusion, the results of our study show that ESWL as a primary modality for upper ureteric stones treatment has an overall success rate of 95%. Success rate drops with increasing size of stone, duration of stone in ureter, and no anesthesia is required.


Article
Effect of plasmapheresis on panel reactive antibodies in kidney transplant candidates

Authors: Sahban Al Mallah
Pages: 94-106
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Abstract

Panel reactive antibody (PRA) is one of the tests used to assess the degree of sensitization before kidney transplant, and plasmapheresis is one of the measures used for desensitization. In this study we assessed the role of plasmapheresis as a desensitizing measure. This study was conducted in the medical city complex in Baghdad, Iraq; for the whole year 2012, enrolling patients attending the lab. of the nephrology and kidney transplant centre recording their PRA readings before and after plasmapheresis ( for those with PRA >=20%); in addition to date, age, sex, blood group and whether or not they had been previously transplanted. Data were analyzed using chi square and pair T-test. A 179 patients enrolled, 35 (19.6%) of them had positive PRA test, 12 reading were 20% or more; and were rechecked after plasmapheresis with no significant difference. A part from history of previous transplant; none of the other factors showed significant association with PRA levels In conclusion, no significant effect of plasmapheresis on the levels of PRA.


Article
The role of ultrasound in the diagnosis of carpal tunnel syndrom

Authors: Ali Taha Hassan Al-Azzawi
Pages: 107-116
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Abstract

The aim of this study is to confirm the accuracy of sonography in the diagnosis of the carpal tunnel syndrome by measuring the cross-section area of the median nerve. A prospective study of 80 patients suspected of having carpal tunnel syndrome was underwent sonography at Al-Hussein Teaching Hospital in Samawa city from 1/1/2015 to 1/1/2016. The cross sectional area of the median nerve was measured at three levels, immediately proximal to carpal tunnel inlet, at carpal tunnel inlet and carpal tunnel outlet. The average value was measured. The flexor retinaculum was used as a landmark to margin of the carpal tunnel. Sensitivity and specificity of sonography were revealed as (89%) and (90%) respectively. All patients were sent for electro-diagnosis as standard reference test to compare with the values of sonography. The study proved that the sonography is sensitive but in compared with the electrodiagnosis has lower specificity. Demographic information including age, sex, side of the limb affected, and duration of the symptoms and grading of severity of the cases of the carpal tunnel syndrome were revealed. The study revealed associated disorders with the carpal tunnel syndrome such as diabetes mellitus (7 patients), pregnancy (5 patients), trauma (3 patients), hypothyroidism (1 patient), rheumatoid arthritis (1 patient), dorsal wrist ganglia (2 patients), and history of Colles’ fracture (2 patients), obese patient (12 patients), workers at manufacturing industries (3 patients) and two writers. The study proved that the sonography is easily performed, painless, rapid and available for the diagnosis of the carpal tunnel syndrome as adjuvant to electro-diagnosis but is not as substitute to it.


Article
Coronary angiographic findings in patients with positive family history of premature coronary artery disease

Authors: Abdulameer Aboodib
Pages: 117-121
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Abstract

A family history of premature coronary artery disease is an independent and established risk factor for CAD. A total sample of 657 Iraqi patients with coronary artery disease who submitted to routine coronary angiography in our cardiology center, only 72 patients with a positive family history of premature coronary disease were enrolled in this study. Hypertension and left anterior descending artery occlusive disease were more prevalent in 64% of patients with a positive family history of premature CAD (64 %). When comparison had been made between male and female with a positive family history of premature CAD. Smoking and single vessel disease were more frequently encountered in male patients (p value =0.001 and 0.05 respectively). In conclusion and recommendations: screening of first degree relatives of patients with a positive family history of premature CAD and intensive management of other cardiac risk factors particularly hypertension and smoking are required.


Article
Cardioprotective effect of tetrahydroisoquinoline following I/R through down-regulation of ICAM-1 signaling pathway

Authors: Bassim I Mohammad
Pages: 122-132
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Abstract

Myocardial injury caused by ischemia followed by reperfusion mediates a complex series of inflammatory response that reduces the benefit of medical interventions, such as percutaneous coronary intervention, and coronary bypass surgery. The objective of this study was to investigate the potential cardioprotective effect of tetrahydroisoquinoline against myocardial I/R, and the mechanistic pathway of this effect. A total of 32 adult (4 – 6 months) male Albino-Webster mice were randomly divided into 4 equal groups: (1) sham-control group, (2) ischemia and reperfusion (I/R) operated group, (3) vehicle-treated group, and (4) tetrahydroisoquinoline (TIQ)-treated group receiving TIQ 10 mg/kg once daily shortly before I/R. ELISA technique was performed to measure myocardial and plasma levels of cytokines (IL-1β, IL-6, and TNF-α), chemokine (MCP-1), and cTn-I. In addition, the activity of ICAM-1 was analyzed by Western blot. Further, the ischemia changes and myocytes injury were examined by histopathological assessment using hematoxylin and eosin (H&E) stain. The results demonstrated that treatment with TIQ markedly improved left ventricular function (LVF) in mice, and reduced plasma level of cTn-I as marker of cardiac injury. Moreover, the effects of TIQ was associated with attenuations in both chemokine and cytokines expression following I/R, that accompanied by down-regulation of activation of ICAM-1 pathway. In conclusions, this study revealed that treatment with TIQ was able to improve LV function after I/R. This improvement was associated with reductions of inflammatory response and activity of ICAM-1, as mechanistic link of its action.


Article
“Conservative treatment for sciatica compare with surgical intervention: a multi-center cohort clinical study” is locked Conservative treatment for sciatica compare with surgical intervention: a multi-center cohort clinical study

Pages: 133-138
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Abstract

The objective of this study is to compare between conservative and surgical intervention in patients with low back ache. A cohort clinical retrospective-prospective study is enrolling 75 patients with low back ache and diagnosed as sciatica in multi-center (Baghdad and Muthanna). The outcome of both procedures depends on the following measures: neurological deficit, Lasègue test, Sciatica Bothersomeness Index, contralateral Lasègue test. Paired t-test applied for efficacy within the group and Chi-square test to compare the efficacy of two groups. After 6 months there was significant difference between operated and non-operated patients related to Sciatica Bothersomeness Index (p = than 0,01), Lasègue test (p=0,001), neurological deficit (p = 0,01) and leg and back pain depending on the activity (p=0,002). There was no difference statistically difference between the groups related to contralateral Lasègue test (p=0,206). In conclusion, we expended formerly accepted operative indications. There were better treatment results in the surgical operated group. A fast reduction of symptoms is the main advantage of the operative treatment strategy. Patients whose pain is treated in process that is acceptable for them may decide to postpone surgery. Patient’s preference for the type of treatment is crucial for an ultimate surgical decision in cases without widespread neurological deficits.


Article
The effect of pulmonary tuberculosis and short course treatment on some hormones of patients women

Pages: 139-146
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Abstract

The objective of this study was to investigate the changes that occurred on some hormones of patients women with pulmonary tuberculosis and the side effects of anti-tuberculosis drugs which used in Directed Observed Treatment Short course (DOTS) on some hormones. The study included follow-up (100) cases from the women who suffer from Pulmonary tuberculosis disease (before treatment ,after two months of treatment and after six months of treatment) , and the results were compared to control group composed of (100) healthy women , the patients groups and control group ages were ranged (21-60)years old .The results of this study showed non-significant differences at (p>0.05) in TSH levels of all groups patients as compared between them or as compared with control. also the results indicated non-significant differences at (p>0.05) in T4 and T3 levels of before treatment patients group as compared with control but the results indicated a significant decrease at (P<0.05) in T4 and T3 levels of after treatment patients groups (after two months of treatment group and after six months of treatment group) as compared with the control group or as compared with before treatment patients group. Also the results showed a significant decrease at (P<0.05) in T4 and T3 levels of after six months of treatment patients group as compared with after two months of treatment patients group. Our results indicated a significant decrease at(P<0.05) in EPO level of before treatment patients group as compared with control group but the results recorded non-significant differences at (p>0.05) in EPO levels of after treatment patients groups (after two months of treatment group and after six months of treatment group) as compared with control group. Also the results recorded non-significant differences at (p>0.05) in EPO levels of after six months of treatment patients group as compared with after two months of treatment patients group

Keywords

Pulmonary tuberculosis --- Short course treatment --- TSH --- T4 --- T3 --- EPO --- ELISA

Table of content: volume:3 issue:2