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Article
Some Immunological Evaluations of Propolis in Albino Male Mice

Author: Ali H. Ad'hiah
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2007 Volume: 49 Issue: 1 Pages: 121-125
Publisher: Baghdad University جامعة بغداد

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Abstract

Propolis is a complex resinous bee product that has a wide range of biological activities. In thepresent investigation, two oral doses (10 and 20 mg/kg/day) of propolis (ethanol extract) wereevaluated immunologically in albino male mice (80 animals) through three types of experiments. Inthe first, the propolis was tested alone, while in the second and third experiments, propolis was givenbefore and after the immune suppressive drug MMC (pre- and posttreatments, respectively). The three experiments were paralleled with three negative controls, inwhich the propolis was replaced with distilled water. In the first experiment, the dose 10 mg/kg ofpropolis enhanced the parameters investigated, and a significant increase was observed in the totalcount of leucocytes (10.7 vs. 7.8 x 103 cells/cu.mm.blood), lymphocytes (7.0 vs. 5.3 x 103cells/cu.mm.blood), neutrophils (2.9 vs. 2.1 x 103 cells/cu.mm.blood), monocytes(0.5 vs. 0.3 x 103 cells/cu.mm.blood) and eosinophils (0.3 vs. 0.1 x 103 cells/cu.mm. blood), PI (15.2vs. 10.8%), PFC (72 vs. 38%), AR (0.84 vs. 0.57 mm) and DTH (0.68 vs. 0.40) as compared tonegative controls. Much more enhancements were observed in the dose 20 mg/kg. In the second andthird experiments, a similar picture was drawn in the interaction of propolis (pre- and posttreatments)with MMC, in which the propolis extract was able to modulate the immune suppressiveeffect of MMC, and this was dependent on the type of treatment and dose, and again, the dose 20mg/kg was more effective in this respect.Key words and Abbreviations: Arthus reaction (AR), Delayed type hypersensitivity reaction (DTH),Mitomycin C (MMC), Phagocytic index (PI),Plaque forming cells (PFC), Propolis and Sheep red blood cells (SRBC).


Article
Acetaminophen Mimics the Action of Salbutamol in Relaxing Gravid Human Uterus - In - Vitro

Author: Mahdi I. Hilmy
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2007 Volume: 49 Issue: 1 Pages: 126-129
Publisher: Baghdad University جامعة بغداد

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Abstract

Management of preterp'labour generally treated by salbutamol even with some expected disturbing -maternal pulmonary oedema , respiratory distress and cardiovascular side effects and neonatal low-sized and cellularity of thymus and lymph nodes . This demands finding a substitute free of these side effects . Initially, acetaminophen was tested on rats uterine horns and on pregnant rats and reported an effective relaxation of the uterine horns and profound delay in parturition . These results jestified an in-vitro study on strips of gravid human uterus ruptured during difficult labour. Acetaminophen (50 mg) reduced tension by 50% which was comparable decrease in tension when 5 gg of salbutamol was added. Profound drop in tension when adjunct use of both drugs, while repeated three doses of 50 mg acetoaminophen were added separately resulted in corresponding drops in tesion down to below resting level . These findings encouraged future clinical trials on threatened women with abortion since the use of acetaminophen in the usual dosage is effective tocolytic agent without any maternal side effect but with mild possible neonatal lung congestion as a result of transient narrowing of ductus arteriosis especially in advanced gestation age.


Article
Placental Localization and its Influence on Presentation of the Fetus in the Uterus
المشيمة التعريب وأثره على تقديم الجنين في الرحم

Author: Maad S. Al Adami
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2007 Volume: 2 Issue: 132 Pages: 27-31
Publisher: Tikrit University جامعة تكريت

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Abstract

This prospective study was carried out from the period of October 2004 to October 2005, in Al Kadhmiya Teaching Hospital Baghdad/ Iraq, to establish the influence of placental localization on the fetal position in the uterus and to evaluate the influence of placental localization on fetal position in uterus after exclusion of uterine and fetal anomalies. One hundred primigravida women were involved in this study, 50 of them with cephalic presentation of their fetus and another 50 with breech presentation, localization of the placenta was determined by ultrasonography or during caesarean section. The cornu-fundal localization of the placenta was found in 4.8 % of cephalic presentation and 62% with breech presentation. Placenta previa or low insertion of the placenta was found in 3.2% of breech presentation and none of cases with cephalic presentation. The study conclude that the localization of the placenta may influence the fetal position in the uterus.

وقد أجريت هذه الدراسة استطلاعية عن الفترة من أكتوبر 2004 إلى أكتوبر 2005، في تدريس مستشفى Kadhmiya بغداد / العراق، لإنشاء تأثير توطين المشيمة على وضع الجنين في الرحم، وتقييم تأثير توطين المشيمة في وضع الجنين في الرحم بعد استبعاد الحالات الشاذة الرحم والجنين. وقد شارك مائة نساء خروس في هذه الدراسة، قرر 50 منهم مع عرض رأسي من جنين وآخر 50 مع المجيء المقعدي، توطين المشيمة بواسطة الموجات فوق الصوتية أو خلال عملية قيصرية. تم العثور على توطين قرن، قاعي من المشيمة في 4.8٪ من العرض الرأسي و 62٪ مع مجيء مقعدي. تم العثور على المشيمة المنزاحة أو الإدراج منخفضة من المشيمة في 3.2٪ من المجيء المقعدي وأيا من الحالات مع عرض رأسي. دراسة تخلص إلى أن التعريب من المشيمة قد تؤثر على وضع الجنين في الرحم.

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