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Article
Prevalence of anti-hepatitis C virus antibodies among blood donors and risky groups in Diyala

Author: Abdul-Razak S. Hassan
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2008 Volume: 50 Issue: 4 Pages: 467-470
Publisher: Baghdad University جامعة بغداد

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Abstract

Objective: To determine the prevalence of hepatitis C virus (HCV) infection among blood donors and risky population in Diyala province.
Materials and methods: In this retrospective study, the records of HCV screening and confirmatory tests were reviewed for the period 1996-2001.Third generation Enzyme-linked immunosorbant assay (ELISA) and Enzyme immunoblot assay were used as screening and confirmatory tests respectively.
Results: The prevalence of HCV infection among blood donors was 0.15%, with the highest in 1997. The highest prevalence rates were found among multiple blood recipient; hemophilia, thalassemia and hemodialysis patients (27.3%, 16.9% & 14.3%) respectively. Whereas, the patients with chronic hepatitis B infection and those with acute icteric hepatitis showed slightly elevated prevalence (2.9% & 2.1%) respectively. The overall prevalence in the province was 9.9/105 population. The mean age of infected patients was 29.7 years and the male: female ratio was 3:1.
Conclusion: The prevalence of HCV infection in Diyala population is relatively low. However, the HCV infection is concentrated in certain risky groups, particularly multiple blood recipients.


Article
Screening of Hepatitis B- and C- Viral Markers in Iraqi Patients with Proteinuria

Author: Abdul Hadi K . Hussain
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2008 Volume: 7 Issue: 4 Pages: 362-368
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:Viral hepatitis may lead to nephropathy as one of its multiple extra hepatic manifestations. Symptomatic proteinuria as detected by dipstick, and qualitative urine collection are simple tests in practice as well as useful cardinal test of underlying renal abnormalities. The aim of this study was to elucidate the impact of hepatitis B virus (HBV) and/or hepatitis C virus (HCV) infections on the occurrence of symptomatic proteinuria amongst adults and pediatrics.PATIENTS & METHODS :A prospective study included (143) adult and pediatric Iraqi patients presented with symptomatic proteinuria, and 108 (age- and sex-matched) apparently healthy individuals (as control group) who were serologically screened for HBV & HCV markers using third generation Enzyme linked immunosorbent assay (ELISA) techniques, screening for HIV by ELISA and other related immunological and biochemical profile.RESULTS :It was found that the prevalence of hepatitis B surface antigen (HBsAg), anti hepatitis B core antibody (anti-HBc-IgM), anti hepatitis B surface antibody (anti-HBs) and anti hepatitis C antibody (anti-HCV) in the proteinuria group as compared to control group, were (7.0% vs. 0.9%, P<0.05) for HBsAg, (2.8% vs. 0% ,P>0.05) for anti-HBc-IgM, (20.3% vs. 23.1%, P>0.05) for anti-HBs antibody, and (6.3% vs. 0%, P<0.01) for anti-HCV.CONCLUSION :Our study demonstrated a significant association between proteinuria and HCV, and HBV infection in the adult and pediatric population. The interpretation of serological patterns of viral hepatitis markers in patients with newly diagnosed proteinuria are important, it might suggest that detailed urinalysis and qualitative urine protein assessment is mandatory when managing patients with HCV or with HBV infections.


Article
Hepatitis C virus infection and abortion among pregnant women in Mosul city
عدوى فيروس التهاب الكبد C والإجهاض بين النساء الحوامل في مدينة الموصل

Authors: Sumaya T. Saihood --- Nadya I. Salih --- Israa H. Saadoon
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2008 Volume: 1 Issue: 141 Pages: 161-164
Publisher: Tikrit University جامعة تكريت

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Abstract

Infection with HCV is a major public health problem and is of particular concern duringpregnancy. Identification of transmission risk factors is essential for the development ofappropriate interventions. The aim of this study was to evaluate infection with HCV in pregnantwomen and to identify the correlation between HCV infection and abortion. The current studyincluded 875 pregnant women attended to three hospitals in Mosul City (Al-Batool, Al-Khansaa,and General Mosul Hospital) during the period from the beginning of July 2007 to the end ofSeptember 2007. The study revealed that infection with hepatitis C virus (HCV) was found in 45out of 875 pregnant women (5.14 %). There was significant correlation between HCV infectionand abortion. The risk of HCV infection increased with increasing number of abortions.

عدوى فيروس (سي) هو مشكلة صحية عامة رئيسية ومصدر قلق خاص خلال الحمل. تحديد عوامل الخطر انتقال أمر أساسي من أجل تطوير التدخلات المناسبة. وكان الهدف من هذه الدراسة لتقييم الإصابة بفيروس الكبد الوبائي في الحوامل نساء والتعرف على العلاقة بين فيروس التهاب الكبد الوبائي، والإجهاض. الدراسة الحالية وحضر وشملت 875 امرأة حامل الى ثلاثة مستشفيات في مدينة الموصل (سورة بتول، الخنساء، والجنرال مستشفى الموصل) خلال الفترة من بداية يوليو 2007 الى نهاية عام سبتمبر 2007. وكشفت الدراسة التي تم العثور عليها مع عدوى فيروس التهاب الكبد الوبائي (سي) في 45 من أصل 875 امرأة حامل (5.14٪). كان هناك ارتباط كبير بين فيروس التهاب الكبد الوبائي والإجهاض. تزيد من خطر الإصابة بعدوى هذا الفيروس مع تزايد عدد حالات الإجهاض.

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