research centers


Search results: Found 2

Listing 1 - 2 of 2
Sort by

Article
The possible association between Chlamydia pneumoniae infection and asthma.

Authors: Haider Ahmed Shemran --- Haider S. Kadhim --- Mahmood Sh. Al-Zaidi
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: PISSN: 00419419 / EISSN: 24108057 Year: 2010 Volume: 52 Issue: 3 Pages: 316-317
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract


Background: Many etiological factors have been implicated in the pathogenesis of Asthma like; viruses, bacteria and Chlamydia pneumoniae. This study focuses on the role of Chlamydia pneumoniae in asthma pathogenesis.Patients and Methods: The detection of Anti-Chlamydia pneumoniae antibodies IgA, IgM and IgG in patients by ELISA, for 35 patients, 18 asthmatic patients, 12 patients with chest infection with no history of asthma, and 5 apparently healthy as control subjects.
Results: The results showed that 80% and 70% of the patients were negative for anti- Chlamydia pneumonia antibodies IgA and IgM respectively, while significantly (p<0.05) high number (73%) of patients were positive for IgG, of which significant number (p<0.05) of them, 63% were asthmatic and 36% were non-asthmatic chest infection.
Conclusion: this study may support the association between Chlamydia pneumoniae and asthma.


Article
Prevalence of anti-Chalmydial Immunoglobulins in pregnant women in Al-Kadhimiya Teaching Hospital

Authors: Suhad M. Al-Hamdani --- Haider A. Shemran --- Haider S Kadhim --- Hassan Yasser
Journal: Journal of College of Education مجلة كلية التربية ISSN: 18120380 Year: 2010 Issue: 1 Pages: 59-70
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

Background: The sexually transmitted microorganism Chlamydia trachomatis causes a medical problem world wide, especially for pregnant women as this infection may lead to different complications in pregnancy.Patient and Methods: In this study, 57 pregnant women with suspected Chlamydial infection were included from consultant clinic Al-Kadhimiya teaching hospital in Baghdad, with 17 pregnant women as control group. ELISA tests were done to detect the level of anti-chlamydial antibodies, IgM, IgG and IgA.Results: In our study we found IgM seropositivity to C.trachomatis in 85.96% of patients and 14.03 % of controls and similar results were found regarding IgG seropositivity in patients and control groups. IgA seropositivity to C.trachomatis was positive in 59.64% of patients and 40.35 % of controls. In our study we also found higher rates for seropositivity regarding antichlamydial antibodies of IgG, IgM and IgA types in patients with a history of more than one abortion compared to those who have negative history of abortionConclusion: Antichlamydial antibodies of IgA, IgG and IgM types were found to be elevated in the study group and this may reflect the incidence of infection of Chlamydia trachomatis in our patients. Moreover it may reflect the relation of infection to repeated abortion as there was a high level of antichlamydial antibody in patients with history of more than one abortion.

المقدمة: الكائن المجهري كلاميديا التراخومية والمنقول بالاتصال الجنسي يسبب مشاكل طبية عديدة في معظم انحاء العالم, لاسيما عند النساء الحوامل حيث ان هذه الاصابة قد تسبب مضاعفات عديدة ومختلفة للحوامل.المرضى وطريقة العمل: شملت هذه الدراسة 57 أمرأة حامل يشتبه بإصابتها بالكلاميدية مع 17 أمرأة حامل خالية من الاصابة. تم الفحص والتشخيص في العيادة الاستشارية للنساء الحوامل في المستشفى الكاظمية التعليمي في بغداد, حيث اجري فحص الاليزا (ELISA) لمعرفة مستوى مستضدات الكلاميديا من الانواع (A, G, M) في مصل الدم.النتائج: بينت النتائج بأن هناك 85.96% ارتفاع في مستوى مستضد (IgM) في المرضى مقارنة مع 14% لمجموعة السيطرة وكذلك نتائج مشابهة لمستضد (IgG). بينما نتائج مستضد (IgA) كانت 59,64% مرتفعة لدى المرضى و40.35% لمجموعة السيطرة. كما وأظهرت النتائج بأن هناك ارتفاع في نسب المستضدات الثلاثة للمرضى الذين لديهم تاريخ إجهاض متكرر بالمقارنة مع المرضى الذين ليس لديهم إجهاض سابق.الاستنتاجات: إن مستضدات الكلاميديا التراخومية مرتفعة في مجموعة البحث وهذا ممكن ان يعكس ارتفاع مستوى الإصابة بهذه الجرثومة. كما ويمكن أن نستنتج بأن قد يكون هناك ارتباط غير مباشرة بين نسبة الإصابة وعدد تكرار الإجهاض للمرضى المصابين.

Keywords

Chlamydia trachomatis --- IgG --- IgM --- IgA --- ELISA

Listing 1 - 2 of 2
Sort by
Narrow your search

Resource type

article (2)


Language

English (2)


Year
From To Submit

2010 (2)