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Article
A study on the Prevalence of Dyslipidemic Disorder Among Residents of Karbala City

Authors: Hedef Dhafir El-Yassin --- Zainab Abdul Razak Al- Sharifi --- Suhair Al-Jeboori
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2011 Volume: 10 Issue: 3 Pages: 358-366
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:Dyslipidemia is a common health problem.OBJECTIVE:The present study was to estimate the prevalence of dyslipidemia as defined by the NCEP ATP3 criteria among people living in Karbala city.SUBJECTS AND METHODS:The investigations were performed on a sample of 130 subjects selected arbitrarily from those attending the public clinic in AL- Hussainy teaching hospital in Karbala for consultation and from some subjects accompanying the patients. Fasting blood samples for routine lipid analyses from each subject were obtained after informing them about the project and having their approval.RESULTS:In this sample of subjects it was found that 72.3% of them had a plasma TC level lower than 200mg/dl. This study also determined a prevalence of hypertriglyceridemias in 23.3% of study subjects who have a borderline TG level. The prevalence of high and very high TG among them were 6.9% and 4.4% respectively. The frequency of LDL-C levels above 160 mg/dl was found to be about 1% of the sample. Borderline levels of LDL-C was found in 7.3%of the sample. In the meantime the prevalence of low HDL-C levels in this study was found to be 39.2% of the subjects who had a serum level of HDL-C less than 40mg/dl.CONCLUSION:In conclusion this study demonstrated a very high prevalence of dyslipidemia among Iraqi adult subjects living in Karbala city. A public health strategy for prevention, detection and treatment of this disorder is neede


Article
Evaluation of Changes in Levels of Serum Selenium in Diabetic Pateints and in Diabetic Pateints with Cardiovascular Disease

Author: Khawla Abdul Kareem Kasar
Journal: Al-Nahrain Journal of Science مجلة النهرين للعلوم ISSN: (print)26635453,(online)26635461 Year: 2011 Volume: 14 Issue: 2 Pages: 58-66
Publisher: Al-Nahrain University جامعة النهرين

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AbstractSelenium, an essential micronutrient, may affect several cardiometabolic risk factors, such as glucose homeostasis and lipid concentrations. The aim of this study is to examin the relation between serum selenium concentrations with serum lipids in diabetic patients and in diabetic patients with cardiovascular diseases (CVD).A case control study conducted in the National Diabetes Center, College of Medicine at Al-Mustansiryia University. Fasting glucose, total cholesterol, high density lipoprotein–cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), and very low density lipoprotein-cholesterol (VLDL-C), HbA1c and Serum selenium were determine. Diabetes mellitus (n=256) divided into tow groups, group I (n=156) diabetic patients and group II (n=100) diabetic patients complicated with CVD. Normal healthy subjects were taken as control (n= 100).In the present study a significant decrease in selenium levels was found in patients groups compared to control also there is decrease in selenium levels of diabetic patients with CVD (group II) compared with diabetic patients (group I). These findings indicate that the decrease in serum selenium was associated with elevated serum concentrations of fasting blood glucose, total cholesterol, LDL-C, VLDL-C, triacylglycerols and duration of diabetes. In general despite their classification according to sex or diabetes type highly negative correlations (p<0.0001) were found with linear regression equations between fasting serum selenium concentration and HbA1c in patients group II. In conclusion the significant reductions in the level of selenium in diabetic patients may be response on the developing t he diabetic to anther disease like CVD.

الخلاصةالسلنيم من العناصر المهمه في عمليات الاكسدة في الجسم و من العوامل المؤدية الى أمراض اخرى عند مرضى السكري ومن اهمها امراض القلب .لذالك اجريت هذه الدراسة في المركز الوطني لمرض داء السكري في كلية الطب-الجامعة المستنصرية وقد تم قياس مستوى عنصر السلنيم في مصل الدم لمرضى السكري (156) ومجموعة اخرى من مرضى السكري مصابون بامراض قلبية (100) ومقارنتهم بمجموعه ثالثة من الاصحاء (100) مع مراعت تقارب العمر والجنس بين المجموعتين من مرضى السكري ومجموعة الاصحاء. وبلاضافة الى عنصر السلنيم قد تم قياس كل من السكر الصائم والدهون ونسبة الهيموكلوبين.وقد اضهرت النتائج نقصان في مستوى عنصر السلنيم في المجموعتين من مرضى السكري مقارنتا بالاصحاء. وقد لوحضى ان مستوى عنصر السلنيم اقل في مرضى السكري المصابون بامراض قلبية (المجموعة الثانية) مقارنتا بمرضى السكري (الجموعة الاولى). وبغض النظر عن تقسيم المرضى المصابين بداء السكري (حسب الجنس ونوع الداء، وجدت علاقة خطية سالبة الارتباط عالية الاهمية بين مستوى عنصر السلنيم ونسبة هيموكلوبين الصائم (HbA1c) عند المرضى المصابين بداء السكري وامراض قلبية (المجموعة الثانية). بلاضافة الى ذلك لقد وجدة علاقة مهم بين مستوى عنصر السلنيم و كل من السكر الصائم و الكولسترول وTG والدهون قليلة الكثافة LDL في المجموعة الاولى. اما بالنسبة للمجموعة الثانية فقد وجد علاقة مهمة بين مستوى عنصر السلنيم و كل من السكر الصائم و الكولسترول. الاستنتاج من هذه الدراسة ان النقصان الملحوض في مستى عنصر السلنيم في مرضى السكري هو من اسباب تطور المرض واصابت المرضى بامراض اخرى من اهمها امراض القلب.


Article
Changes of Liver Enzymes in Coronary Heart Disease

Authors: Salman K. Ajlan --- Yasin A. Baqir
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2011 Volume: 4 no 1 Issue: 9 Pages: 994-1001
Publisher: Kerbala University جامعة كربلاء

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background : Coronary heart disease is one of the leading causes of morbidity and mortality elsewhere in the world . An association between liver enzymes and coronary heart disease is suggested.Objective: To evaluate the changes in liver enzymes, Alanine aminotransferases andaspartate aminotransferases in patients with coronary heart disease.Methods: The study included 60 patients with coronary heart disease (41 males and 19 females), and 40 control subjects (25 males and 15 females) from Basrah, Iraq. Alanine aminotransferase, aspartate aminotransferase, lipid profile and fasting blood glucose levels were determined.Results: alanine aminotransferase , aspartate aminotransferase, fasting blood glucose, totalcholesterol, triglycerides, and low density lipoprotein- cholesterol levels were significantlyhigher among coronary heart disease patients compared to controls (P<0.001), while highdensity lipoprotein- cholesterol level was significantly lower among patients with coronaryheart disease in comparison to controls (P<0.001). Alanine aminotransferases revealed asignificant positive correlation with triglycerides (P=0.006), and significant negativecorrelation with high density lipoprotein- cholesterol (P= 0.031) and no significantcorrelations with body mass index, blood pressure, and other biochemical parameters(P>0.05). On the other hand, aspartate aminotransferases showed significant positivecorrelations with total cholesterol (P=0.009), triglycerides (P=0.025) and low densitylipoprotein- cholesterol (P=0.042), and no significant correlations with other physiologicaland biochemical parameters (P>0.05).Conclusions: A strong association exists between changes in liver enzymes, alanine aminotransferase and aspartate aminotransferase and coronary heart disease. These enzymes could be included within the increasing list of coronary heart disease risk factors. Also, they might have prognostic significance and a predictive value in coronary heart disease complications.Key words: Coronary heart disease, liver enzymes, lipid profile.


Article
Effects of simvastatin on lipid profile, atherogenic index and serum transaminases in hyperlipidemic patients
آثار سيمفاستاتين على البروتين الدهني ومؤشر تصلب الشرايين و مصل transaminases في مرضى شحميات الدم

Authors: Ari Aziz Salih --- Showan D. Husain
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2011 Volume: 15 Issue: 2 Pages: 29-33
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Background and objectives: Hyperlipidemia is characterized by increased concentrations of lipids including triglycerides, total cholesterol, low density lipoproteins, very low density lipoproteins in the blood and some times decreased high density lipoproteins .Many drugs have been used for treatment of this disorder. The present study was designed to estimate the effects of simvastatin on lipid profile, atherogenic index, transaminases, creatinine, uric acid and alkaline phosphatase.Methods: This study covered 70 subjects, they were divided into two groups, the first group included 45 hyperlipidaemic patients which were treated with 20mg simvastatin and second group included 25 normal subjects. After 12 hours fasting, serum lipid profile, transaminases; alkaline phosphatase, uric acid and creatinine were measured for the patients in 3 intervals before treatment, after 8 weeks and 16 weeks of treatment, and one time for normal subjects.Results: : After therapy, simvastatin showed a significant reduction in serum (TC, TG, LDL, VLDL and atherogenic index) and also, significant rise in HDL noticed, by performing a comparison between the group before treatment, and groups after treatment.Serum ALT, AST and ALP were significantly increased but were still within normal levels.Insignificant effect was observed from serum creatinine, uric acid and also body mass index by performing a comparison between group before treatment and groups after treatment.Conclusions:Simvastatin was effective in controlling lipid profile and atherogenic index, with no significant abnormality in liver functions.


Article
The Association Between Leptin with Lipid Profile and Troponin in Acute Myocardial Infarction Patients

Authors: lmmmA Esmaeel Ibrahim --- Hadef Dhafer EL-Yassin --- Hamid Kareem Sachit AL-Janabi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2011 Volume: 10 Issue: 3 Pages: 332-338
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT :BACKGROUND:Fat cells, are the cells that primarily compose adipose tissue, specialized in storing energy as fat. Adipose tissue also serves as an important endocrine organ by producing hormones such as leptin, resistin, and the cytokine. Leptin is a protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. Acute Myocardial Infarction (AMI), is the interruption of blood supply to part of the heart, causing some heart cells to die.OBJECTIVE:To investigate the levels of leptin and its effect on lipid profile level in Acute Myocardial Infarction.SUBJECTS AND METHODS:The study included 50 patients with Acute Myocardial Infarction and forty healthy subject as control group. leptin and lipid profile levels were measured.RESULTS:The levels of leptin were significantly elevated in female patients group with(p=0.002), in male patients group(p=0.018) and in total patients group (p=0.001), cholesterol and LDL-C were significantly elevated with (p<0.001), while HDL-C was significantly lower with (p<0.001), there was positive correlation between leptin with , cholesterol LDL-C, triglyceride and VLDL, and there was negative correlation between leptin with HDL in acute myocardial infarction patients.CONCLUSION:Leptin negatively correlated with HDL and positively correlated with triglyceride and LDL this relation make this hormone act as atherosclerotic factor.


Article
Level of Resistin in Acute Myocardial Infarction Patients and its Relation to Lipid profile and Cardic Troponin I

Authors: lmmmA Esmaeel Ibrahim --- Hadef Dhafer EL-Yassin --- Hamid Kareem Sachit AL-Janabi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2011 Volume: 10 Issue: 4 Pages: 430-435
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT:BACKGROUND:Inflammatory responses are involved in the initiation and progression of atherosclerotic plaques. Myocardial Infarction (MI) is most commonly due to occlusion of a coronary artery following the rupture of a vulnerable atherosclerotic plaque. It has been suggested that the adipose tissue may play an important role in mediating this chronic inflammatory process. Resistin is a cysteine-rich polypeptide that is expressed at relatively lower levels in human adipocytes but higher levels in macrophages. Troponin is found in cardiac muscle and used for diagnosis of AMI.OBJECTIVE:To investigate the level of resistin and its effect on lipid profile and Troponin I levels in acute myocardial infarction patients.SUBJECT AND METHODS:The study included 50 patients with AMI and forty healthy subjects as control group. In this study resistin , lipid profile and Troponin I were measured.RESULTS:The levels of resistin, cholesterol, LDL-C were significantly elevated with (p<0.001), while HDL-C was significantly lower with (p<0.001), there was positive correlation between resistin with cholesterol, LDL-C, triglyceride and VLDL, while there was negative correlation between resistin with HDL in acute myocardial infarction.CONCLUSION:There was a significant increase in resistin level, in acute myocardial infarction patients and this increase may be related to inflammation. Resistin negatively correlated with HDL and positively correlated with triglyceride and LDL this relationship makes us consider this hormone as possible atherosclerotic factor


Article
Serum lipid profile in Psoriasis: a controlled study

Author: Ahmed Abdul-Aziz Ahmed. احمد عبد العزيز
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2011 Volume: 1 Issue: 171 Pages: 38-42
Publisher: Tikrit University جامعة تكريت

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Psoriasis is an inflammatory dermatosis that is characterized with hyperproliferation of keratinocytes and inflammatory infiltration in the epidermis and dermis. The high prevalence of atherosclerosis has been reported in psoriatic patients. High serum lipid level has been suggested in the pathogenesis of this phenomenon. In this study, our purpose was to compare the lipid profile in psoriatic patients with non-affected persons. This study was designed and conducted as a case-control assay with 19 patients in the first group and24 cases as control groups. The lipid profile, including serum level of triglyceride, cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL), were assessed in both groups. The patient group consisted of 19 (6 male and 13 female )and control group consisted of 24cases (11 male and 13 female). The serum triglyceride, and LDL was significantly higher in psoriatic patients (P < 0.05).
CONCLUSION: This study, like previous assays, shows that high serum lipid level is significantly more common in psoriasis. This fact may be responsible for higher prevalence of cardiovascular accident in psoriatic patients. It may be useful to do early screening and treatment of hyperlipidaemia in psoriasis to prevent the atherosclerosis and its complications.

الصدفية هو مرض جلدي التهابي التي تتميز مع المفرط لمن الخلايا الكيراتينية وتسلل التهابات في البشرة والأدمة. تم الإبلاغ عن ارتفاع معدل انتشار مرض تصلب الشرايين لدى مرضى الصدفية. وقد اقترح ارتفاع مستوى الدهون في الدم في التسبب في هذه الظاهرة. في هذه الدراسة، وكان هدفنا للمقارنة بين الدهون لدى مرضى الصدفية مع المنظمات غير الأشخاص المتضررين. وقد تم تصميم هذه الدراسة والتي أجريت على أنه فحص الحالات والشواهد مع 19 مريضا في المجموعة الأولى and24 الحالات باعتبارها مجموعات المراقبة. وجرى تقييم الوضع الدهون، بما في ذلك مستوى مصل الدهون الثلاثية والكوليسترول والبروتين الدهني منخفض الكثافة (LDL)، والبروتين الدهني عالي الكثافة (HDL)، في كل من المجموعتين. وتألفت المجموعة المريض من 19 (6 من الذكور والإناث 13)، وسيطرة مجموعة تتألف من 24cases (11 من الذكور والإناث 13). كانت الدهون الثلاثية في الدم، والكولسترول أعلى بكثير في المرضى الذين يعانون الصدفي (P <0.05). الخلاصة: هذه الدراسة، مثل فحوصات السابقة، تبين أن ارتفاع مستوى الدهون في الدم بشكل ملحوظ أكثر شيوعا في مرض الصدفية. قد يكون هذا الواقع تكون مسؤولة عن ارتفاع معدل انتشار حادث القلب والأوعية الدموية لدى مرضى الصدفية. قد يكون من المفيد للقيام الفحص المبكر والعلاج من مرض الصدفية في hyperlipidaemia لمنع تصلب الشرايين ومضاعفاتها.


Article
C-reactive protein and lipid profile among depot- medroxyprogesterone acetate injections users

Author: Wahda B. Al-Youzbaki وحدة بشير اليوزبكي
Journal: Annals of the College of Medicine Mosul مجلة طب الموصل ISSN: 00271446 23096217 Year: 2011 Volume: 37 Issue: 1&2 Pages: 48-56
Publisher: Mosul University جامعة الموصل

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Objective: To study the effect of depot-medroxyprogesterone acetate (DMPA) injections on C-reactive protein (CRP) and lipid profile and to find the predictors (body weight, body mass index (BMI), blood pressure (BP) and lipid profile) that significantly predict the risk of cardiovascular disease (CVD) among DMPA injections users.Method: A prospective cohort study was performed during the period from March 2009 to March 2010 included thirty apparently healthy married women, their age ranged between 20-35 years, who were attending Al-Batool and Al-Khansa Family Planning Centers in Mosul and started (for the first time) to use DMPA injections (150 mg medroxyprogesterone acetate), called "Depo-Provera" as contraceptive. These (DMPA users group) were compared to another 30 healthy married women who did not use any hormonal contraceptives (non users group). Both groups were followed for one year, during which blood samples were obtained from both groups, before starting to use DMPA, after 6 months and after 12 months. Sera were used for the estimation of the biochemical studied parameters using commercial kits except serum low density lipoprotein (LDL) and atherogenic index (AI) which were calculated by special equations. Results: DMPA injections caused a non significant increase in body weight but a significant increase in BMI after 12 months. There was a significant increase in the mean diastolic blood pressure (DBP) of DMPA users according to the duration of use. The DMPA caused non significant changes in the CRP levels. There was a significant increase in serum triglycerides (TG) after 6 months of DMPA uses with respect to the duration of use. But there were non significant changes in mean serum total cholesterol (TC), high density lipoprotein (HDL), LDL and AI. Among all variables that were studied, only body weight and BMI showed a significant positive correlations with CRP. Using a stepwise multiple regression analysis, it was found that the predictors that significantly predict the risk of CVD among DMPA users were AI, DBP and TG.Conclusion: This study found that there is a significant positive association between CRP and CVD risk factors in DMPA injections users as contraceptive. Furthermore AI, DBP and TG were found to be significant predictors for the risk of CVD among DMPA users. This study confirmed the safety of DMPA use as contraceptive medication, but that special care should be directed for patients with CVD and other patients who were more sensitive to the harmful effects of lipid in the blood.Key words: Depot-medroxyprogesterone acetate, CRP, lipid profile.

الهدف: لدراسة تأثير حقن مخزن ميدروكسي بروجيستيرون أسيتيت على البروتين التفاعلي نوع ج ودهون الدم وإيجاد المتنبآت (وزن الجسم، مؤشر كثافة الجسم، ضغط الدم ودهون الدم) التي تتنبأ معنويا بأمراض القلب الوعائية لدى مستعملات مخزن ميدروكسي بروجيستيرون أسيتيت. الطريقة: دراسة جماعة أجريت خلال الفترة من آذار 2009 إلى آذار 2010 تضمنت أخذ مجموع 30 امرأة سليمة (لمجموعة مستعملات (DMPA تتراوح أعمارهن بين (20 – 35) سنة مراجعات لمركزي تنظيم الأسرة في مستشفى البتول والخنساء في الموصل وممن بدأن لأول مرة بأستعمال حقن مخزن ميدروكسي بروجيستيرون أسيتيت والتي تسمى "Depo-Provera" (بتركيز 150 ملي غرام ميدروكسي بروجيستيرون أسيتيت) كمانع حمل كل ثلاثة أشهر وقد تم مقارنتهن مع 30 إمرأة سليمة أخرى (مجموعة الضبط) ممن لايستعملن موانع الحمل الهرمونية. كلتا المجموعتين تمت متابعتهن لمدة سنة واحده وخلالها تم سحب دم من كل إمرأة من كلا المجموعتين وعلى ثلاث فترات وهي قبل البدء بالمتابعة واستعمال حقن مخزن ميدروكسي بروجيستيرون أسيتيت وبعد 6 أشهر ثم بعد 12 شهرا. تم إستخدام عينات مصل الدم المأخوذة من نماذج الدم لقياس الفحوصات الكيمياوية المدروسة باستعمال العدد اليدوية التجارية ماعدا مؤشر كثافة الجسم، كوليسترول الدهن واطئ الكثافة في مصل الدم ومؤشر التصلب العصيدي باستعمال معادلات خاصة. النتائج: حقن مخزن ميدروكسي بروجيستيرون أسيتيت سببت زيادة غير معنوية بوزن الجسم ولكن زيادة معنوية بمؤشر كثافة الجسم بعد 12 شهر. كان هناك زيادة معنوية في ضغط الدم الواطئ لدى مجموعة مستعملات DMPAبالنسبة لمدة الأستعمال. إن حقن مخزن ميدروكسي بروجيستيرون أسيتيت سببت تغيرات غير معنوية في البروتين التفاعلي نوع ج في مصل الدم. كان هناك زيادة معنوية في مستوى ثلاثي الكليسيرايد في مصل الدم بعد 6 أشهر من استعمال حقن مخزن ميدروكسي بروجيستيرون أسيتيت وبالنسبة لمدة الإستعمال. بينما كان هناك تغيرات غير معنوية في معدل مستوى الكولسترول الكلي، كولسترول الدهن عالي الكثافة، كولسترول الدهن واطئ الكثافة ومؤشر التصلب العصيدي. بين كل المتغيرات المدروسة، فقط وزن الجسم ومؤشر كثافة الجسم أظهرا علاقة ايجابية معنوية مع البروتين التفاعلي نوع ج. بإستعمال التحليل التدريجي المتعدد الترددي وجد أن المتنبات ذات الدلالة والتي تتنبأ بخطورة حدوث أمراض القلب الوعائية لدى مستعملات حقن مخزن ميدروكسي بروجيستيرون كانت: مؤشر التصلب العصيدي، ضغط الدم الواطئ، ثلاثي الكليسيرايد. الاستنتاج: هذه الدراسة وجدت أن هناك مرافقة إيجابية ومعنوية بين البروتين التفاعلي نوع ج وعوامل الخطورة لأمراض القلب الوعائية بين مجموعة مستعملات DMPAكمانع للحمل. بالإضافة الى أن مؤشر التصلب العصيدي، ضغط الدم الواطئ وثلاثي الكليسيرايد قد وجدوا بأنهم من المتنبات المعنوية بخطورة أمراض القلب الوعائية لدى مستعملات DMPA. هذه الدراسة أكدت أمانة استخدام حقن مخزن ميدروكسي بروجيستيرون أسيتيت كموانع للحمل ولكن عناية خاصة يجب أن توجه لمرضى القلب الوعائية وغيرهم من المرضى الذين يكونون أكثر حساسية لتأثير أضرار الدهون في الدم. مفتاح الكلمات: مخزن ميدروكسي بروجيستيرون أسيتيت، البروتين التفاعلي نوع ج ودهون الدم.


Article
Effects of metformin on the lipid profllein polycystic ovarian syndrome patients
تاثير عقار المتفورمين على مستوى الدهون عند مرضى متلازمه تكيس المبايض

Authors: طارق ناصر موسى --- منال طه العبيدي --- قيس احمد ابراهيم
Journal: Iraqi Journal of Embryos and Infertility Researches المجلة العراقية لبحوث الأجنة والعقم ISSN: eISSN: 26166984 / pISSN: 22180265 Year: 2011 Volume: 1 Issue: 2 Pages: 13-17
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Polycystic ovary syndrome (PCOS) is (be most common and prevalent endocrinopathy in women , and the most common cause of anovulatory infertility- An altered lipid profile is common in polycystic ovary syndrome (PCOS) and is usually characterized by increased total cholesterol, triglycerides, low-density lipoproteins and very low density lipoprotein levels with low high-density lipoprotein. PCOS is associated wth a higher frequency of card Avascular disease because of dyslipidemia. Which are potent markers for cardiovascular risk factors. Metformin, is a widely used antihypenglycemic agent It decreases insulin resistance and reduces hyperglycemia through a reduction of the hepaticglucose production.ObjectivesDetermine Ihe beneficial effect of metformin in PCOS paliente in reducing lipid profile and subsequently reduction incardiovasculardisease.HctbodMeasurements and anaiysis levels of total cholesterol, triglycerides, taw-density lipoproteins, very low density lipoprotein and high-density lipoprotein were samples collected at the Institute of embryo research and infertility treatment. Al-Nahnain Univereity, PCOS patients were recruited at the consultant clinic Patients: forty three women with PCOS were studied. Anthropometric data, Jipki profile, were evaluated, before oral metformffi (50Qmg'twioedaify}treatinent and aflerthree months of use.Patients with PCOS after oral metformin treatment, revealed a sign ificant lowering serum concentrations of totat cholesterol, triglyceride, taw-density lipoproteins and very low density Apoprotein and elevated high- density lipoprotein compared to before treatment.cdqcbttkmsdyslipidemia is common finding in PCOS women, in this study we found that the use of oral metformin tablets 500mg/ twioe daily fcrthree months will correct lipid profile level (cholesterol triglyceride, LDL, VLDL and HDL) which is considered as caidiovascular risk factors and this lead to reduce risk of cardiovascular diseases.


Article
Serum lipid profile in patients with primary fibromyalgia

Authors: Enas J.Kaoud ايناس جاسم --- Munaf S.Daoud مناف صالح --- Mohammed H. Alosami محمد حسن
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2011 Volume: 53 Issue: 1 Pages: 89-92
Publisher: Baghdad University جامعة بغداد

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