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SOME OBSERVATIONS ON THE OCCURRENCE OF β-THALASSEMIA IN MOSUL

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Abstract

Backgroundβ-thalassemia is found in Mediterranean, Saudia Arabia, Jordan, Egypt and Yemen. Survey in Iraq showed that β-thalassemia trait is carried by 4.5-5% of the population.ObjectiveTo determine factors that is associated with thalassemia in Mosul district. Methods105 thalassemia blood transfusion dependent children with the age of 2.5–18 years attending Ibn Al-Atheer Teaching Hospital in Mosul city during 2005 were included in this study, 45 healthy subjects served as control. Blood groups, Hb, and PCV were evaluated. SI, TIBC, and TS levels were also determined.ResultsThe occurrence of homozygous β-thalassemia is significantly higher in the offspring of first cousin marriages."O" blood group represents a highest percentage (42.8%) among the thalassemic patients. Hb, PCV and TIBC were below the control measurements. Whereas SI and TS were above that of the controls.ConclusionsConsanguinity seems to be increasing the size of the disease due to the limited health education of the parents about the disease.Key wordsThalassemia, Hb, PCV, SI, TIBC, TS

Keywords

Thalassemia --- Hb --- PCV --- SI --- TIBC --- TS


Article
The influence of Packed Cells Volume (PCV) and Temperature on Erythrocytes Sedimentation Rate (ESR)
تأثير حجم كريات الدم المضغوطة و درجة الحرارة في معدل ترسيب كريات الدم الحمر

Author: Suha Adel Qasim سها عادل قاسم
Journal: Baghdad Science Journal مجلة بغداد للعلوم ISSN: 20788665 24117986 Year: 2011 Volume: 8 Issue: 1 Pages: 118-122
Publisher: Baghdad University جامعة بغداد

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Abstract

Erythrocytes aggregation is an important physiological phenomenon in the circulation of blood, and is a basic characteristic of normal blood that plays a major role in cardiovascular system especially in the microcirculation.Blood samples have been taken from (30) volunteers (15 male, and 15 female), their ages (20-30) years. The Erythrocytes Sedimentation Rate (ESR) for those subjects was measured at different Packed Cells Volume (PCV) (10%-25%), and also it was measured at different temperature (10oC-25oC).The results show that there was a highly significant decrease (P<0.01) in ESR when the PCV increase and a highly significant increase (P<0.01) in ESR when the temperatures increase.The conclusion from these results is that the ESR values were affected by each of PCV and temperature of the samples.

تجمع كريات الدم الحمر هي ظاهرة فيزيولوجية في الدورة الدموية وهي خاصية أساسية في الدم الطبيعي تؤدي دوراً كبيراً في الدورة الدموية وخاصة في الأوعية الدموية الشعرية.تم أخذ عينة دم من (30) شخصاً (15 ذكراً و 15 انثى) وبأعمار (20-30) سنة، أذ تم حساب معدل ترسيب كريات الدم الحمر لمختلف قيم حجوم الكريات المضغوطة (10%-25%)، وكذلك تم حساب معدل ترسيب كريات الدم الحمر في مختلف درجات الحرارة (10مo-25مo).أظهرت النتائج أن هناك نقصاناً ملحوظاً ذا معنوية عالية (P<0.01) في معدل ترسيب كريات الدم الحمر عند زيادة حجوم الكريات المضغوطة وكذلك أظهرت النتائج أن هناك زيادة ملحوظة ذات معنوية عالية (P<0.01) في معدل ترسيب كريات الدم الحمر عند زيادة درجة الحرارة.نستنتج من ذلك أن معدل ترسيب كريات الدم الحمر يتغير بتغير كل من حجوم الكريات المضغوطة و درجة حرارة العينات.

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