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Article
Superficial Fungal infections

Authors: Auroba K. Abbas --- Zahraa A. Mohammed --- Imad S. Mahmoud
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2012 Volume: 11 Issue: 1 Pages: 75-77
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: This work aimed to isolate and identify fungi from different superficial fungal infection since these infections are widely distributed among low socioeconomic level people.Patients and Methods: All clinical specimens from skin, hair, scalp and feet were diagnosed as dermatophytes or other fungi according to well-known established mycological methods for isolation and identification of certain fungi. Results: This study was undertaken at AL-Yarmook Teaching Hospital during the period January 2008-December 2009 in which 55 clinically diagnosed as fungal infection were the source of clinical specimens. Out of 55 cases it has been found that 45 specimens (81.8%) were positive for fungi from which 21 (46.6%) were dermatophytes, 16 (35.5%) pityriases versicolor, 8(18.2%) candida albicans.Conclusion: It is concluded that dermatophytes are the major cause of mycotic superficial infections and that skin is the predominant area of the body which is invaded by fungi.


Article
In vitro,study of Senna alata leaf extract against Dermatophytes
دراسة فعالية مستخلص اوراق نبات السنامكي Senna alata ضد الفطريات الجلدية، مختبريا

Author: عادل عدنان علي
Journal: journal of the college of basic education مجلة كلية التربية الاساسية ISSN: 18157467(print) 27068536(online) Year: 2012 Volume: 18 Issue: 75 Pages: 743-754
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

This study was conducted to investigate the in vitro antifungal activity of Senna alata leaf extract on the skin fungi (dermatophytes). The studies on the in vitro investigation of antifungal activity of ethanolic extract of Senna alata L. leaf was carried out. The test was conducted on dermatophytes which included the genera of Trichophyton, Microsporum and Epidermophyton. These fungi are the causative agents of various types of fungal skin diseases (dermatophytosis) which attack various parts of the body and tend to the following conditions, Tinea capitis, Tinea cruris, Tinea corporis and Tinea pedis. The results obtained showed that the leaf ethanol extract of Senna alata had marked antifungal effects on Microsporum canis, Trichophyton rubrum, T. mentagrophytes and Epidermophyton fluccosum. The ethanolic extract showed the highest inhibition on Trichophyton rubrum and Epidermophyton fluccosum with 20.50 and 20.00 mm zone of inhibition, respectively. The Minimum Inhibitory Concentration (MIC) was also performed and the results showed that the MIC of Senna alata on all the tested dermatophytes was 5.0 mg/ml.

تم دراسة فعالية مستخلص اوراق نبات السنامكي Senna alata ضد الفطريات الجلدية dermatophytes مختبريا، وقد تم تقييم كفاءة المستخلص الكحولي باستخدام الكحول الاثيلي ethanolic extract للاوراق ضد الفطريات الجلدية التابعة للاجناس Trichophyton ، Microsporum و Epidermophyton والتي تسبب انواعا مختلفة من الامراض الجلدية dermatophytosis التي تصيب الاجزاء المختلفة من الجسم وتشمل قوباء الرأس Tinea capitis، القوباء الوركية Tinea cruris ، قوباء الجسم Tinea corporis وقوباء القدم Tinea pedis.لقد بينت نتائج هذه الدراسة بأن مستخلص اوراق نبات السنامكي لها تأثير قوي كمضاد فطري antifungal ضد كل من الفطريات Microsporum canis ، Trichophyton rubrum ، T. mentagrophytes و Epidermophyton fluccosum . ان المستخلص الكحولي باستخدام الايثانول قد اظهر اعلى درجة تثبيط في الفطر T. rubrum والفطر E. fluccosum بمنطقة تثبيط 20.50 و 20.00 ملم، على التوالي. تم حساب التركيز المثبط الادنى (MIC) وقد اظهرت النتائج بان التركيز المثبط الادنى لمستخلص اوراق السنامكي لجميع الفطريات الجلدية المدروسة كان 5.0 ملغم/مل.

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