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Article
A Biochemical Study for Evaluation and Analysis of Serum Protein of Patients with Different Kidney Tumors
دراسة كيموحيوية لتقييم وتحليل البروتينات المصلية لدى مرضى الأورام الكلوية المختلفة

Authors: Majid Kadhum Husain ماجد كاظم حسين --- Hathama Razoki Hasan حذامة رزوقي حسن --- Rasha Hassan Jsiem رشا حسن جاسم
Journal: Baghdad Science Journal مجلة بغداد للعلوم ISSN: 20788665 24117986 Year: 2012 Volume: 9 Issue: 2 Pages: 311-321
Publisher: Baghdad University جامعة بغداد

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Abstract

The amount of protein in the serum depends on the balance between the rate of its synthesis, and that of its catabolism or loss. Abnormal metabolism may result from nutritional deficiency, enzyme deficiency, abnormal secretion of hormones, or the actions of drugs and toxins. Renal cancer is the third most common malignancy of the genitourinary system, and accounts for 3% of adult malignancies globally. Total serum proteins were measured in malignant kidney tumor, benign kidney tumors, and non tumoral kidney diseases patient groups, as well as in healthy individuals. A significant decrease (p< 0.001) of total serum protein levels in patients with malignant kidney tumors when compared with those of benign tumors, non tumoral diseases, and healthy individuals. The lowest serum protein levels were found in patients with stage IV, regardless their genders. Analysis of total serum proteins using PAGE revealed clear differences in the number and shape of the bands in patients with different kidney diseases compared with healthy controls.

كمية البروتين في المصل تعتمد التوازن بين نسبة التخليق ومقدار ما يؤيض منه هدمياً. الايض غير الطبيعي للبروتين قد يكون ناجماً عن نقص التغذية أو نقصاً إنزيميا أو عن افرازغير طبيعي للهرمونات أو نتيجة لفعل دوائي أو سمي. سرطان الكلية هو ثالث سرطانات الجهاز البولي شيوعاً ويشكل 3% من مجمل حالات السرطان. تم قياس مستويات البروتين الكلي في أمصال مرضى الأورام الكلوية الخبيثة منها والحميدة ومرضى الاعتلالات الكلوية غير الورمية وكذلك لدى الأفراد الأصحاء، وقد لوحظ انخفاض معنوياً(p < 0.001) في مستوى البروتينات المصلية عند مرضى الأورام الكلوية الخبيثة مقارنة مع أفراد باقي المجاميع، وقد سجلت أوطأ مستوياته عند مرضى المرحلة الرابعة من الورم بغض النظر عن جنس المريض.تحليل البروتينات الكلية باستخدام تقنية الترحيل الكهربائي على هلام الاكريل امايد لأمصال مجاميع الدراسة اظهر اختلافاً واضحاً في أعداد وأشكال الحزم عند مرضى الاعتلالات الكلوية مقارنة مع الأفراد الأصحاء.

Keywords

Serum proteins --- Kidney --- Tumors


Article
THE SERUM COPPER AND ZINC VALUES OF THE SHEEP GROWN UP IN THI_QAR VILLAGES
قياس القيم المصلية للنحاس والزنك للأغنام التي تربى في قرى محافظة ذي قار

Author: Sheren Ali , Jalel abed شيرين علي حسن ,.جليل عبد غباط
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2012 Volume: 11 Issue: 1 Pages: 265-269
Publisher: Basrah University جامعة البصرة

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Abstract

he present study was planned to determine serum Micro mineral status (copper and zinc) of the sheep grown up in Thi_Qar villages .The serum copper &zinc values of the animals were analyzed .with atomic absorption spectrophotometer . The result showed there were non significant differences in all mean serum values of sheep except the mean serum values for animal which showed clinical sings were decrease significantly when compared with other animal which whereby not shown clinical sings .

تهدف الدراسة الحالية إلى تحديد قيم معدلات المصل للنحاس والزنك في ألأغنام التي تربى في قرى محافظة ذي قار ,تم تحليل عينات المصل للزنك والنحاس في جهازالمطياف الضوئي للأمتصاص الذاتي وحيث بينت النتائج بأنه لا توجد أختلاف معنوي في معدل القيم المصلية للنحاس والزنك لمعظم للأغنام ماعدا تلك التي أظهرت عليها بعض العلامات السريرية حيث كانت معدل قيمها المصلية أقل معنويآ .

Keywords

Copper --- Serum --- Sheep


Article
USING SORGHUM (SORGHUM BICOLOR L.) AND PEAS (PISUM SATIVUM) AS REPLACEMENT FOR YELLOW CORN AND SOY BEAN AND THEIR EFFECTS ON GROWTH , HEMATOLOGY AND SERUM BIOCHEMICAL PARAMETERS OF BROILER CHICKS
استخدام الذرة البيضاء والبازلاء كبدائل عن الذرة الصفزاء وفول الصويا وتأثيرها على النمو والمعايير الدموية والبايوكيميائية المصلية في فروج اللحم

Author: Nawras A. Alwan نورس عبد الاله علوان
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2012 Volume: 11 Issue: 1 Pages: 293-306
Publisher: Basrah University جامعة البصرة

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Abstract

This work was done to investigate the effect of replacing the yellow corn (maize) with sorghum (white corn) and soy bean with peas on body weight, food intake, some hematological (PCV. And Hb) and also on some biochemical parameters (protein and urea). 72 one day old unsexed broiler chicks of average body weight 40-45 gm; they were divided into 3 equal groups of 24 chicks with 3 replicates. The first group were fed a diet containing sorghum ; the second group were fed a diet containing peas while third group fed normal diet. All groups fed on a starter diet for the first 28 days and then fed on growth diet till 49 days of age. Results showed significant increase in food intake, body weight in all experimental groups. Also significant increase were obtained in hematological parameters increased (Hb and PCV)as well as in serum biochemical parameters studied (P<0.05)for protein and urea in first and second groups compared to control group (Group 3).

Keywords

yellow corn --- sorghum --- serum


Article
Zinc Status In Children With Bronchial Asthma

Authors: Tiran Abdulsttar Kakarash --- Abbas Al-Rabaty
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2012 Volume: 11 Issue: supplement Pages: 698-703
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT: BACKGROUND: Bronchial asthma is a chronic inflammatory disease of the respiratory tract. The rise in asthma and allergic disease among children is a matter of worldwide concern. Many authors have argued that the changes in diet may have been an important determinant of increased susceptibility to asthma. Free radicals have been proposed to be responsible for the pathogenesis of many diseases because of their harmful effects on the cells and tissues. The enzymes responsible for antioxidant defense have trace elements like zinc. OBJECTIVE: To evaluate the relation between bronchial asthma and zinc serum level, and the relation between serum zinc level and the duration and severity of asthma. PATIENTS AND METHODS: A Case control study was conducted at Raparin pediatric teaching hospital in Erbil city. Fifty children from ages 1 to 12 years of both sexes who were known cases of asthma and had visited Raparin teaching hospital were enrolled in this study, another sample of 50 healthy children matched for age and gender, without history of chronic disease were taken as a control group. The zinc concentrations in serum were measured in both cases and controls. RESULTS: This study shows that there were significant difference in the values of serum zinc between asthmatic and control group (p<0,01 and p<0,01 respectively).The mean concentrations of zinc are lower in asthmatic children(70.02μg/dl) in comparison to controls(84.04μg/dl).CONCLUSION: Children with bronchial asthma have a great risk of zinc deficiency, and serum zinc level has significant relation to the severity of asthma and the use of steroid

Keywords

asthma --- serum zinc


Article
Study of the effect of hyperthyroidism on the serum cholesterol and albumin level in women in Najaf
دراسة تأثير زيادة إفراز الغدة الدرقية على مستوى الكولسترول والألبومين في مصل النساء في محافظة النجف

Author: Sheymaa G. shamran Al-jafery
Journal: kufa Journal for Nursing sciences مجلة الكوفة لعلوم التمريض ISSN: 22234055 Year: 2012 Volume: 2 Issue: 2 Pages: 142-146
Publisher: University of Kufa جامعة الكوفة

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Abstract

Abstract:Objectives: to study the impact of increased thyroid secretion on levels of serum cholesterol and albumin in serum women.Methodology: a study in applied AL-Sader educational hospital for the period from March 2011 to August 2011 including the study the measuring of concentration of cholesterol and albumin in serum blood of (53) women patients of hyperthyroidism. The researcher used statistical analysis of data.Results: the search results showed significant decrease in the rate of albumin concentration compared to control group (p < 0.001). And a decrease in cholesterol concentration compared with the control group (p < 0.001).Recommendations: the study recommends compensation decrease blood cholesterol and with increased thyroid secretion by addressing the complementary and healthy food appropriate for each situation.

الخلاصة:الأهداف : لمعرفة تأثير زيادة إفراز الغدة الدرقية على مستويات الكولسترول والألبومين في مصل النساء.منهجية البحث : أجريت دراسة تطبيقية في مستشفى الصدر التعليمي للفترة من آذار 2011 إلى آب 2011 حيث شملت الدراسة قياس تركيز الألبومين والكولسترول في مصل دم(53) من النساء المريضات بمرض فرط الغدة الدرقية. واستخدم الباحث التحليل الإحصائي للبيانات المأخوذة.النتائج :أظهرت نتائج البحث نقصان معنوي في معدل ألألبومين مقارنة مع مجموعة السيطرة (p<0.001). ونقصان معنوي في معدل الكولسترول مقارنة مع مجموعة السيطرة(p<0.001) .التوصيات : توصي الدراسة بتعويض نقصان الألبومين والكولسترول في الدم ممن لديهم زيادة إفراز الغدة الدرقية بتناول المتممات الغذائية والغذاء الصحي المناسب لكل حالة.


Article
Serum zinc in psoriatic patients

Author: Adnan Abd Oun Hashim Al-Jebory
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2012 Volume: 11 Issue: 2 Pages: 20-23
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: Psoriasis is a common skin disorder affecting 1% to 3% of thepopulation all over the world. Many etiological factors have beenimplicated but trace elements, especially zinc, may play an importantrole.Aims: This study was done to evaluate the serum level of zinc in patientswith psoriasis and it's relation to clinical types, duration and surface areaof the disease.Patients and Methods: Fifty patients (25 males & 25 females) withdifferent ages and different types of psoriasis were chosen for thisstudy. Also 50 non-psoriatic volunteers, sex and age matched wereserved as controls, evaluated for serum zinc level.Results: The result of this study has shown that 49 (98%) of psoriaticpatients have low serum zinc compared with 2 (4 %) among controls(P=0.0001). The type of psoriasis may have an effect on serum zinc, thelowest mean serum zinc is found in palmo-planter (plaque) psoriasis (14%of patients) (P=0.025).Conclusions: From this study we can conclude that zinc deficiency mayplay a role in psoriasis since most patients (98%) have low serum level.


Article
Evaluation the Levels of Serum Hormones (Progesterone, Estradiol, and hCG) in Preeclamptic IraqiPregnancies
تقييم مستوى الهرمونات في مصل النساء العراقيات ذوات مقدمة الارتعاج

Authors: Amna N.Jassim آمنة نصيف جاسم --- Abbass M. Rahmah عباس مهدي رحمة --- Suaad A. Brakhas سعاد الماس براخاس
Journal: Baghdad Science Journal مجلة بغداد للعلوم ISSN: 20788665 24117986 Year: 2012 Volume: 9 Issue: 2 Pages: 244-250
Publisher: Baghdad University جامعة بغداد

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Abstract

This study aimed to evaluate serum levels of steroid hormones and human chorionic gonadotropin (hCG) hormone in preeclamptic Iraqi pregnancies compared to those of healthy pregnancies.This study enrolled 120 pregnant women, divided into four groups:1.30 healthy pregnant women.2.37 pregnant women with mild preeclampsia3.53 pregnant women with severe preeclampsia4.90 pregnant women with preeclampsia Preeclamptic women and their severe cases but not mild cases had significantly (P<0.01) increased levels of serum hCG as compared with healthy pregnancies. By contrast, sera levels of estradiol were significantly (P<0.01) decreased in total preeclamptic groups and their severe cases but not in mild group as compared to healthy pregnant women (controls) , while there were no significant differences in the levels of serum progesterone in all preeclamptic groups as compared with controls.This study that concludes Preeclampsia is associated with increased levels of hCG hormone and decreased levels of estradiol hormone and these support the suggestion of the role of hormones in preeclampsia.

تضمنت هذه الدراسة تقييم مستويات كل من الهرمونات الستيرويدية البروجستيرون والاستراديل وهرمون hCG في امصال النساء العراقيات المصابات بمقدمة الارتعاج (تسمم الحمل), شملت هذه الدراسة 120 امراة حامل قسمت الى اربعة مجاميع:المجموعة الاولى : مجموعة النساء السليمات كسيطرة (30) المجموعة الثانية : مجموعة النساء ذوات مقدمة الارتعاج المعتدل (37) المجموعة الثالثة : مجموعة النساء ذوات مقدمة الارتعاج الشديد (53) المجموعة الرابعة : مجموعة النساء ذوات مقدمة الارتعاج الكلي (90) اظهرت نتائج الدراسة الحالية ارتفاع معنوي (P<0.01) في مستوى هرمون hCG في امصال النساء ذوات مقدمة الارتعاج الحالات الشديدة منها مقارنة بالحالات المعتدلة ومجموعة السيطرة وكذلك انخفضت معنويا (P<0.01) مستوى هرمون الاستراديول في امصال النساء ذوات مقدمة الارتعاج وخاصة الحالات الشديدة مقارنة بالحالات المعتدلة ومجموعة السيطرة , في حين لم يكن هنالك اي فرق معنوي في مستوى هرمون البروجستيرون في كافة مجامي المرضى ومجموعة السيطرة .نستنتج من هذه الدراسة ان مقدمة الارتعاج له علاقة بزيادة مستويات هرمونت hCG وانخفاض في مستويات هرمون estradiol وهذه تساند الاقتراح في دور الهرمونات في مقدمة الارتعاج (preeclampsia).


Article
Inhibitory Effect Of Oxadiazooles And Thiadiazoles In Vitro On Serum Alkaline Phosphatase Enzyme Of Pregnant Woman

Authors: Tawfeeq F. R. AL-Auqbi توفيق العقابي --- Noor tha'ir Tahir Al-Khalidi نور ثائر الخالدي
Journal: Al-Mustansiriyah Journal for Pharmaceutical Sciences مجلة المستنصرية للعلوم الصيدلانية ISSN: 18150993 Year: 2012 Volume: 11 Issue: 1 Pages: 1-8
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Abstract:To assess the inhibitory effect of oxadiazole and thiadiazole derivativeson serum alkaline phosphatase level of pregnant in vitro. A cross-sectional studyon 34 pregnant women was carried out at Al-Kadhumia Teaching Hospital. The mechanism of Inhibitory effect of Oxadiazoles and Thiadiazoles derivatives in vitro on alkaline phosphatase enzyme of pregnant women due to thedephosphorylation reaction which block the ALP activity.Key Words: Oxadiazoles, Thiadiazoles, serum alkaline phosphatase

الخلاصة:لغرض تقییم التأثیر المثبط لمركبات الأوكسیدیازول والثیادیازول على مستویات أنزیم الفوسفیتیزالقاعدي في مصل الدم للنساء الحوامل مختبریا. صممت الدراسه بشكل دراسه مقطعیه على 34 امرأهحامل في مستشفى ألكاظمیه التعلیمي. تبین من الدراسه ان آلیه التثبیط لمركبات الاوكسادیازولوالثیادیازول لأنزیم الفوسفتیز القاعدي مختبریا تحدث نتیجة لتفاعل أزاله الفسفره والتي تعیق فعالیه أنزیمالفوسفتیز القاعدي.


Article
Quantitative analysis of IgG antinuclear antibody in chronic periodontitis patients

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Abstract

Background: Periodontitis is a bacterial infection of tooth-supporting tissues; the immunopathologic mechanismsinclude inflammatory cells and chemical mediators, which persist inflammation and develop a local autoimmune.The presence of autoantibodies against extracellular matrix components, anti-neutrophil cytoplasmic antibodies(ANCA) and anti-DNA was detected. This study aimed to provide evidence of altered humoral immune response inchronic periodontitis, as well as to determine the presence of auto-antibodies in this disease.Subjects and Methods: Blood samples were collected from 35 patients with chronic periodontitis (20 with severperiodontitis and 15 with moderate periodontitis) and from 30 healthy age and sex matched individuals served ascontrols. Clinical periodontal parameters used in this study were plaque index, gingival index, probing pocket depth,clinical attachment level and bleeding on probing. The levels of serum IgG-antinuclear antibody were determinedusing enzyme-linked immunosorbent assays, whereas serum immunoglobulin (IgG, IgM and IgA) were estimated bysingle radial immune diffusion method.Results: Serum levels of IgG-antinuclear antibody and IgG were significantly higher in sever chronic periodontitis thanin moderate chronic periodontitis and healthy controls (p<0.05). On the other hand, the serum levels of IgM and IgAshowed no significant differences among three studied groups (p>0.05). Concerning the correlation between serumIgG-antinuclear antibody and clinical periodontal parameters, the level of this autoantibody did not show anycorrelation with clinical parameters of periodontitis (p>0.05).Conclusion: The production of antibodies against self structures could be involved in the pathogenic mechanism ofchronic periodontitis


Article
Changes in Body Weight, Serum (Sodium, Potas-sium) and Serum Albumin after Intermaxillary Fixation in Traumatized and Obese Patients (Comparative Study)

Authors: Wael Sheet --- Mohmmed K. Hassouni
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2012 Volume: 12 Issue: 1 Pages: 52-56
Publisher: Mosul University جامعة الموصل

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Abstract

Aims of the study: to evaluate the effects of intermaxillary fixation (IMF) on body weight, serum electrolytes ( Na+ and K+ ) and serum Albumin in traumatized and obese patients and to compare the changes between these two groups. Materials and Methods: A non randomized prospective study was done. The anthropometric measurement included 4 sites of skin fold thickness (triceps, biceps, subsca-pular and suprailiac skin folds), upper arm circumference, body mass index and laboratory investiga-tions to assess serum(Na+ and K+) levels and serum albumin level. The patients were divided in to 2 groups, the first group included 25 traumatized patients and the second group included 7 volunteer ob-ese patients and IMF was placed for those patients as one of the treatment lines for their body weight reduction and were considered as the control group. The parameters were recorded for each patient in the 2 groups preoperatively, one week, three weeks and six weeks postoperatively. Paired and un paired T tests were used in the statistical analysis, a P value < 0.05 was considered highly significant. Results: The changes of the anthropometric measurements, body mass index, serum K+ and serum albumin were statistically highly significant in traumatized patients with body weight loss ranging be-tween (5-8) Kg in this group. The changes of the anthropometric measurements and body mass index in the obese patients group were also statistically highly significant with a loss of (5-6) Kg in body weight in this group. The changes of anthropometric measurements and body mass index were statisti-cally highly significant in traumatized patients than in obese patients, while the changes in serum (Na+ and K+ ) and serum Albumin level were statistically not significant between the two groups. Conclu-sion: IMF compromises the nutritional status of the patients leading to loss of water, fat and protein in both traumatized and obese patients but the effect more pronounced in traumatized patient due to the metabolic and hormonal response to trauma together with the limited oral intake.

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