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Delay Neurological Development in Two Children with Megaloblastic Anemia

Authors: Abbas A. Alrabaty --- Azhar H.ALsaqy
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2013 Volume: 12 Issue: 2 Pages: 312-314
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

Vitamin B12 deficiency in infants often produceshaematological and neurological deficits, includingmacrocytic anaemia ,neurodevelopmental delay orregression, irritability, weakness ,hypotonia ,ataxia, apathy, tremor, and seizures. The diagnosisof vitamin B12 deficiency can be difficult whenthe typical macrocytic anaemia is absent) Infantile vitamin B-12 deficiency with ineffectivehaematopoiesis and degeneration of nervous tissuehas been reported in breast fed infants of motherson strict vegetarian diets 2) ) Adults may toleratevitamin B-12 deficient diets for many yearswithout apparent symptoms due to theirendogenous stores. In contrast, infants have verylimited hepatic reserves of vitamin B-12 and somay develop symptoms of deficiency withinmonth's2) (. we report two cases in which they werediagnosed as cerebral palsy in early life. first casewas 9 month old female baby presented withpallor for last 3 months of age, floppiness ,regressof acquired millstone ,exclusive breast feed for avegan mother ,diagnosed as megaloblastic anemiasecond case was 16 months old male babypresented with apathiness , he was exclusivelybreast feed till this age with minimumcomplementary food.KEY WORDS : megloblstic anemia ,breast feed

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