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Article
Lipid Profile in Children with Chronic Renal Failure Undergoing Hemodialysis

Author: Qahtan M. Ali, Nariman F. Ahmed Azat
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2015 Volume: 14 Issue: 2 Pages: 222-228
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT: BACKGROUND: Dyslipidemia is common in Patients with chronic renal failure undergoing intermittent haemodialysis and is considered a risk factor of cardiovascular disease in these patients. OBJECTIVE: To highlight the lipid profile abnormalities in children with end stage renal disease undergoing maintenance hemodialysis and know whether the hemodialysis duration and frequency of sessions per week has any impact on lipid profile in these patients. PATIENTS AND METHOD: A case-control study which was collected in the dialysis unit of (Al Karama Teaching Hospital, Child's Central Teaching Hospital , Al Kadhumia Teaching Hospital and Ibn Al Balady Hospital) for six months started on 1st June 2013 till the 1st of December 2013. Blood samples were obtained from 40 patients with end stage renal disease undergoing maintenance haemodialysis (2-3 sessions per week) and 40 matched healthy controls and analyzed for serum total cholesterol, low density lipoproteins, high density lipoprotein and serum triglyceride. RESULTS: A statistically significant decrease was found in serum high density lipoprotein level (Mean= 46.40mg/dl ,p < 0.025) in Hemodialysis patients when compared with healthy controls. A significant increase in serum triglyceride content of patients (p < 0.000) was also observed. It was found that improvements in lipid profile results were achieved with the use of more frequent (more than 2sessions of haemodialysis per week). There is no any impact of the duration being on HD on the lipid profile in the study.CONCLUSION: This study found that normal lipid profile is better maintained in patients undergoing adequate haemodialysis, and the frequency of haemodialysis sessions can affect the atherogenic states of the lipid profile which is probably the responsible for high incidence of atherosclerotic heart diseases among these patients.


Article
Salivary IgA in chronic kidney disease patients undergoing hemodialysis in Missan governorate

Authors: Faris Abid Hatem فارس عبد حاتم --- Zaheda Jassim Mohammad زاهدة جاسم محمد
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2015 Volume: 27 Issue: 2 Pages: 54-57
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Chronic kidney disease is a worldwide health problem, with adverse outcomes of cardiovasculardisease and premature death, can be divided into five stages, depending on how severe the damage is to thekidneys, or the level of decrease in kidney function, the final stage of chronic kidney disease is called end-stagerenal disease, salivary immunoglobulin A is the main immunoglobulin found in mucous secretions, including tears,saliva, colostrum and secretions from the genitourinary tract gastrointestinal tract, prostate and respiratoryepithelium. It is also found in small amounts in blood.This study aimedto measuresalivary flow rate andsalivaryimmunoglobulin Alevels in chronic kidney disease patients on hemodialysis treatment in comparison withhealthy control subjects.Materials and Methods: Ninety (90) subjects were participated in this study; 45 Patients undergoing hemodialysis withchronic kidney diseases; 45 health control subjects. Saliva collected was measured and levels of salivaryimmunoglobulin A were measured by Enzyme Link Immunosorbent Assay (Elisa).Results:The present studyrevealed that the mean value of salivary flow rate in chronic kidney disease patients was(0.34 ± 0.19) ml/min, while for healthy control subjects was (1.02 ± 0.39) ml/min, there wasstatisticallysignificantlydecrease in salivary flow rate ofchronic kidney disease on hemodialysis patients as compared to control healthysubjects.The present study revealed that the (Mean±SD) of the immunoglobulin A in chronic kidney disease patientson hemodialysis (388.81±227.86) μg./ml, while in control group (273.98±155.89) μg./ml, the result revealed statisticallysignificant increase in chronic kidney disease patients on hemodialysis as compared to control subjects.Conclusions: Salivary immunoglobulin (IgA) reflects the functional capacity of the glands. Increased concentrationof this component is usually marker of a poor general condition

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