research centers


Search results: Found 25

Listing 1 - 10 of 25 << page
of 3
>>
Sort by

Article
Determination of Serum CA125 and evaluate its efficiency as screening tool For Early Detection of Ovarian Tumors
تحديد المستوى المصلي للمستضد السرطاني 125 وتقييم كفاءته كوسيلة فحص للتشخيص المبكر لأورام المبيض

Authors: Munther J. Hussein منذر جعفر حسين --- Maisaa G. Jumaa ميساء غازي جمعة --- Khalid A. Habib خالد عبد الرزاق حبيب
Journal: Baghdad Science Journal مجلة بغداد للعلوم ISSN: 20788665 24117986 Year: 2015 Volume: 12 Issue: 1 Pages: 55-62
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Epithelial ovarian cancer is the leading cause of cancer deaths in women. To date, an effective screening tool for ovarian cancer has not been identified Several clinical and biological factors including serum cancer antigen 125 (CA- 125) have been assessed for prognostic and predictive relevance CA-125 is an epithelial marker derived from coelomic epithelium. It is elevated in 90% of advanced ovarian cancers and in 50% of early ovarian cancers while 20% of ovarian cancers have low or no expression of CA- 125 CA-125 concentrations were measured by Mini Vidas test (VIDAS CA125 II / BIOMERIEUX / France). The median CA-125 levels were significantly higher in the sera of ovarian cancer patients than in those with benign tumors and in healthy controls. However in correlation with stages the results showed that Patients with stage II have highly significant differences in level of serum CA125 compare with stage I in and stage III.CA125 showed low sensitivity to detect stage I carcinoma of the ovary which limits its value as an initial screening tool therefore combining of CA125 with other markers might enable improved early detection of ovarian cancer as compared with use of this marker alone.

يعتبر سرطان المبيض الطلائي احد المسببات المؤدية الى الموت من بين الامراض النسائية.الى هذا التاريخ لم يتم تشخيص وسيلة فحص فعالة للكشف عن سرطان المبيض. العديد من العوامل السريرية و البايلوجية ومنها الانتجين السرطاني 125 تم تقييمها من حيث علاقتها بالمرض وتقدمه. الانتجين السرطاني 125 هو معلم طلائي مستمد من التجويف الطلائي وهو يرتفع في حوالي 90% من حالات سرطان المبيض المتقدمة وفقط 50% من حالات سرطان المبيض المبكر في حين 20% من هذه الحالات لا تظهر او تظهر تعبير منخفض لهذا الانتيجين السرطاني. تم قياس تراكيز للانتجين السرطاني 125 باستخدام اختبار MiniVidas test. وقد اظهرت النتائج ان متوسط تركيز للانتجين السرطاني 125 قد اظهر فروقات عالية المعنوية في مصول المريضات المصابات بسرطان المبيض عند المقارنة مع تلك الماخوذة من المريضات المصابات بأورام المبيض الحميدة ومجموعة السيطرة.لكن عند المقارنة مع مراحل الورم اظهرت النتائج ان عينات المرضى في المرحلة الثانية قد اظهروا فروقات عالية المعنوية عند المقارنة مع مرضى المرحلتين الاولى والثالثة. ان الانتجين السرطاني 125 يعتبر واطئ الحساسية في تشخيص المرحلة السرطانية الاولى للمبيض مما يحدد قيمته كوسيلة اولية للفحص لذلك فان ارفاق الانتجين السرطاني 125 بمعلمات اخرى قد يساهم في تحسن عملية التشخيص المبكر لسرطان المبيض بالمقارنة مع استخدامه بشكل مفرد.

Keywords

Ovarian cancer --- CA125 --- Serum


Article
Assessment of serum ferritin levels in thalassemia and non-thalassemia patients presented with anemia

Authors: Mohammed Mahdi Abdulomohsin AL-Zubaidi --- Khiaria Jaber Tutli Alkhtaua
Journal: Iraq Joural of Hematology المجلة العراقية لامراض الدم ISSN: 20728069/25432702 Year: 2015 Volume: 4 Issue: 1 Pages: 119-125
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

ABSTRACTBackground: Thalassemia is an autosomal genetic disease leading to anemia and remains one ofthe major health problems in Southeast Asia and other parts of the world. Almost 100,000 patientswith major thalassemia need regular transfusion. Human hemoglobin (Hb) is the molecule thatcarries and transports oxygen all through the body. Ferritin is the principal iron storage protein,found in the liver, spleen, bone marrow, and to a small extent in the blood.Objectives: The aim of this study was to assess serum ferritin levels in B-thalassemia patients,and to compare it with non-thalassemic anemia and healthy control.Materials and methods: A prospective cross sectional study conducted at Thalassemia Center inIbn Al- Baladi Hospital for Children and Women during the period from1st February to 30th May2014 during their attendance to out-patient clinic. A total .number of 101 patients complaining ofanemia (51 patients with thalassemia, 50 with non-thalassemia) in addition to 50 healthy subjectsconsidered as control. All patients were tested for Serum ferritin levels and all results wereobtained through automated quantitative test for use Vidas machineResults : The mean serum ferritin levels in cases of thalassemia was 9542 + 782 ng/ml whileserum ferritin levels in control sample was 138 +323 ng/ml in male and 28+ 108 ng/ml in female .in patients with non-thalassemia anemia, the levels of serum ferritin was 1+80 ng/ml. Age of allpatients in this study ranged from 3day-9year .the age of thalassemia patients ranged from 1-6year and p-value was(0.23) while the age of patients with non-thalassemia anemia was 1-5 yearand p-value was (0.11).Conclusion: This study confirm that serum ferritin is high in patients wih thalassemia than nonthalassemia.


Article
Inhibition Effect of Noble Metals Nanoparticles on Acid Phosphate Activity in Sera of Healthy Subject
دراسة تثبيط جسيمات المعادن النانوية النبيلة على انزيم ACP في المصل لعينات سليمة

Authors: Eaman A.S.AL-Rubaee --- Abdulrahman K Ali --- Amenah Ali Salman --- Zainab A.Salman
Journal: Engineering and Technology Journal مجلة الهندسة والتكنولوجيا ISSN: 16816900 24120758 Year: 2015 Volume: 33 Issue: 1 Part (B) Scientific Pages: 1-11
Publisher: University of Technology الجامعة التكنولوجية

Loading...
Loading...
Abstract

Noble metals nanoparticles prepared by laser ablation in water. The structural and optical properties of the Ag and Au nanoparticles investigated using (UV-Vis) spectrophotometer and TEM. The produced nanoparticles show small and sharp plasmon peaks around 400nm and 500 nm for silver and gold respectively. The nanoparticles have spherical shape with average size of about 30 nm. The effect of gold and silver NPs was studied on the activity of acid phosphatase (ACP) in blood sera of healthy subjects. The result correlated with the observation that gold and silver nanoparticles had inhibition effect on serum acid phosphatase activity, and this effect increased with increasing the concentration of the nanoparticles.

حضرت الجسيمات النانوية النبيلة بواسطة القشط بالليزر في الماء. تم دراسةالخصائص البصرية والتركيبية للجسيمات المحضرة بواسطة المطياف والمجهر الالكتروني النافذ. الجسيمات النانوية تظهر حزمة بلازمونية حادة حول ال 400 و 050 نانومتر للفضة والذهب على التوالي وكذلك تمتلك حجم نانوي كروي بحدود 30 نانومتر. تم دراسة تاثير الذهب والفضة النانوية على انزيم ال ASP في مصل الدم لعينات صحية. اضهرت نتائج الارتباط ان جسمات الفضة والذهب تعمل على تثبيط فعالية الانزيم وهذا التثبيط يزداد بزيادة تركيز الجسيمات النانوية.

Keywords

Au --- Ag nanoparticles --- Acid phosphates --- Serum


Article
Evaluation The Serum Total Protein in Patients with Diabetes Mellitus (Type I and Type II) and Study Genetic Level of Glutathione-S-Transferaseµ 1

Authors: Nisreen Jalal Mohammed --- Moaed Emran AL-Gazally --- Maysam Ali Ameen Awadh
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2015 Volume: 12 Issue: 3 Pages: 625-631
Publisher: Babylon University جامعة بابل

Loading...
Loading...
Abstract

Diabetes mellitus is a group of metabolic diseasesdue to defect in insulin secretion or action or both.Hyperglycemia in diabetes creates free radicals .These free radicals produce oxidative stress and thus debilitate the endogenous antioxidant defense system.If the amount of insulin available is insufficient, cells response badly to the effects of insulin or if the insulin itself is abnormal. The net effect is persistently elevating levels of blood glucose, low protein synthesis.The current study evaluate the biochemical changes in diabetes mellitus patients in using different medications and investigate the glutathione S-transeferase M1 gene deletion in different treatments. The present study was conducted on (75) diabetic patients, (25) of them were treated with insulin, (25) were using insulin and metformin and the last (25) were on metformin and glibinclimide .The study also included (25) apparently healthy subjects were taken as control group. The blood sampleswere collected from Merjan Teaching Hospital from November 2013 to April 2014.The total serum protein was measured by colorimetric method described by Gornall.LSD test showed that there was significant difference between insulin & metformin group and metformin &glibinclimide in total serum protein (p ≤0.05). Metformin &glibinclimide group was less mean difference with the control group. In the gene level of the study, genotyping of glutathione S-transferase mu 1gene by PCR were defined as GSTM1 and GSTM0 or deletion association to the present and absences of the guanine nucleotide in the gene sequence. There was statistically significant difference in the genotyping distribution and the frequency of GSTM0 among study groups were 44% for insulin and metformin group, 68% for metformin and glibinclimide, 44% insulin and 28% for control healthy group.there was significant decrease in serum total protein in diabetic patients. Genetic polymorphism of glutathione S-transferase mu 1gene may be considered as risk factor for both types of diabetes mellitus.


Article
SERUM ZINC AS A RISK INDICATOR FOR ORAL HEALTH STATUS AMONG SECONDARY SCHOOL STUDENTS IN DUHOK KURDISTAN REGION , IRAQ
مستوى الخارصين في مصل الدم كعامل خطورة لصحة الفم ندى طلبة المدارس الثانوية في دهوك , اقليم كوردستان ,عراق

Authors: QAYSER SAHIB HABEEB --- ALI .H. AL-DOSKY علي الدوسكي --- HALA ANDRUOS YOUSIF هالة اندريوس يوسف
Journal: Duhok Medical Journal مجلة دهوك الطبية ISSN: ISSN: 20717334 (online)/ ISSN: 20717326 (Print) Year: 2015 Volume: 9 Issue: 1 Pages: 1-10
Publisher: University of Dohuk جامعة دهوك

Loading...
Loading...
Abstract

ABSTRACTBackground and Objective:In recent years there has been growing interest in understanding the exact role played by traceelements in several diseases. Particular attention has been paid to elements with possibleinfluence on oral health status like zinc. The wide inconsistencies about the subject and thepaucity of local studies in this context mandated the conduct of this study. The objective wasto investigate the relationship of serum zinc with oral health status.Materials and Methods:A cross sectional design enrolling eight secondary schools in Duhok city has been adoptedfrom 15th April to 15th June 2013. The sample comprised 280 (188 males and 92 females)apparently healthy students aged 18-23yrs. The study made use of blood samples collected ina previous study of Dr. Ali Hussein Ahmad. The same samples were used to determine thelevel of serum zinc. A questionnaire was used to obtain information on age, gender, medicaldiseases and drug history. This was followed by clinical dental examination to assess twostandard oral health indices, namely, Decayed, Missing, Filled Surfaces (DMFS) and gingivalindex (GI) for each student.Results:The mean serum zinc was (78.72 ± 13.54 g/dl) the value was higher in males and thedifferences were statistically significant ( p < 0.001).The mean DMFS was higher in femalesthan in males (12.08 ± 5.52 vs. 10.37 ± 5.84 respectively. P 0.02), while the mean GI washigher in males than in females (0.94 ± 0.77 vs. 0.49 ± 0.58 respectively. p < 0.001).Serum zinc was negatively correlated with both DMFS and GI, the correlation was strongerwith DMFS scores (r = - 0.9) than with GI scores (r = - 0.6).Conclusions: Different levels of serum zinc relate variably to oral health status. Serumzinc relates mainly to DMFS scores through a negative correlation.

خلفية البحث: ازداد في السنوات الاخيرة الاهتمام بفهم الدو ا رلدقيق للعناصر النزرة في العديد من الأم ا رض وقد اولي اهتمام خاص بالعناصر التي يحتمل تاثيرها في صحة الفم والاسنان مثل الخارصين. وبسبب التناقضات الواسعة حول هذا الموضوع وندرة الد ا رسات المحلية في هذا السياق تم أج ا رء هذه الد ا رسة. تهدف الد ا رسة الى تحري علاقة الخارصين بصحة الفم والاسنان.المواد والطرق: اعتمدت الد ا رسة التصميم المقطعي بضم ثمانية مدارس ثانوية في مدينة دهوك بالفترة من ١٥ نيسان الى ١٥ حزي ا رن ٢٠١٣ وقد شملت عينة البحث ( ٢٨٠ ) من الطلبة الاصحاء ظاهرياً ( ١٨٨ ذكور، ٩٢ أناث) وبأعمارت ا روحت ٢٣ ) عام اً. تم استخدام عينات دم كانت قد جمعت من خلال د ا رسة سابقة للدكتورعلي حسين احمد وقد - بين (١٨ أستخدمت نفس عينات الدم لتحديد مستوى الخارصين في مصل الدم لاغ ا رض هذه الد ا رسة. تم تنظيم أستمارة أستبيان للحصول على المعلومات المتعلقة بالعمر، الجنس، الأم ا رض السابقة والادوية المستخدمة تلا ذلك فحص للفم والاسنان لكل طالب. (GI) ومؤشر صحة اللثة (DMFS) لتحديد مؤشر تسوس وقلع وحشوة الاسطح للأسنان الدائمية ٧٨.٧٢) القيمة كانت أعلى لدى ± 13.54 g/dlμ) النتائج: اظهرت الد ا رسة ان مستوى الخارصين في مصل الدم كانأعلى لدى الاناث منه في (DMFS) كان معدل مؤشر .(p ˂ الذكور وكان التباين بمستوى احصائي معنوي ( 0.001 بينما كان مؤشر دالة (p = 10.37 ) وبمستوى احصائي معنوي ( 0.02 ± 12.08 مقابل 5.84 ± الذكور ( 5.52 0.49 ) وبمستوى احصائي عالي ± 0.94 مقابل 0.5 ± أعلى لدى الذكور منه في الاناث ( 0.77 (GI) صحة اللثة وكانت العلاقة (DMFS, GI) ان نسبة الخارصين في مصل الدم كانت تتوافق سلب اً مع مؤشري .(p ˂ المعنوية ( 0.001 (r = -0.6) GI منها مع مؤشر (r = -0.9) DMFS اقوى مع مؤشرالاستنتاجات: إن المستويات المختلفة للخارصين في مصل الدم تت ا ربط بشكل متغاير مع الحالة الصحية للفم. يرتبطمن خلال علاقة عكسية.

Keywords

serum zinc --- oral health --- students --- Duhok.


Article
Neovascularization in Psoriatic Patients

Authors: Zina Hammad Mohammed --- Yesar Mohammed AL-Shamma --- Hadi Abed Hadi Al-Wakeel
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2015 Volume: 12 Issue: 3 Pages: 638-645
Publisher: Babylon University جامعة بابل

Loading...
Loading...
Abstract

Although angiogenesis may not be the main event in the pathogenesis of psoriasis, identifyingthe pathways leading to angio-proliferation mayaid in discovery of novel antipsoriatic drugs. Vascular endothelial growth factor is a principal regulator of physiological and pathologicalneoangiogenesis.The aim of the study is to assess the serum level of vascular endothelial growth factor in psoriatic patients and its correlation with Psoriasis area and severity index score (PASI score). One hundred consentingpsoriatic patients(males and females)aged 20-60 years who attended different medical centers including Al-Sadr Medical City and department of laser research in AL-Najaf city and Marjan Medical City in AL-Hilla-Iraq.Psoriasis area and severity index assessment was done for each patient. Blood samples were collected for vascular endothelial growth factor measurement.The serum level of vascular endothelial growth factor was significantly increased in all groups of,psoriatic,patients comparedto healthy controls as well as serum vascular endothelial growth factor showed positive correlation with PASI score.


Article
Study of Serum Level of Interleukin 2
Interleukin 10

Author: Interleukin 10
Journal: journal of the college of basic education مجلة كلية التربية الاساسية ISSN: 18157467(print) 27068536(online) Year: 2015 Volume: 21 Issue: 90 / علمي Pages: 69-77
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract


Article
Cystatin (C) and its correlation to ischemic heart disease

Author: Dr. Basil N. Saeed
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2015 Volume: 11 Issue: 2 Pages: 15-16
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Cystatin C is recently considered to be a good predictor of cardiovascular morbidity and mortality in patients with coronary artery disease (CAD)Objectives: Correlation between cystatin and ischemic heart disease.Methods :One hundred forty patients (140) with ischemic heart disease admitted to thin study at Baghdad teaching hospital from the period June. 2011 to Jan. 2012. Those patients was categorized into three groups.Group (A): patients with ischemic heart failure.Group (B): Patients with myocardial infarction.Group (C) patients with unstable angina.All these groups were in comparison to fifty (50) healthy controls. Fasting serum citation (C) were measured in all patients and control in addition to all other routine investigations.Results: All results of serum cystatin C in all three groups of patients were higher in comparison to control group (P. value < 0.05) while it was not significantly different between the three groups (P. value 0.05)Conclusion: Cytstatin C can be used as prognostic biomarker in patients with ischemic heart and its complicated.


Article
Agaricus bisporous effect on Sugar, Cholesterol and the Bactericidal power of human serum
تأثير Agaricus bisporous على سكر, كولسترول والقوة المضادة للبكتريا في مصل الانسان

Author: Asal Aziz Tawfeeq أسل عزيز توفيق
Journal: Diyala Journal For Pure Science مجلة ديالى للعلوم الصرفة ISSN: 83732222 25189255 Year: 2015 Volume: 11 Issue: 1 Pages: 69-81
Publisher: Diyala University جامعة ديالى

Loading...
Loading...
Abstract

This research was carried out to study the effect of Agaricus bisporous mushroom on reducing the sugar and cholesterol in blood and determine its activity on improving the bactericidal power of serum collected from a group of healthy volunteers. So, about fifty healthy volunteers from both sexes ranging in age from (20-30 years) and of a weight between (65-100 kg) were included in this study.Results of nourishing (150g) of Agaricus bisporus mushroom as a diet to about (40) healthy volunteers from both sexes twice a week for two months did not show any change in body weight mass (BW) compared with the controls after two months of mushroom administration. However, a significant difference (P <0.05) in serum glucose and cholesterol concentrations in both (male and female volunteers of the study) was detected. In addition, the effect of Agaricus bisporus mushroom administration on the bactericidal activity of normal serum was also studied and a significant difference (P <0.05) in the bacterial colony counts especially in the colony counts of the bacterium Staphylococcus aureus was recorded. Moreover, the ethanolic extract of the Agaricus bisporous mushroom showed a significant (P <0.05) antibacterial activity against Staphylococcus aureus strains only.

تم اجراء هذا البحث لغرض دراسة تأثير فطر Agaricus bisporous على تخفيض السكر وكولسترول الدم وتحديد فعاليته في تعزيز القوة القاتلة للبكتريا في مصل الدم لمجموعة من المتطوعين الاصحاء. لذا تم اخذ نحو خمسين متطوعا من كلا الجنسين لهذه الدراسة تراوحت اعمارهم بين (20-30 ) سنة واوزانهم بين (65-100) كغم. وأظهرت نتائج التغذية لأربعين متطوعا بما يقارب ( 150 )غم من فطرAgaricus bisporous مرتين في الاسبوع ولمدة شهرين عدم حدوث اي تغيير في الوزن مقارنة مع مجموعة السيطرة واظهرت نتائج فحص الدم لمتناولي الفطر فرقا معنويا (P <0.05) في تراكيز السكر والكولسترول في الاناث والذكور من المتطوعين للدراسة مقارنة مع مجموعة السيطرة. بالإضافة الى ذلك , فقد تم دراسة تأثير فطرAgaricus bisporous على تعزيز قدرة المصل القاتلة للبكتريا وتم تسجيل فرقا معنويا(P <0.05) في عدد المستعمرات البكتيرية وخاصة في مستعمرات بكتريا Staphylococcus aureus. أيضا, فقد أظهر المستخلص الإيثانولي للفطر تأثيرا معنويا(P <0.05) مضادا لسلالات بكتريا Staphylococcus aureus فقط.


Article
Possibility of glucose level assessment using the blood of gingival probing and dental socket after tooth extraction
امكانية تقييم مستوى يأستخدام دم اللثه الناضح نتيجة اللثه والدم الناضح من مأخذ السن بعد القلع

Loading...
Loading...
Abstract

Background: The association between diabetes and inflammatory dental diseases had been studied extensively for more than 50 years. A large evidence base suggests that diabetes is associated with an increased prevalence, extent and severity of gingivitis and periodontitis and loss of teeth. Many patients do not aware that they are diabetic.Objectives:The aim of the current study was to assess a fast, non-invasive, safe procedure to screen for diabetes and its severity in dental clinics and to assess the change in blood glucose level before and after tooth extraction during periodontalResults: there were no significant differences between the blood samples collected before tooth extraction from finger puncture method (FPB) and the gingival crevicular blood (GCB) P ˃ 0.05Also there were no significant differences between finger blood glucose levels (FBGL) before and after the tooth extraction (P ˃ 0.05).There weresignificant differences between the blood samples collected after tooth extraction from finger puncture method(FPB)and the socket blood (SB), P ˂0.05.There were highly significant differences between the gingival crevicular blood (GCB) before tooth extraction and the socket blood (SB)after tooth extraction P˂0.01.Conclusion: The data of this study has shown the followings the gingival crevicular blood could be an excellent source of blood for glucometric analysis. The blood obtained from the socket of the extracted tooth is undependable for glucometric analysis. There is no effect of tooth extraction procedure on the blood glucose level of the controlled diabetic patients

الخلفيه: الارتباط بين مرض السكري والامراض الاتھابية واللثة موضوع تمت دراسته بشكل موسع لاكثر من خمسين سنة. ھناك مؤشرات كثيرة تشير الىالارتباط بين مرض السكري وارتفاع الاصابة بأمراض اللثة وما حول الاسنان وكثير من المرضى لا يعملون انھم مصابون بمرض السكري.الھدف من ھذهالدارسة ھو تقييم طريقة سريعة وامنية مؤذية للكشف عن مرض السكري في عيادات طب الاسنان وكذلك تقييم التغير الحاصل على مستوى السكر قبل وبعد(ACCU –CHECK , ROCHE قلع السن من خلال الفحص الروتيني للقة وقلع الاسنان الغير قابلة لعلاج اخر بأستخدام جھاز فحص السكر الشخصي( تم اشتراك ( ٥٠ ) مريض بھذه الدراسة ، جميعھم مصابون بمرض السكري من النوع الثاني ، ( ٢٣ ) رجل و ( ٢٧ . DIAGNODTIC M , GERMANEY)٦٠ ) سنة.في البداية تم قياس نسبة السكر قبل اعطاء المخدر الموضعي بأستخدام عينة دم مأخوذة عن طريق وخز الاصبع - امرأة تتراوح اعمارھم بين ( ٣٠وبعد ذلك تم اخذ عينة الدم الناضح من اللثة من فحص اللقة بالمجس ، وقد تم جمع العينة بأستخدام أنبوب بلاستيكي قطرة ( ٢ملم) ، وايضا تبع ذلك اخذ عينة

Listing 1 - 10 of 25 << page
of 3
>>
Sort by
Narrow your search

Resource type

article (25)


Language

English (20)

Arabic and English (5)


Year
From To Submit

2015 (25)