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Histological and histomorphometric studies of the effects of hyaluronic acid on osseointegration of titanium implant in rabbits

Authors: Mohammad Hasan Mohammad محمد حسن محمد --- Nada M. H. Al-Ghaban ندى الغبان
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2018 Volume: 30 Issue: 2 Pages: 10-16
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: One of the unique prosthesis for tooth or teeth replacement is the dental implant. Our attempt is using a biomaterial system that is easily obtained and applicable and has the ability to provoke osteoinductive growth factor to enhance bone formation at the site of application. One of these natural polymers is hyaluronic acid. Material and methods: Sixty machined surface implants from commercially pure titanium rod inserted in thirty NewZealand rabbits. Two implants placed in both tibia of each rabbit. The animals scarified at 1, 2 and 4 weeks after implantation (10 rabbits for each interval). For all of animals the right tibia’s implant was control (uncoated) and the left one was experimental (coated with 0.1ml Hyaluronic acid gel). All sections have been stained with Haematoxylin and Eosin then they were histologically examined and assessed for histomorphometric analysis for counting of bone cells (osteoblast, osteocyte and osteoclast), cortical bone thickness, trabecular width, thread width and marrow space star volume (V*).Results: Histological findings for hyaluronic acid- coated titanium implant revealed an earlier bone formation, mineralization and maturation than that in control groups. Histomorphometric analysis for all bone parameters that examined in this study, showed highly significant difference between control and experimental groups in all healing intervals.Conclusion: Commercially pure titanium endosseous implants coated with hyaluronic acid may be osteocoductive thus accelerating healing process and enhancing osseointegration


Article
Evaluation of related factors affecting stability and survival rate of dental implants (meta-analysis of retrospective study)

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Abstract

Aims: evaluate survival rate of dental implants. Determine correlations between bonedensity and stability. Determine which intervention to dental implant that increasestability.Materials and methods: Retrospective study of patients receiving implants in dentalimplant unit in educational hospital of collage of dentistry /Baghdad Universityduring period October 2012- October 2015. Individual data meta-analysis ofimplants stability using different interventions, which Are bone morphogeneticproteins, immediate dental implant, Ridge splitting, simvastatin drug, Platelet-Rich Plasma, Piezosurgery and control group.Results: survival rate was 98.33%. Implant length and posterior location statisticallysignificant effect on achieving high stability in control group. Posterior locationstatistically significant increase primary stability. After 2 months of surgerycomparing interventions and control group show simvastatin(P<0.001) increasestability and among variables diameter, length and mandibular locationstatistically significant increase stability. After 3 month simvastatin(P<0.001) andBone morphogenetic proteins(P=0.005) increase stability and mandibular location,length and diameter increase stability. After 4 months Piezosurgery statisticallysignificant lowering stability (P=0.004), and diameter statistically significantincrease stability.Conclusions: High survival rate achieved. No significant effect of variables onfailure rate of implants. Simvastatin and Bone morphogenetic proteins reducehealing time and improve stability but Piezosurgery lowering stability comperedto control. Posterior location affected primary stability but length and diameterincrease secondary stability. Bone density had no effect on primary and secondarystability.


Article
Bacteriological Findings within Internal Implant Hole Following Flapless Implant Placement

Authors: Abbas S.AL-Mizraqchi --- Basima GH. Ali --- Khudair Ali Abd
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2018 Volume: 30 Issue: 3 Pages: 13-16
Publisher: Baghdad University جامعة بغداد

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Abstract

Back ground: Microbial penetration inside the implant's internal hole creates a bacterial reservoir that is related with an area of inflamed connective tissue opposite the fixture-abutment junction and this can affect the health of the peri-implant tissue.Aims of the study: Evaluate the types aerobic and anaerobic bacterial count-percentage and difference between Aerobic and Anaerobic microflora in the implant screw hole three months after implant placement. Monitor the periodontal health status of all patients, throughout the study.Material and methods: Study methodology; Eight partially edentulous patients received 20 dental implants and these implants done with flapless surgical procedure. All patients examined clinically to determined their oral health status by examination of their plaque index, Gingival index and Bleeding on probing, each two weeks for 90 days (8visits) throughout the study period. Three months after that, the plaque sample collected from the internal hole of fixture and transfer to bacterial investigation and assessment the amount of anaerobic and aerobic bacteria.Results: Although the anaerobic viable count is higher than that of aerobic, but with statistically not significant difference between those counts (P>0.05).

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