Background Hemangiopericytoma (HPC) is an uncommon vascular neoplasm.Objectives This study was designed in order to review and summarize published cases with oral HPC since 1949, and unpublished cases from histopathological centers in Kurdistan region/Sulaimani/Iraq. The specifc objective is to correlate cases related medical data with treatment option and prognosis. Materials and Methods A web-based search was initiated for published articles and case reports by using PubMed, and Google. Another search was done in the database of histopathological centers in Sulaimani. Results Two new cases of oral HPC diagnosed in the Department of Oral and Maxillofacial Pathology - Dentistry College - Sulaimani University were reported in details. Literature review disclosed sixty-six HPC of the oral cavity and additional fve cases were reported from Sulaimani (total 71 cases). Male to female ratio was 1:1.5, with a wide age range from newborn to 91 years, 50% of oral HPC was between 15 and 51 years. The tongue was the most common site that HPC originated from, then jawbones, and buccal mucosa. Neither sex nor age seems to have any effect on the outcome of oral HPC (p>0.05). HPCs that originate from oral mucosa including 13 cases from buccal mucosa and gum were benign, while jaw bones HPC was with malignant behavior in six cases. The behavior of twenty-six cases was not recorded. Different sites had no effect on the tumor outcome (p=0.08). Most cases which were treated only by surgery showed no recurrence (p=0.01). Conclusion HPC has a high rate of recurrence with undeterminable malignant potential, and require surgical excision with adequate margins and long-term follow up.

Oral --- Benign --- Malignant --- Hemangiopericytoma --- HPC --- Vascular tumor --- Analytic study