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Article
EFFECTS OF TESTOSTERONE HORMONE ON STRUCTURE OF UTERUS IN FEMALE MICE BALB/C
تأثير هرمون التيستوستيرون على تركيب الرحم في إناث الفئران المختبرية

Author: Emad. k .Abbas عماد خضير عباس
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2012 Volume: 11 Issue: 2 Pages: 66-73
Publisher: Basrah University جامعة البصرة

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Abstract

This study shows the effects of Testosterone hormone on uterus tissue in female mice. We used twenty laboratory mice (Ten animals for each group). The first groups used as a control by using physiological saline (0.9%) concentration. The second groups were taken the 10mg/kg for 28 days. Biopsy was taken from the animals to examine their tissue histopathologically, Results were seen in uterus form of degradation in Endometerium and bleeding .Deteriorate in epithelial tissue and infiltration in inflammatory cells .

أجزيج هذ انذراست ن عًزفت حأريز هزيى انخيسخىسخيزو عهى سَيج انزدى في إ بَد انفئزا حى اسخخذاوعشزو ي أ بَد انفئزا ان خًخبزيت حى حقسي هًب عشىائيب انى يج ىًعخي )عشزة نكم يج ىًعت ( اعخبزث ان جً ىًعتالأونى يج ىًعت سيطزةوديذ دق جُ ببن ذًهىل انفسيىنىجي أيب ان جً ىًعت انزب يَت فقذ دق جُ بهزيى انخيسخىسخيزو 10 يهغى/كغى ي وس انجسى ون ذًة ر بً يَت وعشزي يىيب حى انخضذيت ببنذيىا بَث في هَبيت انخجزبت وأخذث ي هُبعضى انزدى نع مً ان قًبطع ان سُجيت وح زًهج انعلايبث ان زًضيت في سَيج انزدى نفئزا ان جً ىًعت انزب يَت بذصىلدبنت انخذهم في انطبقت ان بًط تُ نهزدى يع دبنت ان شُف وكذنك دبنت انخهف نهطبقت انطلائيت يع دبنت أرحشبح نهخلايبالانخهببيت

Keywords

Testosterone --- uterus --- female mice


Article
Pattern of Skin Disorders Among Female Secondary School in Fallujah City
دراسة الأمراض الجلدية ضمن طالبات المدارس الثانوية في مدينة الفلوجة

Author: Asma I Alajeel اسماء ابراهيم العجيل
Journal: Al- Anbar Medical Journal مجلة الأنبار الطبية ISSN: PISSN: 27066207 / EISSN: 26643154 Year: 2012 Volume: 10 Issue: 2 Pages: 19-25
Publisher: University of Anbar جامعة الانبار

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Abstract

Introduction: Adolescence is the transitional stage of physical and mental human development that occurs between childhood and adulthood. The pattern of skin disease in general varies in frequency and severity in different age groups and it differ with geographical locations due to environmental, race factors, sex and age. Objective: To determine the pattern and severity of skin disease among adolescent female students in Fallujah city in order to understand the effect and the impact of skin diseases at this stage of life.Patients and Methods: This is a cross sectional study of 400 adolescent female students with skin diseases in Fallujah secondary schools. The study was performed during the period from November 2009 - May 2010. The students were examined for the type of skin disorder and its severity. Results: The majority of the patients had one skin disorder 62%; the remainder had 2 or more disorders. The most common skin diseases and conditions were the disease of skin appendages (with the acne being the most common one) followed by dermatitis and related conditions and then skin infections.Acne was noticed in (30%) of students, affecting the face (95.5%) and trunk (4.5%). The next common disorder was hirsutism (25%), atopic dermatitis, (15%), diffuse hair loss (10%), dandruff (7.5%), warts (7. 5%) and (scabies 7%).A large number of acne patients had also hirsutism and to lesser extent dandruff and Androgenetic alopecia and these patients were found to have high free testosterone level and ultrasound appearance of polycystic ovary (PCO) which pointed to the diagnosis of Polycystic ovary syndrome (PCOS).Conclusion: Skin diseases are common among adolescent female students in Fallujah city. The most common skin disorders at this age were acne and hirsutism which is of cosmetic importance, so early and proper management of these disorders is important to prevent the late disfiguring sequel and psychological problems.

المقدمة : المراهقة هي الفترة الانتقالية من التطور الفيزيائي والذهني للإنسان والتي تحدث بين الطفولة والبلوغ . ان نمط المرض الجلدي بصورة عامة يختلف في المعدل والشدة بالنسبة للأعمار المختلفة والاماكن الجغرافية بسبب العوامل البيئية والعرقية والجنس والعمر.الهدف : تحديد نمط وشدة الأمراض الجلدية بين طالبات الثانوية في مدينة الفلوجة / العراق لبيان تأثير الأمراض الجلدية في هذه المرحلة العمرية .اجريت هذه الدراسة على 400 طالبة ثانوية في مدينة الفلوجة , خلال الفترة من تشرين الثاني 2009 الى أيار 2010 . النتائج : الغالبية من الطالبات كان لديهن حالة مرضية واحدة(62%) بينما البقية لديهن اثنتين او اكثر من الحالات. ان اكثر الحالات الجلدية شيوعا هي امراض لواحق الجلد وكان مرض حب الشباب هو الاكثر شيوعا تتبعها الحالات الجلدية .التحسسية ثم الالتهابات الجلدية. حب الشباب لوحظ في 30% من الطالبات( 95.5 في الوجهة و4.5 في الظهر)% , يليه حالة الشعرانية 25% , ثم الحساسية الأتوبية 15% , فقدان الشعر الواسع 10%, داء القشرة 7.5% , الثألول 7.5% والجرب 7%. عدد كبير من المصابات بحب الشباب كان لديهن حالة الشعار وبنسبة اقل داء القشرة وحالة تساقط الشعر الذكوري، وعثر على أن هؤلاء الطالبات لديهن ارتفاع في مستوى هرمون التستوستيرون الحر والفحص بالموجات فوق الصوتية اظهر نتيجة المبيض المتعدد الكيسات (PCO) والتي تشير إلى تشخيص متلازمة تكيس المبيض (PCOS).الأستنتاجات :- إن الأمراض الجلدية شائعة بين طالبات الثانوية في مدينة الفلوجة وان حب الشباب و الشعرانية هما السائدان في هذه الفئة العمرية والتي تشكل اهمية من الناحية الجمالية لهذه الفئة من البنات , لذلك فأن المعالجة المبكرة والسليمة لهذه الحالات تكون على قدر من الاهمية لمنع النتائج المشوهة والنفسية.

Keywords

skin --- female --- students


Article
CHARACTERISTICS AND CLINICAL MANAGEMENT OF FEMALE PATIENTS WITH FISSURE IN ANO IN AL-KADHIMIYA CITY, BAGHDAD

Author: Qahtan A. Mahdi قحطان عدنان مهدي
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2013 Volume: 11 Issue: 3 Pages: 238-242
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background:Fissure in ano is a common painful anal problem in female patients.Objective:To study the sociodemographic variables of female patients with fissure in ano, and to identified the characteristic of anal fissure and their treatment among those patient in Al-Imamian Al-Kadhimiyian Medical City and two private hospitals.Methods:This is a prospective study that was carried out from May 2008 to May 2011. Two hundred fifty female patients with fissure in ano were interviewed regarding their age, marital state, address, level of education, clinical presentation and the subsequent management.Result:The commonest age of presentation in females was between 21-30 years. 78% of them were living at the peripheral areas of north of Baghdad, and 79.6% were of low level of education (primary school or below). The prevalence was found more in women with high parity especially when their child delivery was supervised by a midwife in their location. All patient has presented with anal pain, 55% were associated with bleeding per rectum and 64.2% with constipation. The location of fissures was 51.6% anterior, 48% posterior, 0.4% lateral in position. Less than half of patients underwent a surgical treatment. 77% of them were treated by lord dilatation under anesthesia and 23% by lateral sphinecteromty.Conclusion:Factors which had an impact on the clinical course and management of fissure in ano in female patients were found to be the social status, the level of education and the parity, therefore to prevent this illness, a cooperation between the heath services and the family health center and the government is necessary in order to overcome such a common problem.Keywords:Fissure in ano, Female

Keywords

Fissure in ano --- Female


Article
Anal Fissure among Female in Erbil City
الشق الشرجي عند الإناث في مدينة أربيل

Author: Bahjat Ahmed Mohammad
Journal: kufa Journal for Nursing sciences مجلة الكوفة لعلوم التمريض ISSN: 22234055 Year: 2013 Volume: 3 Issue: 3 Pages: 21-25
Publisher: University of Kufa جامعة الكوفة

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Abstract

Objectives: to identify the causes of the fissure in ano among child bearing age female in Erbil city because it is very common in the Kurdistan.Methods :- This prospective study of evaluation of fissure in ano among female patients in Erbil city and its surrounding for the period between may 2010 and may 2012, Data collected from 500 cases showed that fissure in ano is most common cause of ano-rectal pain in this locality among child bearing age females from clinic ,Erbil teaching hospital and Erbil gynecological hospital All the patients were interviewed and clinical data were recorded including; age, occupation, marital state, number of children, types of fissure in ano, sites of fissure, associated symptoms, its treatment and recurrence. Period from first onset of symptoms to first medical consultation were recorded and showed that most of them were delayed.Results: from 500 cases showed that fissure in ano is most common cause of ano-rectal pain in this locality among child bearing age females from clinic ,Erbil teaching hospital and Erbil gynecological hospital.Conclusion: the fissure in ano is the most common disease among female childbearing age and usually due to bad post natal careRecommendation: for prevention of this painful condition I advice the gynaecologist and obstetrician to do peri anal care.

الأهداف: هذه دراسة وصفية أجريت لتقييم حالات الفطر الشرجي بين النساء في مدينة اربيل و ضواحيها, الفطر الشرجي هو مشكلة شائعة بين النساء اكثر مما هو في الرجال, وهو تقرح خطي في النصف الأسفل من القنات الشرجية الواقعة في الجدار الخلفي والوسطي.المنهجية: جمعت المعلومات من 500 حالة للفترة الممتدة من ايار 2010- الى ايار 2012 من خمسمائة مريض اجروا مقابلة والفحص السريري وتم تسجيل المعلومات السريرية وكانت تتضمن العمر , محل الإقامة, الوظيفة, الحالة الاجتماعية, عدد الأطفال نوع وموقع فطر الشرجي وكذلك الأعراض المصاحبة والعلاج ورجوع الفطر بعد العلاج مرة أخرى. بالإضافة الى ذلك تم احتساب الفترة الزمنية بين ظهور أول عرض للمرض ومراجعة المريضة للطبيب لغرض العلاج. النتائج: الفطر الشرجي حالة متكررة بين النساء القادرات على الحمل وأظهرت النتائج من مجموع الحالات 76.8% منهم كانوا متزوجات و23.3% كانوا غير متزوجات.الاستنتاج: عدد الأطفال ومكان الولادة والعوامل الاجتماعية والتعليمية هي من العوامل المشاركة في تطور المرض.التوصيات: يجب زيادة التوعية الاجتماعية لهذه المشاكل ومضاعفاتها.

Keywords

fissure --- ano --- female.


Article
REPRODUCTIVE EFFICACY IN FEMALE RAT EXPOSED TO BISPHENOL A DURING GESTATION PERIOD
الكفاءة التكاثرية في اناث الجرذان المعرضة للبسفينول خلال فترة الحمل

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The study was conduct to determine the effect of exposure to Bisphenol A (BPA) during gestation on serum reproductive hormones levels (Estradiol" E2", Luteinizing Hormone "LH" and follicle- stimulating Hormone" FSH"), age and weight at vaginal opening onset as well as reproductive efficacy in F1 female offspring.Thirty six pregnant female rats (F0) were gavage three doses of BPA suspended in corn oil (50 μg, 50 mg, 250 mg/kg/BW) or corn oil only as control group from gestational day (GD) 6 till gestation day (GD) 21. After delivery, twelve female pups of each group were hold for three months; However, Female rats' offspring, after weaning, were weighed and checked for vaginal opening (VO) every day until completion, then at postnatal day (PND) 90, blood samples were collected from six F1 female of each group to perform hormonal tests and other six females were mated with untreated male rat in a separate cage for 14 days in order to evaluate fertility efficacy. The results showed significant increased (P<0.05) in serum E2 levels, and decrease in LH level, but FSH levels were unchanged in all treated groups compared with control group. The results also revealed significant decrease age at VO onset in all treated groups compared with control group , while body weight at age of VO onset was non-significantly differ between all groups.Fertility rate, number of birth and implantation sites were reduced and resorption sites were elevated in F1 female rats that gestationally exposed to deferent levels of BPA in comparison with control group. From the present study it has been revealed that the BPA exposures during pregnancy adversely affect F1 female reproduction and caused early puberty onset.

Keywords

Estradiol --- BPA --- Female


Article
MEDICO-LEGAL STUDY OF VIOLENCE AGAINST FEMALES

Authors: Ban S.A. Al-Saadi بان صبيح علوان --- Saad K. Al-Giboori سعد كاظم كريم
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2015 Volume: 13 Issue: 1 Pages: 84-89
Publisher: Al-Nahrain University جامعة النهرين

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Background:Violence against female is an important and serious public health and medico-legal problem. It carries important risk factor related to ill health of female and its consequences on physical, social, mental and reproductive health of women.Objectives:To determine the type of fatal and non-fatal intentional injuries involving women, girls and young female kids and method used for such injuries and to reveal the magnitude of domestic violence of both physical and sexual types.Methods:A cross-sectional study was carried out within 6 months period on 82 medico-legal female cases with intentional violence. All females (living and postmortem cases) were studied. Information was collected from the same victim or her relative (in non-living cases) through an interview, police reports and their medical reports. Digital photography was done for some interesting cases while radiological survey followed by complete autopsy for all non-living cases.Results:The study showed that 57.3% were living subjects while 42.7% were postmortem victims. Regarding the living cases, their mean age was 20.61±9.37 years. Illiteracy constitutes 57.4% of them. All of them were referred as cases of violence directed to the genital area (sexual assault) but 72.3% were with no tear to the hymen. In post-mortem victims, the mean age was 28.6±12.84years. Housewives constituted 85.7% of them and 45.7% were having primary school level of education only. Burn was the main type of injury constituting 71.4%. In 65.71% were affected by sexual assault and in 69% of victims there were old hymen tears. In 80% death was due to suicide.Conclusion:Violence was more common among living female and highest in the third decade of life. Majority were either with low level of education or having primary school level of education. All of the living females were sexually assaulted while burn was the main type of injury among the postmortem group.Key words:Violence, Hymen, women, female.

Keywords

Violence --- Hymen --- women --- female


Article
Treatment of low serum ferritin in females with alopecia by oral iron.

Authors: Wisam Ali Ameen --- Hassanain H. Al-Charrakh
Journal: Iraq Joural of Hematology المجلة العراقية لامراض الدم ISSN: 20728069/25432702 Year: 2015 Volume: 4 Issue: 1 Pages: 126-136
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Background: Hair loss affects over 25% of women in developed countries. Three hairdisorders, androgenetic alopecia, telogen effluvium and alopecia areata which account formost cases of nonscarring alopecia in women. Iron deficiency has been reported in themajority of women presenting with diffuse hair loss. Iron has important function in oxidationreductionreactions, collagen synthesis, and as a co-factor for enzymes.Objectives: To assess the percentage of the low serum ferritin hair loss females and theirresponse to oral iron replacement therapy.Materials and methods: a prospective cohort study conducted in at Marjan teaching hospitalfrom August 2013 to January 2015. It included 72 female complained from diffuse hair losswere enrolled in this study. Full history was taken from all patients and physical examinationswere done both general examination and local examination of the scalp including pull test.Patients were sent to complete blood examinations, serum ferritin. Patients divided in to threegroups according to their response to treatment. Before the treatment the severity of hair losswas assess by VAS.Results: Fifty two patients met criteria of inclusion. Their serum ferritin levels range between(1.4-14.4) with mean 6.16±3.30 their hemoglobin levels were (8.3-13.4) with mean ±SD11.98±1.22. Group I patients included 27 patients (51.9%), their severity of hair loss beforetreatment was assess by VAS which was 9.18±0.84, after two week of treatment the scorebecome 7.33±1.03, P value is < 0.0001; confidence interval 95% = ( 1.477 to 2.277). in groupII patients which included 12 patients (23%), their severity of hair loss before treatment wasassess by VAS which was 9.33±0.49, after two week of treatment the score become 9.08±0.66,P value is 0.081 considered not significant; confidence interval 95% = (-0.037 to 0.537). Theother thirteen patients (25%) represented the third group. All the patients in this group didn’tshow any response to treatmentConclusion: Measurement of serum ferritin level should be done to all patients with chronictelogen effluvium before starting other anti-hair loss modalities. Iron replacement is a safedrug with a few side effects and indicated to all females with low serum ferritin level.

Keywords

ferritin --- female --- hair loss


Article
The effect of crude alcoholic extracted for the Seeds and Leaves of Apium graveolens Var dulce. In the level of some female hormones in albino Mice.
تأثير المستخلصات الكحولية الخام لبذور واوراق الكرفس var Apium grveolens dulce على مستوى الهرمونات الانثوية في الفئران البيض

Authors: Rassmiya H. Murad رسمية حياوي مراد --- Shalal M.H.AL-Atabe شلال مراد العتابي
Journal: Baghdad Science Journal مجلة بغداد للعلوم ISSN: 20788665 24117986 Year: 2012 Volume: 9 Issue: 1 Pages: 7-17
Publisher: Baghdad University جامعة بغداد

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The quantitative determination of the estrogen E2, Progestron P4 & follicle stimulating hormones FSH in the serums of Albino mice used in the experiments & treated by crude alcoholic extracted 95% of the seeds & leaves of Apium graveolens was a significant increase in the concentration of estrogen of different kinds of the extracted in comparison with the values of the coefficient of the control group, that is the study recorded a significant increase of the concentration of estrogen; it was the highest in the mice which was administrated by the methanolic extracted 95%, then it was less in the mouse which was administrated by the ethanolic extracted., and it was the least in the mice which were administrated by the crude ethanolic-methanoloic extracted of the seeds of Apium graveolens; while the increase of the concentration of estrogen of different crude alcoholic extracted leaves of Apium graveolens was the highest than the extracted of the seeds, & it was less concentration in the mice which were administrated by the methanolic extracted 95%, & then it was the least in the mice which were administrated by the crude ethanolic-methanolic extracted leaves of Apium graveolens in comparison with the values of the control group.Further, the plant extracted created a significant increase of the concentration of progestron P4; the statistics analysis recorded that the concentration of progestron was the highest in the mice which were administrated by the methanolic extracted 95%, then it was less in the mice which were administrated by the ethanolic extracted 95%, and the least in the mice which were administrated by the crude ethanolic-methanolic extracted of the seeds of apium graveolens whereas, a significant increase of the concentration of progrstrone was recorded in the leaves of Apium graveolens as follows: it was the highest in the mice which were administrated by the ethanolic extracted 95%, then it was less in the mice which were administrated by the crude methanolic extracted 95%, and it was the least in the mice which were administrated by the crude ethnolic-methanolic extracted in comparison with the coefficient of control group.The study also proved that there was a significant increase of the concentration of the follicle stimulating hormone FSH whose greatest concentration in the mice which was administrated by the crude ethanolic-methanolic for the seeds of Apim graveolens, it was less concentration in the mice which was administrated by crude methanolic extracted 95% of the seeds, and it was the least in the mice which was administrated by the methanolic extracted 95% of the leaves of Apium graveolens in comparison with the concentrations of the coefficient of the control group. While, the results recorded a significant decrease of the FSH in the mice which was administrated by the crude ethanolic extracted of the seeds & leaves of Apium graveolens a highest decrease, it was less concentration in the mice which was administrated by the crude ethanolic-methanolic extracted of the leaves of apium graveolens, in comparison with the concentration in the control group.

استهدفت الدراسة الحالية التحديد الكمي Quantitative determination لهرمون الاستروجين والبروجسيترون والهرمون المحفز للجريبات في مصول إناث الفئران البيض المعاملة بالمستخلصات الكحولية الخام 95% لاوراق وبذور نبات الكرفس. إذ اظهرت نتائج الدراسة ارتفاع معنوي(P<0.001) في تركيز هرمون الاستروجين لانواع المستخلصات قياسا مع قيم مجموعة السيطرة حيث شملت زيادة معنوية بتركيز هرمون الاستروجين في المستخلص الميثانولي 95% تلاها المستخلص الايثانولي 95%، ثم المستخلص الايثانولي-الميثانولي الخام لبذور الكرفس، بينما كانت الزيادة بتركيز هرمون الاستروجين بالنسبة للمستخلصات الكحولية لاوراق الكرفس في المستخلص الايثانولي 95% اولاً، يليه الميثانولي 95%، ثم يليه المستخلص الايثانولي الميثانولي الخام لاوراق الكرفس عند مقارنتها بالسيطرة. كما احدثت المستخلصات النباتية ارتفاع معنوي[P<0.01] في تركيز هرمون البروجستيرون مقارنتاً بالسيطرة، إذ سجلت الاحصائيات ارتفاعاً معنوياً بتركيز الهرمون في المستخلص الميثانولي 95% يليه المستخلص الايثانولي 95% ثم المستخلص الايثانولي – الميثانولي الخام لبذور الكرفس، بينما سجلت الزيادة بتركيز هرمون البروجستيرون في المستخلص الايثانولي 95% تلاها المستخلص الميثانولي الخام 95% ، ثم المستخلص الايثانولي – الميثانولي الخام لاوراق الكرفس عند مقارنتها بقيم مجموعة السيطرة. كما سجلت الدراسة ارتفاعاً معنوياُ[P<0.05]في تركيز الهرمون المحفز للجريبات FSH بلغت هذه الزيادة ذروتها في المستخلص الايثانولي-الميثانولي الخام، يليه المستخلص الميثانولي 95% لبذور الكرفس،ثم المستخلص الميثانولي 95% لاوراق الكرفس عند مقارنتها مع مجموعة السيطرة، بينما سجلت النتائج انخفاضا ًمعنوياً[P<0.01] في مستوى الهرمون المحفز للجريبات FSH في المستخلص الايثانولي الخام لبذور الكرفس واوراقه يليه المستخلص الايثانولي – الايثانولي الخام لاوراق الكرفس عند مقارنتها بالسيطرة


Article
Vesical stones in females: An underestimated problem in Mosul Province
الحجارة المثاني في الإناث: هناك مشكلة الاستهانة في مقاطعة الموصل

Author: Zaid Saad eldin Khudher, Nooman Hadi Saeed, Ahmed khalil Ibrahim
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2013 Volume: 19 Issue: 1 Pages: 107-113
Publisher: Tikrit University جامعة تكريت

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Abstract

Objective: Vesical stones may be associated with significant urological symptoms and may reflect more serious underlying urological or systemic problems. The aim of this study is to discuss the trends of vesical stones in women, diagnostic tools, and their management patterns. Patients & methods: A cross-spective study of 25 female patients, presented with vesical stones, from the urology department at Al-Jumhoori teaching hospital in Mosul. History, physical examination, laboratory & radiological investigations were performed trying to confirm the diagnosis & look for any possible underlying etiology. Then the treatment modality( open surgery versus endoscopic intervention ) was decided with regard to stone(s) size, number, the patients age & facilities available in the center. The results were analyzed accordingly. Results: The mean patients age is 31.2 years. They presented with a mix of symptoms that mainly included irritative voiding symptoms, suprapubic pain, & hematuria. Ultrasound was the most sensitive imaging modality used. Primary vesical stone was found in 64% of cases, & secondary stone in 36%. Cystolitholapaxy was the treatment of choice in 64% of patients & cystolithotomy in 36%. Conclusion: Female vesical calculi have their on trend of behavior that do differ from what is being found in male patients. They present earlier in life (almost 2/3 before 40years of age), commonly are idiopathic in origin, usually have less acute pattern of presentation as compared to male patients. They can be safely & precisely diagnosed using ultrasound & successfully treated by cystolitholapaxy, although cystolithotomy still have its own indications.

الهدف : قد تترافق مع أعراض حصى المسالك البولية المثانية كبير و ربما يعكس مشاكل المسالك البولية أو النظامية أكثر خطورة الكامنة. الهدف من هذه الدراسة هو مناقشة الاتجاهات من الحجارة المثاني في النساء ، أدوات التشخيص ، و أنماط إدارتها. المرضى و الطرق : دراسة عبر spective من 25 مريضا من الإناث ، قدم بالحجارة المثاني ، من قسم جراحة المسالك البولية في آل Jumhoori تعليم مستشفى في الموصل. أجريت التاريخ ، والفحص البدني ، والمختبرات و الإشعاعية التحقيقات في محاولة للتأكد من التشخيص و البحث عن أي مسببات الكامنة ممكن. ثم تقرر طريقة العلاج ( الجراحة المفتوحة مقابل التدخل بالمنظار ) فيما يتعلق الحجر (ق ) الحجم و العدد، سن المرضى و التسهيلات المتاحة في المركز. وقد تم تحليل النتائج وفقا لذلك . النتائج : المرضى متوسط ​​العمر هو 31.2 سنة. قدموا مع مزيج من الأعراض التي شملت أساسا يفرغ مهيج الأعراض، و الألم فوق العانة ، و بيلة دموية . كان الموجات فوق الصوتية طريقة التصوير الأكثر حساسية المستخدمة. تم العثور على حجر المثاني الأساسي في 64 ٪ من الحالات، والحجر الثانوية في 36 ٪ . كان Cystolitholapaxy العلاج الأمثل في 64 ٪ من المرضى و استخراج حصاة المثانة في 36 ٪ . الاستنتاج : الحصوات المثانية يكون أنثى على الاتجاه السلوك التي لا تختلف عن ما يتم العثور عليها في المرضى الذكور . ما يقدمونه في الحياة في وقت سابق ( تقريبا 2/3 قبل من 40years من العمر) ، هي مجهولة السبب عادة في الأصل ، وعادة ما يكون أقل حدة من نمط العرض بالمقارنة مع المرضى الذكور . يمكن أن يكون بأمان و بدقة تشخيص باستخدام الموجات فوق الصوتية و معالجتها بنجاح من قبل cystolitholapaxy ، على الرغم من أن استخراج حصاة المثانة لا تزال لديها مؤشرات خاصة بها .


Article
THE EFFECT OF SODIUM FLUORIDE ON HISTOLOGICAL CHANGES
تأثير فلوريد الصوديوم NaF في التغييرات النسجية للمبيضين وقرني الرحم في الفئران

Author: حسام جاسم حسين بنانة
Journal: Iraqi Journal of Biotechnology المجلة العراقية للتقانات الحياتية ISSN: 18154794 Year: 2008 Volume: 7 Issue: 2 Pages: 147-156
Publisher: Baghdad University جامعة بغداد

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Abstract

The present study was conducted to identify the effect of oral administration of sodium fluoride (NaF) on histological changes of ovarian and uterine horns in mice. Sixty four mature female Swiss albino mice, Balb/C were divided into four major groups including control (C) group and treatment groups (T1 , T2 and T3) according to NaF dose as following 0 ppm, 200 ppm, 400 ppm and 600 ppm , respectively. Each major group was subdivided into two minor groups according to the period of administration in 10 and 15 weeks. Therefore, each minor group contains eight females. Histological changes were assessed includes ovarian diameter, number and diameter of growing ovarian follicle (GOF), Graafian follicles (GF) and corpus luteum (CL), diameter of uterine horn (UH), thickness of epithelial cell layer (ECL) lining the UH and diameter of uterine glands (UG).The results of ovarian histological changes showed a highly significant (P<0.01) reduction in the ovarian diameter, number and diameter of GOF, GF and CL for all treated groups T1, T2 and T3 as compared to control for both treatment periods (10 and 15 weeks). Within same treatment periods, histological examination of uterine horn observed highly significant (P<0.01) reduction in the diameter of UH, thickness of ECL and UG for all treated groups as compared to control. It was concluded that the administration of NaF to female mice have harmful effects on histological changes of ovaries and uterine horns; and consequently may have a negative effects on female fertility and fecundity.

أجريت الدراسة الحالية بهدف معرفة تأثير إعطاء فلوريد الصوديوم (NaF) إلى إناث الفئران عن طريق ماء الشرب في التغييرات النسجية لكل من المبيضين وقرني الرحم في الفئران. أستخدمت في هذه التجربة إناث فئران بالغة عددها 64 أنثى تم تقسيمها إلى أربع مجاميع رئيسة (16 فأرة لكل مجموعة) وفقاً إلى جرعة فلوريد الصوديوم المأخوذة وهي مجموعة السيطرة C وكل من المعاملات T1 وT2 وT3 وتمثل هذه المجاميع التراكيز المستخدمة من مادة فلوريد الصوديوم وهي 0 و200 و400 و600 جزء لكل مليون (ppm) على التوالي. قسمت كل مجموعة من هذه المجاميع الرئيسة إلى مجموعتين فرعيتين تمثل كل واحدة مدة من مدد إعطاء فلوريد الصوديوم وهي 10 و15 أسبوعاً، وبذلك فقد أصبحت كل مجموعة فرعية تضم 8 فئران, تم فيها حساب كل من قطر المبيض وأعداد وأقطار كل من الأجسام الصفر وحويصلات كراف والحويصلات المبيضية النامية مع حساب قطر قرن الرحم وسمك الطبقة الخلوية الطلائية المبطنة لقرني الرحم وأقطار الغدد الرحمية. أثبتت نتائج الفحوصات النسجية للمبايض حصول انخفاض عالي المعنوية (P<0.01) في كل من قطر المبيض وأعداد وأقطار كل من الأجسام الصفر وحويصلات كراف وأقطار الحويصلات المبيضية النامية لكافة المعاملات T1) وT2 و(T3 مقارنة مع مجموعة السيطرة ولكلتا المدتين 10) و15 أسبوعاً(. أما الفحوصات النسجية لقرني الرحم فقد أظهرت حصول إنخفاض عالي المعنوية (P<0.01) في كل من قطر قرن الرحم وسمك الطبقة الخلوية الطلائية لقرني الرحم وأقطار الغدد الرحمية لكافة المعاملات T1) وT2 و(T3 مقارنة مع مجموعة السيطرة ولكلتا المدتين 10) و15 أسبوعاً(. نستنتج من هذه الدراسة أن إعطاء فلوريد الصوديوم لإناث الفئران يؤدي الى حصول تأثيرات سلبية في أنسجة المبايض وقرني الرحم مما يؤثر سلباً في خصوبة إناث الفئران.

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