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Article
Effect of Some Synthesized Pyrrolidines in Growth of L. infantum Promastigotes
تأثير عدد من مركبات البايروليدين Pyrrolidines المشيدة في نمو بروماستكوت اللشمانيا الأحشائية L. infantum

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Abstract

In this research, three pyrrolidine compounds (P1-P3) were synthesized and then tested for efficacy against L. infantum promastigotes in vitro.The study included preparation of some chalcones and schiff bases then the condensation of both to get the pyrrolidines and studying the effect of pyrrolidine compounds in growth, generation number and time of parasites. They determined using concentrations between (5-30) μg/ml. The effect of the compounds was found to be important to the parasite growth as the more the concentration the less the growth, generation number and increased the generation time. At the logarithmic phase, the LD50 were (10), (20) and (30)μg/ml for (P1-P3) compounds, respectively.

في بحثنا هذا تم تصنيع ثلاث مركبات من البايروليدين (P1-P3) ومن ثم اختبارها وملاحظة فعاليتها ضد بروماستكوت اللشمانيا الأحشائيةL. infantum خارج الجسم الحي.تضمنت الدراسة تحضير بعض الجالكونات مع قواعد شيف وشيدت مركبات البايروليدين من تكثيف الجالكونات مع قواعد شيف ثم اختبرت فعالية المركبات الناتجة على نمو وعدد وزمن الجيل إذ استخدمت تراكيز تراوحت ما بين (5-30) مايكرو غرام / مل وأظهرت النتائج بأن هنالك تأثير واضح على نمو الطفيليات إذ كلما زاد التركيز قل النمو وكذلك عدد الجيل فضلاً عن زيادة زمن الجيل. وتبين النتائج بان التركيز الذي يقتل 50% من الطفيليات LD50 هو (10) و (20) و (30) مايكرو غرام / مل للمركبات (P1-P3) على التوالي عند الطور اللوغاريتمي من النمو.

Keywords

Pyrrolidines --- Leishmania --- Growth.


Article
Maternal–Placental Growth Factor and the Identification of Fetuses with Placental Intrauterine Growth Restriction

Authors: Henan Dh Skheel Al Jebory --- Asmaa Zubaid Alazzawy
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2018 Volume: 17 Issue: 1 Pages: 36-41
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Objective: This study was designed to discriminate between fetal growth restriction that is placentally mediated and constitutionally smallfetuses depending on the measurement of placental growth factor (PlGF) in the maternal circulation. Study Design: This was a prospectivecase–control study. Settings: This study was conducted at the Department of Gynecology and Obstetrics at Al‑Yarmouk Teaching Hospital.Patients and Methods: The study included 100 cases (11 placental intrauterine growth restriction [IUGR] and 89 constitutionally small)with singleton pregnancies. Serum PlGF was measured by ELISA technique. Concentration less than the 5th percentile for normal pregnancywas considered a positive PlGF test. Results: A positive PlGF test was found in 10 out of the 11 placental growth restriction cases and in4 out of the 89 constitutionally small fetuses. PlGF can differentiate between IUGR due to placental dysfunction from constitutionally smallfetuses with 90.1% sensitivity and 95.5% specificity. Conclusion: PlGF may serve as a promising tool to identify placental IUGR antenatally

Keywords

Fetus --- growth --- placenta


Article
Study of growth retardation among patients with thalassemia major: correlation to iron overload

Author: Hulal Saleh Sahib
Journal: Muthanna Medical Journal مجلة المثنى الطبية ISSN: 2226146x Year: 2018 Volume: 5 Issue: 2 Pages: 77-85
Publisher: Al-Muthanna University جامعة المثنى

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Abstract

Thalassemia is an autosomal recessive blood disorder which has a life-long implication in both patients and their families. This study was performed at Al-Diwaniya maternity and children teaching hospital from the 1st of October 2016 to the 1st of January 2017. The total number of patients involved in our study were one-hundred three, all of them were diagnosed with ß – thalassemia major, were subjected to frequent blood transfusion and were on chelating agent. Both patients groups were evaluated with full history (age, gender, time of diagnosis, the rate of transfusion per year, the type and dose of the chelating agent), and were examined for their weight, height and BMI, serum ferritin was also performed for all of them. There was a significant difference in mean age and height of patients on desferal and those on exjade. The rate of transfusion was significantly greater in the group of patients treated with desferal. Serum ferritin was significantly higher in patients treated with desferal than patients treated with exjade. There was a significant correlation between gender of patients and serum ferritin in the group of patients treated with desferal, also there was a significant negative correlation between the dose of the drug and serum ferritin in those treated with exjade.


Article
Growth of InxGa1-xSb Bulk Crystals by Czochralski Technique

Authors: E. Rivent --- K. Mijama --- T. Sakagawa --- T. Kogama
Journal: Iraqi Journal of Applied Physics المجلة العراقية للفيزياء التطبيقية ISSN: 18132065 23091673 Year: 2005 Volume: 1 Issue: 4 Pages: 17-19
Publisher: iraqi society for alternative and renewable energy sources and techniques الجمعية العراقية لمصادر وتقنيات الطاقة البديلة والمستجدة

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Abstract

To grow InGaSb with larger In composition, step growth process was adapted. By increasing the In composition step by step, In0.1Ga0.9Sb single crystal of length 18 mm was grown. Intensities and the FWHM values of X-ray diffraction spectrum were, respectively, 10 times larger and one third of the value, compared with the values of the crystal grown directly from GaSb seed crystal.


Article
Suggested Technique for Creating Physical Growth Curves Charts for Anthropometric Measurements in Admixed form in a sample of children under two years of age In Diyala Governorate

Authors: Abdul Khaleq A. Al-Naqeeb --- Khalida Abdul Sattar --- Aqeel A. Noaman
Journal: nursing national Iraqi specility المجلة العراقية الوطنية للعلوم التمريضية ISSN: 18122388 Year: 2012 Volume: 25 Issue: 2 Pages: 98-107
Publisher: Baghdad University جامعة بغداد

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Abstract

Objective: This study aimed to assessing new suggested technique of Physical Growth Curves (PGC) charts in children under two years old of a non-probability sample. Methodology: A non-probability sample of size (420) children under two years selected from 12 Primary Health Care Centers in Diyala governorate during the period from 15th Nov. 2010 to 13th Mar. 2011 according to admix of a different properties together in one chart/or growth curve chart included in at least weight, Height, and Head circumference. Results: the results showed different properties that can be admix together in one chart/or growth curve chart included in at least weight, Height, and Head circumference. And to overtake the problem of the normal distribution assumption that ought to be presented with the random variables of (PGC) in applying the conventional methods. Obtaining or estimating the (min. and max.) of the standard limits as well as the trimmed mean which were accredited on their original observations which were collected from the studied field. Recommendations: Continuous to apply the suggested technique in added another physical body’s properties such as (MUAC, Trunk Length related to abdomen center).

الهدف: تهدف الدراسة إلى تقييم تقنية جديدة مقترحة لمنحنيات النمو (منحنيات الخصائص الجسمية) للأطفال تحت السنتين في عيّنة غير احتمالية.المنهجية: تم اختيار عينة بحجم (420) طفلا دون سن الثانية من العمر من بين 12 مركزاً للرعاية الصحية ألأولية في محافظة ديالى وذلك باستخدام القياسات الانثربومترية أثناء الفترة من الخامس عشر من تشرين الثّاني 2010 ولغاية الثالث عشر من آذار 2011 طبقاً لأسلوب المزج ما بين الصفات الجسمية المختلفة برسم بياني واحد لمنحنيات النمو المتضمنة على الأقل الوزن , الطول ومحيط الرأس. النتائج: أظهرت نتائج الدراسة إنه يمكن المزج ما بين الصفات الجسمية المختلفة برسم بياني واحد لمنحنيات النمو المتضمنة على الأقل الوزن , الطول ومحيط الرأس وذلك من أجل تجاوز مشكلة افتراض التوزيع الطبيعي الواجب تحققها عند تطبيق الطرائق التقليدية المتبعة لـ (منحنيات الخصائص الجسمية ).أيضا تم تقدير أو تخمّين القيم (أعلى / أدنى ) الحدود القياسية بالإضافة إلى المتوسط المشذّب الذي أستند على المشاهدات الأصلية للبيانات التي تم جمعها ميدانياً.التوصيات: توصل البحث إلى بعض التوصيات منها الاستمرار في تطبيق التقنية المقترحة في إضافة الخصائص الجسمية الأخرى مثل محيط الذراع, طول الجذع المرتبط بمركز البطن.


Article
Study of Physical Growth Pattern in Thalassemic Children And Adolescent in Hawler Thlassemia Center /Erbil City
دراسة النمو الجسمي للأطفال والمراهقين المصابين بالثلاسسيميا في مركز الثلاسيميا في هولير/اربيل

Journal: kufa Journal for Nursing sciences مجلة الكوفة لعلوم التمريض ISSN: 22234055 Year: 2014 Volume: 4 Issue: 2 Pages: 160-166
Publisher: University of Kufa جامعة الكوفة

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Abstract

Background :Thalassaemia is one of the most common genetic blood disorders in the world. Growth impairment is a common observable complication and usually found a growth retardation in those patientsObjectives: The study aimed to identify the Physical growth pattern of Thalassemic( case group) with healthy school( control group) children and adolescents in Erbil city.Methods: A study was carried out at Hawler Thalassemia Center in Erbil City during the period from the 1-2-2012- to 30-9-2012 . Fifty Thalassemic children( case group) from Hawler Thalassemia Center in Erbil City and two hundred healthy school( control group) children and adolescents were selected . A questionnaire was designed that composed of two parts to deal with physical growth pattern the data were collected by searchers to interviewed the participants in Hawler Thalassemic Center and secondary schools, for children and adolescents in Erbil city and the data were the analysis by using the (SPSS, 17 ),Results: The results found that the range of age in the study sample was between 8-11 years old ,which present in healthy school children and adolescents ( control group ) ( 46.5%), while in Thalassemic children( study group ) was ( 52.0%),the highest percentage of gender in both groups were male ( 65.5% , 58.0%) respectively revealed that there was significant differences incomparative physical growth pattern between Thalassemic and healthy children and adolescentsConclusion : The study conclude that Thalassemic children (Case group) regarding the age they have high mean score than control group (healthy child) in (sitting and standing ) height , weight and nutritional status as BMI in all age groups. Recommendation: The study recommended that Thalassemia was a important health problem in pediatric and plans need to set up to reduce the number of cases born by development of population screening programmer and awareness creating.

خلفية البحث : ثلاسيميا من أكثر الأمراض الوراثية شيوعا في العالم ومن المضاعفات التي تلاحظ المصابين هو ضعف النمو البدني لدى ألاطفال المصابين بالثلاسيمياالهدف : تهدف الدراسة للتعرف على نمط النمو البدني( الجسمي) لدى الأطفال المصابين بالثلاسيميا ومقارنتها بالأصحاء من طلبة المدارس الثانوية لمدينة اربيلالمنهجية :أجريت دراسة في مركزهولير للثلاسيميا للفترة من 2012-2-30 الى 2012-9-2012اختيرت عينة من خمسون طفل مصاب بالثلاسيميا ومائتان طالب سليم معافى من طلاب المدارس الثانوية لمدينة اربيل تم تصميم استمارة استبيان تتضمن جزئين لجمع البيانات من خلال استخدام أداة الاستبيان باعتماد تقنيات المقابلة المباشرة كوسيلة لجمع البيانات وقد تم تحليل البيانات عن طريق برنامج SPSS الإصدار 17. ألنتائج :اظهرت النتائج بوجود فرق في أنماط النمو البدني( الجسمي) لدي الأطفال المصابين بالثلاسيميا ومقارنتها بالأطفال الأصحاء من طلبة المدارس الاستنتاجات : بينت نتائج الدراسة فيما يخص العمر وعلاقته بالطول بوجد وسط حسابي عالي لدى طلبة المدارس عند الوقوف والجلوس وكذلك عند الوزن والكتلة العضلية لجميع الفئات العمرية عند مقارنتها الأطفال المصابين بالثلاسيمياالتوصيات : . اوصت الدراسة بان مرض الثلاسيميا احدى المشاكل الصحية لدى الاطفال فان التخطيط الصحي لغرض تقليل نسبة حالات الاصابة وبرامج التحري عن المرض اضافة الى التوعية الصحية للأفراد المجتمع


Article
STUDY OF SCENEDESMUS ALGAE GROWTH IN A SPLITCOLUM AIR-LIFT PHOTOBIOREACTOR
دراسة نمو طحالب Scenedesmus باستخدام مفاعل بيو ضوئي ذو الرفع الهوائيالانقسامي

Author: Amer D. Zmat Albdiri
Journal: Al-Qadisiyah Journal for Engineering Sciences مجلة القادسية للعلوم الهندسية ISSN: 19984456 Year: 2015 Volume: 8 Issue: 3 Pages: 410-421
Publisher: Al-Qadisiyah University جامعة القادسية

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Abstract

The growth of Scenedesmus algae, cultivated in a split-column airlift bioreactor under threedifferent light intensities (94, 187, 468 E /m .s 2  ) and two values of superficial gas velocities (0.3,1 cm/s), was investigated. The physical properties of the culture medium were monitored byvarious analytical methods (optical density, chlorophyll concentration). Samples were taken twice aday (10:00 AM and 5:00 PM) for cell count and optical density measurements. The dynamicgrowth rate of the algae was studied using the integrated three-state fluid dynamics modeldeveloped by Eilers and Peeters (1988). The kinetic parameters for the system under definedlight/dark cycles were evaluated. The obtained results indicate that the growth rate and chlorophyllcontent of the Scenedesmus algae directly proportional to light intensity and superficial gas velocity.

تم دراسة نمو طحالباستخدام مفاعل بيو ضوئي من نوع عمود الرفع الهوائي الانقسامي تحت Scenedesmus0.3 ). تم رصد , 1 cm/s), 94 ) وسرع غاز سطحية , 187, 468 E /m2 .s ) ظروف مختلفة من الشدة الضوئيةوتقييم الخصائص الفيزيائية للوسط باستخدام طرق تحليلية مختلفة )الكثافة الضوئية وتركيز الكلوروفيل(. تؤخذ عيناتالفحص مرتين يوميا ) 01:11 صباحا و 0:11 مساء( لأغراض قياسات الكثافة الضوئية وعد الخلايا. تم دراسة معدلباستخدام موديل ديناميكية الاطوار الثلاثة التكاملي الذي طور بواسطة الباحثين Scenedesmus النمو الحيوي لطحالبيتناسب طرديا مع الكثافة Scenedesmus اظهرت النتائج ان معدل النمو لطحالب .Eilers and Peeters (1988)الضوئية لمصدر الاضاءة وسرعة الغاز السطحية.


Article
Effect of aging on growth hormone-leptin axis in normal andobese healthy subjects

Authors: Hedef D. El-Yassin --- Zaineb A. Razak Al-Sharifi (
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2008 Volume: 50 Issue: 3 Pages: 383-390
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Growth hormone is a hormone responsible for the normal body
growth and development by stimulation protein production in muscle cells and
energy release for breakdown of fat. On the other hand leptin is a newly discovered
hormone that is mainly synthesized in adipose tissues it decreases food intake by
causing satiety and promoting energy combustion . Both aging and obesity are
associated with a reduction in growth hormone secretion. In the mean time obese
humans have increased circulating leptin.
Objective: The aim of this paper is to shed light on the contribution of these two
hormones in the mechanism of aging process in an attempt of improving this
process for a better life at old ages.
Subjects and methods: Two hundred and seventy healthy subjects aged 25-64
years old participated in this study. The subjects' were divided into four groups
according to their ages and to three groups according to their weights. Urine
analysis from each subject was carried out to exclude diabetes and renal failure.
Sera from blood samples were used to carry out certain biochemical parameters and
hormone (growth hormone and leptin).
Results: The results obtained show a decrease in the level of growth hormone with
progression of age. In the mean time there is an increase in the level of serum leptin
with the advancement of age. Aging is usually associated with adiposity. Increasing
fat with age is probably multifactorial one potential mechanism for that is reduced
leptin transport across blood-brain barrier..
Conclusion: The increase in leptin level which was observed in elderly age group
and obese group suggest that the associated decrease in growth hormone serum
level is related to obesity in general and in particular to the aging process.

Keywords

growth hormone --- leptin --- obesity --- aging.


Article
Study of the growth and puberty in Iraqi children with nephrotic syndrome

Authors: Najla I. Ayoub --- Huda M. Khalaf --- Sabeeha M. Al-Mefraji
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2012 Volume: 11 Issue: 1 Pages: 85-89
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: Nephrotic syndrome is a chronic disease with frequent relapses and the accumulative dose of steroid play an important role in developing growth retardation.Aims: To detect the degree of growth retardation in long standing nephrotic syndrome and frequent relapsing nephrotic syndrome, and to identify the effect of nephrotic syndrome and steroid therapy on puberty.Patient and methods: A cross sectional study conducted in Child Central Teaching Hospital from the first of January to first of July 2008, on 108 patients with steroid responding nephrotic syndrome, 60 of them were males and 48 were females. All had anthropometric measurement of height and the assessment depend on Tanner growth centile for age and sex, so as the puberty staging according to Tanner staging. The ranges of the patients ages were 2-17y and the mean age was 11.5+4 y. 59.25% (64) were having steroid toxicity; no patient was on cytotoxic drug.Results: The results were shown that 52/ 108 (48.18%) of the patients have got growth retardation (2SD below the mean) Fifty of the patients were at pubertal age, 30 were males and 20 were females. 39 patients had delayed puberty (78%), 36 patients with delayed puberty had steroid toxicity (94.73%). There is a significant relationship between frequency of relapses, duration of illness and steroid toxicity with incidence of delayed puberty and growth retardation.Conclusions: There is a significant correlation between the growth retardation and the development of steroid toxicity. With frequent relapses and long standing nephrosis, there is a chance to develop growth retardation. Delayed puberty is more with steroid toxicity and it is more in males than females.


Article
ANTIMICROBIAL INFLUNCES OF ESSENTIAL OIL EXTRACTED FROM SOME PLANTS FORMULATIONS ON PATHOGENIC BACTERIA
التأثيرات ضد الميكروبية للزيوت المستخلصة من بعض النبات وتأثيرها على بعض البكتريا المرضية

Author: Rana, A. Faaz* Hazim, S. Jabar رنا عدنان فائز* حازم سعد جبار**
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2007 Volume: 6 Issue: 2 Pages: 94-110
Publisher: Basrah University جامعة البصرة

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Abstract

Antimicrobial disk susceptibility tests serve as standard assays for measuring the activity of compounds against pathogenic bacteria. In the current study, some plant-derived proprietary essential oil blends (Olea europaea , Pimpinella anisum L. , Coriandrum sativum , Matricaria chamomilla L. , Borago officinalis , Cimum basilicum L. , Cuminum cyminum , Thymus vulgaris thymol , Menta xpiperita L. , Rosmarinas officinalis comphora) were tested for their antibacterial activity against five common strains of pathogenic bacteria using disk susceptibility tests. A formulation intended for topical use (Essential Oil Formulation 1) (EOF1) inhibited the growth of Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus as evidenced by zone inhibition diameter measurements when compared to those reported for standard antibiotics. EOF 1 exhibited no activity against Proteus vulgaris and Staphylococcus epidermidis. The second formulation (Essential Oil Formulation 2) (EOF2), intended for inhalation use, inhibited the growth of all five test bacteria strains with zone inhibition diameters two to three times greater than those reported for standard antibiotics. The growth of all five bacteria strains was inhibited when a cotton swab impregnated with EOF 2 was suspended above the bacterial lawn, indicating a true vapor or fume effect by this formulation.

ان اختبارات الاقراص ضد الجراثيم تعمل كتجارب قياسية لقياس فعالية بعض المركبات ضد البكتريا المرضية. في الدراسة الحالية تم استخلاص الزيوت من بعض النباتات (الزيتون ، اليانسون ، الكزبرة ، بابونك ، الريحان ، كمون ، زعتر البساتين ، نعناع فلفلي و زهرة اكليل الجبل) لاختبار فعاليتهما ضد البكتريا وقد استخدمت خمس انواع من البكتريا المرضية باستخدام أقراص تجارب خصصت لهذا الغرض الطريقة التي تستخدم للاستعمال الموضعي (EOF 1) وهي تستخدم لتثبيط نمو Escherichia coli ، Klebsiella pneumoniae، وStaphylococcus aureus ويستدل على منطقة التثبيط بواسطة قطر منطقة الثبيط حيث تقاس عندما تقارن مع تلك الاقراص المضادات الحيوية القياسية. (EOF 1) توضح بأنه لا يوجد فعالية ضد Staphylococcus epidermidis و Proteus vulgaris . الطريقة الثانية التي استخدمت هي (EOF 2) وهنا تم استخدام الاستنشاق حيث يتم توضيح تثبيط خمسة انواع جميعها من البكتريا بمنطقة تثبيط أقطارها اثنان إلى ثلاثة مرات وهي اكبر من تلك التي تم الاعتماد عليها في أقراص المضادات الحيوية. أن نمو الخمسة أنواع من البكتريا جميعها يتثبط عندما يتم استخدام مسحات القطن التي لحقت بطريقة (EOF 2) وهذا يوضح وجود نمو بكتيري وهذا يشير على وجود بخار أو دخان واضح عند استخدام هذه الطريقة.

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