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Article
Gingival Health and Alveolar Bone Loss Among Iraqi Overweight Primary School - Age Pupils (Radiographic Study)

Author: Sanaa J. AL-Qasab
Journal: Tikrit Journal for Dental Sciences مجلة تكريت لعلوم طب الاسنان ISSN: 20731213 Year: 2014 Volume: 3 Issue: 1 Pages: 101-106
Publisher: Tikrit University جامعة تكريت

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Abstract

Many studies have found a strong association between obesity and various clinical and radiographical aspects of periodontal disease, most of these studies were directed toward adult age group only, while younger ages were omitted. To provide radiographic data about the effect of overweight on periodontal health status among Iraqi primary school-age pupils.The sample of this research was consist of 90 pupils of both gender (45 girls and 45 boys) with age range (6-12)years. All were examined clinically for bleeding on probing (BOP) and radiographically for alveolar bone loss (ABL). According to their percentile ranking the pupils in each gender group were divided into 3 subgroups (healthy weight, at risk of overweight and overweight). each subgroup was consist of (15 child). Greater mean values for BOP index were recorded for pupils in overweight group (0.8 for girls and 0.66 for boys) in comparison to those in healthy (0.26 for girls and 0.46 for boys) and at risk (0.4 for girls and 0.46 for boys), also greater mean values for ABL radiographically were recorded for pupils in overweight groups (1.53 mm for girls and 1.66 mm for boys) in comparison to those healthy (1.00 mm for girls and 0.8 mm for boys) and at risk (1.06 mm for girls and 1.46 mm for boys). According to paired t- test most of these differences were found to be statistically significant. On the other hand, No significant difference were recorded between different study groups on gender basis. There is a clear relation between obesity and periodontal health on both clinical and radiographical examinations.

Keywords

obesity --- bmi --- bop --- abl.


Article
HLA Typing in Iraqi Patients with Obesity and Primary Osteoarthritis.

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Abstract

Background: Osteoarthritis (OA) is a degenerative joint disease. It is one of the major causes of disability in developed and developing countries. Human leukocyte antigen (HLA) as part of immune system has a role in the disease process.Objectives: To investigate whether there is an association between HLA class II-DRB and OA.Methods: A case control study with 26 patients with osteoarthritis and 22 apparently healthy obese control persons matching in ethnicity were enrolled in this study during the period between October 2012 till March 2013. Direct interview was done with each patient and HLA typing was done by molecular method using Sequence Specific Primer (PCR-SSP) method using One Lambda Kit-USA. Results: The results showed that females were more affected than males with disease when compared with control. Odds ratio were used to test level of significance. This study showed that HLA DR4 (DRB1*04), DR2 (DRB1*15 and DRB1*16), DR9 (DRB1*09), DR10 (DRB1*10, DRB5*, DRB4* and DRB3*) (odds ratio: 14.26, 9, 9, 9, 14.26, 9.5 and 4.5) respectively are associated with OA.Conclusions: OA is highly associated with HLA class II DR4 (DRB1*04), DR2 (DRB1*15, DRB1*16), DR9 (DRB1*09), and DR10 (DRB1*10).DR5 (DRB1*05) is not associated with OA.


Article
Leptin and Insulin Resistance in Obese Children

Author: Noor T. Tahir Ph.D*, Hind S. Ahmed Ph.D**, ALmottesembellah A. Gaiz M.Sc ***
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2014 Volume: 10 Issue: 2 Pages: 36-40
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Insulin resistance (IR) is the primary metabolic disorder associated with obesity. Obesity is a growing worldwide health problem affecting both adults and children. Objectives: To determine the association between leptin and IR, and to identify the ratio of fasting glucose/leptin (G/L) and insulin/leptin (I/L) as a new simple method for the detection of IR in obese children.Methods: This study was done in the National DiabeticCenter/ AL-Mustansiriya University during the period fromMay 2013 until the end of October 2013. Fasting bloodglucose (FBG), serum insulin, leptin, and lipid profile weremeasured in 52 obese children (24 children with IR and 28without IR); their age range was (5-15) years, they werecompared with 38 healthy children as a control group.Results: Means of FBG, insulin, leptin, total cholesterol(TC), triacylglycerol (TAG), low density lipoproteincholesterol (LDL-C), and non high density lipoproteincholesterol (non HDL-C) were significantly increased inobese children with IR as compared in children without IR,(P<0.05), while there was a significant decrease in serumlevel of high density lipoprotein cholesterol (HDL-C) inobese children with IR when compared with obese childrenwithout IR, (P=0.001). There was a decrease in the ratio ofG/L and an increase in the ratio of I/L in obese children withIR, but it was not significant. A significant positivecorrelation was found between serum leptin verse bodymass index (BMI), FBG, insulin, homeostasis modelassessment for insulin resistance (HOMA-IR), I/L ratio, TC,TAG, LDL-C, and non HDL-C, while a significant negativecorrelation was found between serum leptin and HDL-C inobese children with IR.Conclusions: The present results showed that serum leptinis correlated with BMI, FBG, insulin, HOMA-IR, I/L ratio, TC,TAG, LDL-C, and non HDL-C in obese children with IR. TheG/L ratio can be used in addition to me /L ratio, and HOMAto accurately assess IR in obese children

Keywords

Obesity --- insulin resistance --- Leptin


Article
The relationship between obesity and plasma level of factor V and fibrinogen

Authors: Haithem A. Al-Rubaie هيثم احمد الربيعي --- Jaffar N. Alalsaidissa جعفر نوري --- Halla A. Jabber هاله عبد الصمد جابر
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2017 Volume: 59 Issue: 1 Pages: 53-59
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Obesity is a medical condition in which excess body fat has accumulated to the extent that it has an adverse effect on health.. It measured by BMI (body mass index), obesity is considered when the BMI is ≥ 30 kg/m2.It increases the risk of coronary heart disease, Diabetes Mellitus and Cancer. Chronic inflammation and impaired fibrinolysis in obesity may induce thrombosis.Aim of study: assess the effect of BMI (body mass index) on plasma level of Factor V and fibrinogen in obese and normal weight subjects.Methods:This study was started on December 2015 and completed on June 2016, and included 51 obese attended alyarmouk Teaching Hospital. As well 25 non-obese subjects, were recruited as a control, age range from18to 50 years old .The hemostatic parameters done for them included the prothrombin time, activated partial thromboplastin time, FV activity, fibrinogen level, and platelet count.Results:There were insignificant difference in the means of prothrombine time (PT),activated partial thromboplastine time(aPTT), Factor V activity( FV) and Platelet count(PLT)of obese group compared to control group with P value (0.63, 0.902, 0.44, 0.484) respectively. There was significant difference in the mean of fibrinogen of obese group compared to control group with P value (0.006).The correlation between BMI and (PT, PLT, FV and fibrinogen)in obese and control study groups were statistically insignificant with (P > 0.05) , but a significant positive correlation between BMI and PTT in obese group was found with (P=0.037). There was a significant negative correlation between FV and PT in obese and control groups (P =0.001).There was insignificant positive correlation between fibrinogen and PT in obese and control groups (P > 0.05).Conclusions: Significant difference in the mean of plasma level of fibrinogen concentration between obese group and normal weight group was found. Insignificant difference in the means of PT, aPTT, platelet count and FV activity between obese group and normal weight group were found.Keywords: obesity, FV, fibrinogen.

Keywords

Keywords: obesity --- FV --- fibrinogen.


Article
Risk of Obesity on Woman Health in Baghdad City
مخاطر السمنة وتاثيرها على صحة المرأة في مدينة بغداد

Author: Faeza A. Fakhry فائزة فخري
Journal: Iraqi Journal of Science المجلة العراقية للعلوم ISSN: 00672904/23121637 Year: 2017 Volume: 58 Issue: 4B Pages: 2041-2050
Publisher: Baghdad University جامعة بغداد

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Abstract

Maternal obesity is linked rates of high-risk obstetrical conditions such as diabetes and hypertension with higher rates of cesarean section. Pregnancy outcomes are negatively affected by maternal obesity (increased risk of neonatal mortality and malformations) . The research aims to show the effect of obesity of woman on physical and metabolisms status.

الأم البدينة تتعرض إلى مخاطر عالية منها إرتفاع معدلات السكر والضغط مما يؤدي إلى زيادة نسبة العمليات القيصرية . نتائج الحمل تكون سلبية على الأم البدينة ( زيادة معدل الوفيات والتشوهات الخلقية الجنينية ) .

Keywords

Risk --- Obesity --- Woman health


Article
Extent of Overweight and Obesity among Children Aged (6-60) months in Al-Nasiriya at 2015-2016
مدى زيادة الوزن والسمنة بين الأطفال الذين تتراوح أعمارهم بين (6-60) شهرا في الناصرية في 2015-2016

Author: Dr. Ghada Mansoor Abood Al-Asadi الدكتورة غادة منصور عبود
Journal: Thi-Qar Medical Journal مجلة ذي قار الطبية ISSN: 19929218 Year: 2018 Volume: 15 Issue: 1 Pages: 58-71
Publisher: Thi-Qar University جامعة ذي قار

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Abstract

Background: The problem of obesity and overweight in children has been increased globally. Recently, the obesity prevalence rate reached an alarming level in both developed and developing countries. Objectives: This study aims to determine the extent of overweight and obesity among infants and children aged 6-60 months in the center of AL-Nasiriya governorate and their relationship with different socio-demographic and lifestyle factors.Methods: A cross-sectional study was carried out on 225 infants and children aged 6-60 months selected from children who have consulting primary health centers that randomly selected in AL-Nasiriya city during the period from October 2015 till the end of February 2016. BMI and Z-score was measured and compared to standard tables. Data on socio-demographic factors and dietary pattern was obtained by questionnaire. Results: The proportion of overweight was 11.1% and for obesity 7.6% according to weight for height Z-score for all children. For children >24months, we found that 10.8% were overweight and 8.8% were obese by using BMI. In this study, there is a significant positive association between father's education and dairy products intake with overweight and obesity.Conclusion: The prevalence of overweight and obesity among infants and children aged 6-60 months in Al- Nasiriya was high. It is positively associated with dairy products intake and father education had a positive relationship with obesity.

Keywords

Extent --- Overweight --- Obesity --- children.


Article
4.REPRODUCTIVE HORMONAL ASSAY OF A SAMPLE OF IRAQI OBESE MALES

Authors: Imad M. Abdul-Rahman عماد محمود عبد الرحمن --- Atheer J. Abdul-Ameer اثير جواد عبد الامير
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2019 Volume: 17 Issue: 2 Pages: 114-119
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background:The World Health Organization considered obesity as a medical condition that may lead to reduced life expectancy and/or increased health problems. While much of the focus on the impairments caused by obesity is on somatic health, recent data suggest that reproductive health may also be impacted.Objective:To quantify the relation between obesity and the reproductive hormones.Methods:This cross-sectional study was carried out at nutrition clinic in three teaching hospitals and one obesity clinic in a medical college in Baghdad. The body mass index (BMI) calculation, blood sugar, serum cholesterol, triglyceride, testosterone, prolactin, follicular stimulating hormone (FSH), and luteinizing hormone (LH) were measured.Results:Ninety-five adult obese males participated in this study. Serum testosterone had significant negative correlation with BMI, weight, serum cholesterol, and serum triglyceride while serum LH had significant positive correlation with BMI (p value was 0.013), weight (p value was 0.027), and serum triglyceride (p value was 0.049).Conclusion:Male obesity has significant effect on serum level of testosterone and LH.Keywords:Obesity, reproductive hormonesCitation:Abdul-Rahman IM., Abdul-Ameer AJ. Reproductive hormonal assay of a sample of Iraqi obese males. Iraqi JMS. 2019; 17(2): 114-119. doi: 10.22578/IJMS.17.2.4


Article
Relationship of Obesity to Serum Ferritin, Lipid Profile, uric acid and urea at Obesity Medical Center in Iraq

Authors: Zaizafoon N. Nasif --- Emad M. Eltayef --- Nasser M. Al-Janabi --- Ali N. Niseaf
Journal: Al-Mustansiriyah Journal of Science مجلة علوم المستنصرية ISSN: 1814635X Year: 2018 Volume: 29 Issue: 1 Pages: 87-96
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Obesity is a hyper assembly of energy in the form of adipose tissues which has worse effects on health. The major factors of obesity epidemic are : heavy mails which are rich in lipids, carbohydrates resulting in over weight and eventually obesity, decrease in physical activity that lead to defect in calories conception. In health care facilities ferritin assay is used as a screening test to detect iron deficiency; however, its reliability in obesity has been questioned. The aim of present study was to assess and compare the incidence of obesity, hyperfer-ritinemia, hyperlipidemia and hypouricemia among middle aged hypertensive patients in the local setting as well as, examined ferritin concentrations and other classical indices in obese males and females .This limited population study was conducted at Obesity Medical Center at Al-Kindy Teaching Hospital, Baghdad, Iraq from January to march 2016. One hindered and eight patients were enrolled in this study plus to participate of 61 subjects as healthy control. On the basis of body mass index (BMI), 169 participants were divided into two groups: BMI ≥ 18.5–25 kg/m2 non obese (control), BMI ≥ 30 kg/m2 obese subjects. The main demographic features data of the study population appears that, systolic blood pressure and diastolic blood pressure were raised significantly in obese patients (P<0.05) compared with control. Serum hemoglobin level was decreased significantly in obese male when compared with the non-obese group and no difference in female group was observed. In addition, the levels of lipid profile and other studied parameters according to gender showed the following results: A sig-nificant elevation in TG, LDL, VLDL, glucose, ferritin in obese (for both genders) compared with the non-obese group. While a significant decrease was noticed in HDL-c, uric acid and urea level in obsess group compared with the non-obese group in both genders. The compari-son results between obese males and females concluded that a significant elevation in BMI with a significant decrease in VLDL and ferritin levels in obese females compared with obese males. Present study includes examined all types of correlation between parameters .In obese patients (n=108), stepwise linear regression analysis showed that, serum ferritin levels were independently correlated with LDL, VLDL levels and age, (P< 0.001).

تعرف السمنة بانها تجمعً عالي مِنْ الطاقةِ على شكل أنسجة دهنية والتي لَها تأثيراتُ سيئة على الصحة العامة. . إنّ العوامل الرئيسية للسمنةِ تتمثل ب: الوجبات الثقيلة الغنية بالدهون, تناول الكثير من السكريات, نقصان في النشاطِ الطبيعي والذي يؤدي لخزن المزيد من السعرات الحرارية .عادة يعتبر اختبار الفرتيين تحليل معتمد للكشف عن نقص الحديد في الجسم ولكن علاقة الفرتيين بالسمنة هي مصدر مثير للتساؤلات لدى الباحثيين . الهدف من الدراسة الحالية تقدير ومقارنة الاصابة بالسمنة, ارتفاع مستوى الفرتيين,ارتفاع مستوى الدهون وانخفاض مستوى اليوريا بين مرضى ارتفاع ضغط الدم بمنتصف الاعمارو كذلك قياس تركيز الفرتيين ومتغيرات كلاسيكية اخرى بين الذكور والاناث البدناء .اجريت الدراسة في مركز السمنة الطبي في مستشفى الكندي التعليمي في بغداد للفترة مِنْ يناير/كانون الثّاني إلى مارس/آذارِ 2016وذلك باخذ عينات من 109 مريض بالسمنة و61 كمجموعة سيطرة (اناس اصحاء).وتم اعتماد مقياس التصنيف العالمي BMI لتقسيم العينات حيث صنف الذين يمتلكو≥ 30 kg/m2 BMI مجموعة السمنة وممن يمتلكون BMI ≥ 18.5–25 kg/m2 مجموعة االسيطرة. اما البيانات السكّانيةِ الرئيسيةِ لمجموعة الدراسةَ تَظْهرُ بأنّ، ضغط الدمّ الإنقباضي وضغط الدمّ الانبساطي يرتفعان بشكل ملحوظ في مجاميع البدناءعن مجموعة السيطرة (بي <0.05)وملاحظة الانخفاض في مستوى الهيمكلوبين لدى الذكور البدناء مقارنة مع السيطرة وعدم التغير في مستواه لدى الاناث .اما مستوى الدهون والمتغيرات المقاسة الاخرى فقد اعطت النتائج التالية: ارتفاع معنوي في مستويات الفرتين, السكر, Tg, LDL,VLDLفي البدناء من كلا الجنسيين مقارنة مع السيطرة .في حين ان هناك انخفاض ملحوظ في مستويات اليوريا, اليورك اسيد, HDL-c في مجموعة البدناء مقارنة بغير البدناء ولكلا الجنسيين .اما الدراسة المقارنة بين الذكور والاناث البدناء فقد اظهرت زيادة معنوية فيBMI ونقصان معنوي في مستوى الفرتيين وVLDL لدى الاناث البدينات مقارنة بالذكورالبدناء .وتضمنت الدراسة فحص معامل الارتباط بين جميع المتغيرات وفحص معامل الانحدار المعياري والذي اظهر الارتباط المعنوي بين الفرتين وكل من العمر ومستوى LDL,VLDL.


Article
Effect of leptin level in non insulin dependant (type 2) obese diabetic subjects

Authors: Othman G. Othman --- Maysaa J. Majeed
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2009 Volume: 51 Issue: 1 Pages: 76-80
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Determine how do obesity and type2 diabetes intertwined? and what it takes to turn an obese person into a person with diabetes. That link may help to understand why some obese people never develop diabetes while many others do.Serum sugar level was used as indicator of insulin level; leptin level was used as indicator of leptin resistance.A total of 50 obese subjects were involved in this study, 25 obese subject (BMI >30) had diabetes mellitus type 2(no insulin dependant), selected from Baghdad teaching Hospital in Baghdad /Iraq. The remaining 25 obese (BMI >30) were normal healthy individuals.Patients and Methods: ELSA technique was used for the measurement of serum leptin. Blood sugar was determined by using colorimetric method. Data were expressed as mean ± SD results and were evaluated using the student t-test for paired data. Conventional methods were used for the correlation and regression analyses.Results: Obtained results showed that the level of serum leptin in healthy obese subjects were significantly lower than that of obese diabetes subjects. , serum sugar in non diabetic obese subjects was significantly lower than obese diabetes type2 subjects.Serum leptin correlated negatively with level of serum sugar at the same time had a positive correlation with BMI in non diabetic obese group whereas level of serum leptin correlated positively with each of BMI and serum sugar in diabetic type2 group. All results are thoroughly discussed in the text.Conclusion: The present study indicates the possibility of future development of a new class of anti diabetic agents that act centrally and independent of insulin action.


Article
Effect of aging on growth hormone-leptin axis in normal andobese healthy subjects

Authors: Hedef D. El-Yassin --- Zaineb A. Razak Al-Sharifi (
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2008 Volume: 50 Issue: 3 Pages: 383-390
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Growth hormone is a hormone responsible for the normal body
growth and development by stimulation protein production in muscle cells and
energy release for breakdown of fat. On the other hand leptin is a newly discovered
hormone that is mainly synthesized in adipose tissues it decreases food intake by
causing satiety and promoting energy combustion . Both aging and obesity are
associated with a reduction in growth hormone secretion. In the mean time obese
humans have increased circulating leptin.
Objective: The aim of this paper is to shed light on the contribution of these two
hormones in the mechanism of aging process in an attempt of improving this
process for a better life at old ages.
Subjects and methods: Two hundred and seventy healthy subjects aged 25-64
years old participated in this study. The subjects' were divided into four groups
according to their ages and to three groups according to their weights. Urine
analysis from each subject was carried out to exclude diabetes and renal failure.
Sera from blood samples were used to carry out certain biochemical parameters and
hormone (growth hormone and leptin).
Results: The results obtained show a decrease in the level of growth hormone with
progression of age. In the mean time there is an increase in the level of serum leptin
with the advancement of age. Aging is usually associated with adiposity. Increasing
fat with age is probably multifactorial one potential mechanism for that is reduced
leptin transport across blood-brain barrier..
Conclusion: The increase in leptin level which was observed in elderly age group
and obese group suggest that the associated decrease in growth hormone serum
level is related to obesity in general and in particular to the aging process.

Keywords

growth hormone --- leptin --- obesity --- aging.

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