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Article
INVESTIGATIONAL STUDY TO CHANGES OCCUR IN CONCENTRATION OF BLOOD SERUM PROTEIN DURING PREGNANCY IN IRAQI COW
دراسة استقصائية للتغيرات الحاصلة في تركيز بروتينات مصل الدم خلال فترة الحمل في الأبقار العراقية

Author: Rashad Fadhil Ghadhban. رشاد فاضل غضبان
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2008 Volume: 7 Issue: 1 Pages: 51-57
Publisher: Basrah University جامعة البصرة

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Abstract

A study was conducted on (35) healthy Frisian cow aged (2-4) years and were grown in farms in Al-zubair region, in Basrah city This study was performed to find the effect of pregnancy on blood serum protein concentration (Total protein, Albumin, Globulin, Globulin fractions (α, β, γ).The result revealed there was significant elevation (P<0.01) in concentration of Total protein, Albumin, Globulin, α, γ, Globulin between non pregnant and pregnant animal in 8th month. And there was no significant change occur on β, Globulin concentration.¬¬When compared the result between the 8th and 9th month of pregnant the result revealed very significant decrease (P<0.01) in the concentration of Globulin, α, γ, Globulin and significant decrease (P<0.05) in the concentration of Total protein, while significant increase in Albumin concentration, in the 9th month of pregnant, and there was no significant change in β, Globulin concentration.

أجريت الدراسة على 35 بقرة بعمر 2-4 سنة نوع فريزيان مضربة ، خالية من الأمراض سريريا ومتواجدة في عدد من مزارع قضاء الزبير- مدينة البصرة لمعرفة تأثير الحمل في تركيز بروتينات مصل الدم البروتين الكلي (Total protein )، الألبومين (Albumin)، الكلوبيولين (Globulin) وأجزاءه (ألفا وبيتا وكاما- كلوبيولين) .أظهرت النتائج ارتفاعا معنويا(P<0.01 ) في تركيز كل من البروتين الكلي والألبومين والكلوبيولين وأجزاءه (ألفا وبيتا وكاما- كلوبيولين) بين الحيوانات غير الحوامل و الحوامل إلى الشهر الثامن من الحمل، بينما تركيز البيتا كلوبيولين لم تظهر النتائج أي تغيير معنوي فيه.أظهرت نتائج مقارنة تركيز البروتين الكلي والألبومين والكلوبيولين وأجزاءه خلال الشهر الثامن والتاسع من الحمل وجود انخفاض معنوي(P<0.01) في تركيز الكلوبيولين وألفا والكاما كلوبيولين وانخفاض معنوي(P<0.05)في تركيز البروتين الكلي ،بينما كان ارتفاع معنوي(P<0.05) في تركيز الألبومين في الشهر التاسع مقارنة مع الشهر الثامن من الحمل ولم تظهر النتائج أي اختلاف في تركيز البيتا كلوبيولين

Keywords

: Globulin --- Serum --- Protein


Article
PATHOLOGICAL CHANGES OF ACUTE TOXICITY INDUCED BY ORAL ADMINISTRATION OF MALATHION IN PIGEONS
التغيرات المرضية للتسمم الحاد الناتج عن تجريع الحمام بالمالاثيون

Author: Harith, A.N. حارث عبد الله نجم
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2009 Volume: 8 Issue: 2 Pages: 65-77
Publisher: Basrah University جامعة البصرة

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Abstract

The objective of the present study was to investigate the pathological changes of the acute toxicity of Malathion as organophosphorus insecticide in wild pigeons (Rock dove). Liver enzyme Alanine Transaminase (ALT) in the serum of treated pigeons was measured. The maximum tolerated dose of malathion was 3.525mg / kg B.W. However, when the maximum tolerated dose of the malathion was given to group A, two out of eight pigeons died within two hours after treatment .The insecticide caused clinical signs appeared within two hours before death, they included salivation, lacrimation , gasping, frequent defecation, drooping of wings, tremors, convulsion and recumbancy. Also the histopathological changes of the acute toxicity of present study included vacculation of nerve fibers in the spinal cord and sciatic nerve, meningitis associated with lymphocytic infiltration in the brain, myocardial fibrosis, aggregation of lymphocytes and hepatic septal fibrosis. Cortical fibrosis with inflammatory cells, regenerating renal cortical tubules and dilated cortical tubules were also seen. Compared to control values the exposure to insecticide caused increase of the ALT level in the serum for treated pigeons, and this increment was significant. In conclusion Malathion insecticide administered orally at maximum tolerated dose induced clinical signs of poisoning, pathological changes in different organs of pigeons and increased the ALT value.

إن هدف الدراسة الحالية هو معرفة التأثير المرضي للمبيد الفسفوري المالاثيون في الحمام، وقياس مستوى إنزيم الالينين ترانس امينيز في مصل دم الحمام المعامل. الجرعة الأعلى التي يتحملها الطير كانت 3.525 ملغم/ كغم من وزن الجسم. أعطيت هذه الجرعة إلى مجموعة A اثنان من ثمان حمامات ماتت خلال ساعتين من المعاملة. واظهر الحمام قبل الموت علامات التسمم بعد ساعتين من التجريع والتي تتضمن، إفرازات لعابية، تدمع، صعوبة تنفس، التبرز المتكرر، تهدل الأجنحة، رعشة، تشنج واضطجاع. بينت النتائج تغيرات مرضية تتضمن تنكس الألياف العصبية للحبل ألشوكي والعصب ألوركي، التهاب الدماغ واتشاح الخلايا اللمفية، تليف عضلة القلب، تنكس حويجزي، تجمع خلايا اللمفية في الكبد، ، تليف قشرة الكلية مع تواجد خلايا التهابية,تجدد الخلايا المبطنة للأنابيب الكلوية وتوسع الأنابيب الكلوية في منطقة القشرة .كما سبب المبيد الفسفوري زيادة في مستوى إنزيم الالينين ترانس امينيز وهذه الزيادة كانت معنوية مقارنة مع مجموعة السيطرة. ان المبيد الفسفوري الحشري المعطى فمويا بالجرعة الأعلى التي يتحملها الطير يظهر العلامات السريرية للتسمم، تغيرات مرضية في عدد من الأعضاء التي تم فحصها في الحمام المعاملة بهذه المادة. و زيادة في مستوى إنزيم الالينين ترانس امينيز

Keywords

Pigeon --- Insecticide --- Serum.


Article
Effect of Storage on Some Blood and Serum Constituents
تأثير الخزن على بعض مكونات الدم ومصل الدم

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Abstract

To examine the possibility that the storage of blood or serum can cause an effect on some blood parameters, the concentrations of total cholesterol (TC), urea, uric acid, Sodium (Na+), potassium (K+) and chloride (Cl-) were determined in the blood or serum samples, stored at 4oC, during 0, 2, 4, 6 hours as well as at 1, 2 and 6 days.

لغرض فحص احتمالية خزن نموذج الدم او مصل الدم من ان يسبب تغيراً ببعض مكونات الدم ، تم تعين مستويات الكلولسترول الكلي ، جوهر البول ، حامض اليوريك ، الصوديوم ، البوتاسيوم و الكلوريد في نموذج بلازما الدم و مصل الدم خلال فترة خزن لمدة 2 ، 4 ، 6 ساعة و 1 ، 2 و 6 يوم . تم اختيار 56 شخصاً (35 من الذكور و 21 من الاناث) معدل اعمارهم 21 سنة (تتراوح من 19 – 23 سنة) . كانوا من غير المدخنين والذين هم ظاهرياً اصحاء وان معدل اوزانهم ضمن الحدود الطبيعية والذين لايعانون من مشاكل صحية ومن غير المتعاطين للادوية خلال الاسبوع الماضي من الدراسة، وقد تم قياس مستويات الكولسترول الكلي ، جوهر البول ، حامض اليوريك ، الصوديوم ، البوتاسيوم والكلوريد لهم في الاوقات صفر ، 2 ، 4 و 6 ساعة و 1 ، 2 ، 6 يوم . ان مضي الوقت او الخزن للدم قد اثر على تراكيز بعض مكونات الدم . ففي نموذج مصل الدم وخلال فترة الخزن البالغة 6 يوم . لم يؤثر الخزن على تراكيز الكولسترول الكلي ، الصوديوم ، البوتاسيوم والكلوريد وبقيت تراكيزهم تقريباً ثابتة بينما اثر الخزن على تراكيز جوهر البول وحامض اليوريك وسبب انخفاضاً غير معنوياً .

Keywords

Storage --- blood --- serum --- constituents.


Article
Early Evaluation of Serum Albumin Level in Pediatric Burned Patients

Authors: Kadhum J. A. Shaba'a --- Hasan Th. Ghanem --- Suhad R. Majeed
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2009 Volume: 2 no.8, 9 Issue: 5 Pages: 681-686
Publisher: Kerbala University جامعة كربلاء

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Abstract

background: Burn patients are unique in that not only do they reduce albuminsynthesis in response to trauma, but also they experience accelerated albuminlosses into their wound dressings and soft tissue.Methods: Serum albumin has been determined in 26 children with age rangedbetween (l-14) years and with total body surface area of burn (11-60%) during theirinitial few weeks of care. Their serum albumin levels were estimated at second day,seventh day and fourteenth day after burn. Intravenous albumin was administered byinfusion of 1-2 g/kg/d when plasma Albumin fell bellow 2 g/100ml. or bellows 2.5g/100ml in the presence of enteral feeding intolerance or pulmonary dysfunction,their further results were excluded.Results: The mean plasma Albumin was 3.062 g/100ml) at day 2 , 2.952 g/100mlat day 7 and 2.45 g/100ml at day 14 . The relationship between the surface area ofburn and albumin concentration was not significant, (r = - 0.1111406). The valueof albumin was found to be 0.752 g/dl under the normal average value (p< 0.005).Conclusion: Hypoalbuminemia is usual in pediatric burned patients especiallyafter 7 -14 day of the accident, the period of high risk of septic complications.Keywords: Serum albumin, Hypoalbuminemia, Burn


Article
SERO - EPIDEMIOLOGY OF SHEEP BRUCELLOSIS IN BAGHDAD
دراسة وبائية مصلية عن البروسلا في الاغنام

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Abstract

A total of 531 serum samples were subjected to Rose Bengal test (RBT) , serumagglutination test (SAT) and indirect flurocent antibody test (IFAT) and ELISA.The incidence of brucellosis was found to be 55.76%, 47.64% ,55.76% , and 58.70%,on basis ofRBT.SAT.lFATand ELISA respectively . The agreement between the RBT and. SAT was 85.47% and between RBT and IFAT was 100% ingiving apositive result. lncase ofELISA the positive results was higher and we recommended using it as the defenitive test fordetection of brucellosis

Keywords

Serum --- lFAT --- Brucellosis


Article
Zinc Status In Children With Bronchial Asthma

Authors: Tiran Abdulsttar Kakarash --- Abbas Al-Rabaty
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2012 Volume: 11 Issue: supplement Pages: 698-703
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT: BACKGROUND: Bronchial asthma is a chronic inflammatory disease of the respiratory tract. The rise in asthma and allergic disease among children is a matter of worldwide concern. Many authors have argued that the changes in diet may have been an important determinant of increased susceptibility to asthma. Free radicals have been proposed to be responsible for the pathogenesis of many diseases because of their harmful effects on the cells and tissues. The enzymes responsible for antioxidant defense have trace elements like zinc. OBJECTIVE: To evaluate the relation between bronchial asthma and zinc serum level, and the relation between serum zinc level and the duration and severity of asthma. PATIENTS AND METHODS: A Case control study was conducted at Raparin pediatric teaching hospital in Erbil city. Fifty children from ages 1 to 12 years of both sexes who were known cases of asthma and had visited Raparin teaching hospital were enrolled in this study, another sample of 50 healthy children matched for age and gender, without history of chronic disease were taken as a control group. The zinc concentrations in serum were measured in both cases and controls. RESULTS: This study shows that there were significant difference in the values of serum zinc between asthmatic and control group (p<0,01 and p<0,01 respectively).The mean concentrations of zinc are lower in asthmatic children(70.02μg/dl) in comparison to controls(84.04μg/dl).CONCLUSION: Children with bronchial asthma have a great risk of zinc deficiency, and serum zinc level has significant relation to the severity of asthma and the use of steroid

Keywords

asthma --- serum zinc


Article
Preoperative and Postoperative Serum Immunoglobulins

Author: Batool H. Al-Ghurabi*;Ph.D بتول الغرابي
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2007 Volume: 49 Issue: 2 Pages: 189-192
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Quantitation of serum immunoglobulins (IgG, IgA and IgM) provides useful information for the evaluation of certain cancers.Objectives:to estimate serum immunoglobulins level before and after surgery, and to shed light on the correlation of immunoglobulins with progression of CRC.Patients and Methodes. By single radial immune diffusion method IgG, IgA, IgM were estimated in 100 CRC patients preoperatively, and in 20 patients postoperatively compared with 35 patients control with ulcerative colitis (UC) and 50 healthy control.Results: The study showed significantly increased the serum IgM level in patients group preoperatively (p<0.001) compared with control group. On the other hand, no significant differences were observed in respect to the mean of IgG, IgA, and IgM after surgical excision of the tumor in 20 patients.Conclusion: These finding suggests that high level of IgM might be considered as prognostic indicator.Keywords: serum immunoglobulins, Colorectalcancer cases


Article
EFFECTS OF DEXAMETHASONE, ESTROGEN ADMINISTRATION ON LEPTIN, THYROID, REPRODUCTIVE HORMONE CONCENTRATION AND LIPID PROFILE OF FEMALE RABBITS SERUM.
تاثير اعطاء كل من الديكساميثازون وھرمون الاستروجين في تركيز كل من ھرمون اللبيتين وھرمونات الغدة الدرقية والتناسلية ومستوى دھون الدم في مصل دم اناث الارانب

Author: Rashad F.Ghadhban Ala AL-Deen H. Jawad رشاد فاضل غضبان علاء الدين حسن جواد
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2013 Volume: 12 Issue: 1 Pages: 41-53
Publisher: Basrah University جامعة البصرة

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Abstract

The aim of this study investigate the effects of long term administration ofDexamethasone (DEX.) 17 β-estradiol (EST.) on body weight, concentration of somehormones ( Leptin, thyroid and reproductive hormone) in addition to determination oflipid profile of female rabbits blood serum.Thirty local rabbits were subdivided randomly and equally into three groups. Thefirst group was used as a control which injected with normal saline . The second groupwas injected daily (0.5mg /kg B.W) DEX . Intramuscularly. The third group was injectedsubcutaneously daily with 0.3 mg /kg B.W s/c 17 β-estradiol. All groups in this studywere treated for 60 days , and blood collected every 15 days. Serum was tested for leptin,LH, FSH, T3, T4 hormones total Cholesterol(TC), HDL(height density lipo-protein),LDL (low density lipo- protein),TG (triglycerides), Body weight was taken every 15 daysfrom the first day .The result showed significant (P≤0.05) decreased in body weight afteradministration of both dexamethasone (DEX.) and Estrogen (EST.), significant increasedin leptin concentration with dexamethasone (DEX.) Treatment while significantdecreased with Estrogen (EST.) treatment, in the other hand LH and FSH concentrationshowed significant decreased in both treatment dexamethasone (DEX.) and Estrogen(EST.) thyroid hormone show significant decreased with dexamethasone (DEX.)Treatment and significant increased T3 & T4 hormone with Estrogen (EST.) treatment ascompare with control while the increase in the T4 it was occurred only in the periods (45and 60)days within treatment groups , lipid profile (TC,TG,LDL, HDL,VLDL) showsignificant increased with DEX. treatment while Significant decreased with EST.treatment


Article
SERUM LEPTIN LEVEL IN SEVERE PREECLAMPSIA

Authors: Maad M Shalal معد مهدي شلال --- Anwar N Al Bassam انوار نوري البصام --- Isra T Hassan اسراء طالب حسن
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2013 Volume: 11 Issue: 2 Pages: 144-147
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background:Preeclampsia is a major cause of maternal morbidity and mortality with unknown aetiology. Placental hypoperfusion and diffuse endothelial cell injury are considered the central pathological process. Many adipocyte hormones like leptin play an important role in the inflammatory and atherosclerotic process and may be used as a marker for preeclampsia.Objective:To find the role of serum leptin measurement in pregnant women as a marker of preeclampsia.Methods:Seventy six primigravida women in their 3rd trimester of pregnancy were studied; 44 of them with severe preeclampsia, while the other 32 women with normal blood pressure without any history of previous diseases. Blood samples were taken for serum leptin, uric acid and creatinine levels, urine samples were collected for albumin. Serum leptin level was measured by ELISA kits.Result:Serum leptin and uric acid levels but not the creatinine was different in eclamptic group than control group. Mean age, height and weight were not different between the two groups. The systolic and diastolic blood pressures were also different between the two groups. 26 cases (59.1%) had proteinuria of 3+ albumin and 18 cases (40.9%) with 4+.Conclusion:Elevated serum leptin level can be used as a marker in the assessment of preeclampsia.Key words:Primigravida, preeclampsia, serum lipten.


Article
STUDY OF SOME BIOCHEMICAL CHANGES IN URINE AND SERUM OF EXPERIMENTALLY- INDUCED UROLITHIASIS RABBITS BY SODIUM OXALATE

Author: Arwa , H.M.AL-Saeed اروى حميد السعيد
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2013 Volume: 12 Issue: 2 Pages: 47-54
Publisher: Basrah University جامعة البصرة

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Abstract

The present study was undertaken to find the alteration in some urine and serum parameters of urolithiasis rabbits induced by sodium oxalate .Animals were divided into two groups six in each, first group animals received only normal saline (0.9%) as control group , while second group animals were treated with sodium oxalate (70 mg / Kg b.w intraperitoneal ) daily for 15 days as treatment group . The results of urine analysis indicated that increased urine specific gravity , protein level and leukocytes , while decreased pH in treatment group as compared with control group , also observed that hemolysis in urine but there was no significant difference (p> 0.05) in urine level of glucose , Ketones , nitrite , urobilinogen and bilirubin in treatment group as compared with control group . The results of serum analysis indicated that there was no significant difference (p> 0.05) in serum level of calcium and phosphorus , while , increased serum level of sodium , potassium , uric acid and creatinine in treatment group as compared with control group . The study indicated that there was some changes in both urine and serum parameters in urolithasis .

Keywords

Serum --- Rabbits --- Sodium oxalate

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